Development Level

Tbio 25 | 11,445
Tdark 7 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
increased circulating alkaline... 2 | 122
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal retina morphology 1 | 71
decreased circulating alkaline... 1 | 46
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

Carcinoma 25 | 11,493
ovarian cancer 22 | 8,520
Bardet-Biedl syndrome 18 | 51
Ciliopathy 17 | 71
Polydactyly 17 | 107
Obesity 16 | 678
Bardet-Biedl syndrome 1 15 | 22
Intellectual disability 14 | 1,016
Retinitis Pigmentosa 13 | 226
ependymoma 13 | 4,679
medulloblastoma, large-cell 13 | 6,241
osteosarcoma 13 | 7,950
psoriasis 12 | 6,694
Cone dystrophy 10 | 71
Hypertensive disease 10 | 292
Increase in blood pressure 10 | 119
Short stature 10 | 531
Autosomal recessive predisposition 9 | 1,442
Nephronophthisis 9 | 80
Nystagmus 9 | 317
Retinal Degeneration 9 | 106
glioblastoma 9 | 5,792
Congenital hypoplasia of ovary 8 | 30
Congenital hypoplasia of penis 8 | 176
Dull intelligence 8 | 645
Electroretinogram abnormal 8 | 95
Fundus dystrophy 8 | 83
Hypogonadism 8 | 173
Hypoplastic ovary 8 | 30
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Multicystic Dysplastic Kidney 8 | 52
Poor school performance 8 | 645
Ulnar polydactyly of fingers 8 | 47
astrocytic glioma 8 | 2,597
atypical teratoid / rhabdoid tumor 8 | 5,112
oligodendroglioma 8 | 2,850
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Pick disease 7 | 1,894
Meckel syndrome 6 | 46
Small genitalia 6 | 13
chronic rhinosinusitis 6 | 512
malignant mesothelioma 6 | 3,232
tuberculosis 6 | 2,010
Breast cancer 5 | 3,578
Kidney cancer 5 | 2,613
Senior-Loken syndrome 5 | 22
adult high grade glioma 5 | 3,801
medulloblastoma 5 | 720
Asphyxiating thoracic dystrophy 4 | 44
Autosomal recessive polycystic kidney disease 4 | 41
Brachydactyly 4 | 156
Joubert syndrome 4 | 66
Renal dysplasia and retinal aplasia (disorder) 4 | 10
Strabismus 4 | 270
diabetes mellitus 4 | 1,728
gastric cancer 4 | 459
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
Abnormality of retinal pigmentation 3 | 111
Asthma 3 | 385
Astrocytoma, Pilocytic 3 | 3,081
Biliary Tract Diseases 3 | 16
Cancer 3 | 2,499
Choroidal sclerosis 3 | 8
Cystic kidney 3 | 30
Delayed speech and language development 3 | 112
High, narrow palate 3 | 32
Hirsutism 3 | 47
Hypodontia 3 | 81
Hypoplastic feet 3 | 66
Inadequate arch length for tooth size 3 | 45
Language Delay 3 | 112
Leber congenital amaurosis 3 | 69
Left Ventricular Hypertrophy 3 | 47
Nephrogenic Diabetes Insipidus 3 | 16
Polydactyly of toes 3 | 12
Radially deviated fingers 3 | 38
Reactive airway disease 3 | 21
Retinal pigment epithelial abnormality 3 | 111
Situs Inversus 3 | 65
Specific learning disability 3 | 47
Speech Delay 3 | 112
Speech Disorders 3 | 58
Speech impairment 3 | 112
Syndactyly 3 | 88
Tooth Crowding 3 | 45
Tooth mass arch size discrepancy 3 | 45
Tooth size discrepancy 3 | 45
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
posterior fossa group B ependymoma 3 | 416
primitive neuroectodermal tumor 3 | 3,035
progressive supranuclear palsy 3 | 676

Tissue

Blood and immune system 33 | 16,909
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678
Cardiovascular System 32 | 15,192
Respiratory system 31 | 16,393

Target Family

Non-IDG 27 | 12,091
Enzyme 4 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344

Compartment GO Term

BBSome 33 | 33
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Coiled-coil domain-containing protein 28B CCDC28B Tbio Non-IDG -0.62521 3.91 60
Protein CC2D2B CC2D2B Tdark Non-IDG 1.04 0.06 18
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -2.03755 107.9 152
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69
Rab-3A-interacting protein RAB3IP Tbio Non-IDG -1.03500 11.6 89
Ras-related protein Rab-8A RAB8A Tbio Enzyme -2.22872 157.9 190
BBSome-interacting protein 1 BBIP1 Tdark Non-IDG -0.24402 2.13 30
Somatostatin receptor type 3 SSTR3 Tclin GPCR -1.89900 68.6 106
Protein PTHB1 BBS9 Tbio Non-IDG -1.86939 69.5 115