Development Level

Tbio 48 | 11,445
Tchem 48 | 1,598
Tclin 14 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 5 | 499
embryonic lethality prior to t... 4 | 278
decreased circulating insulin ... 3 | 76
hyperactivity 3 | 148
increased mean corpuscular hem... 3 | 96
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
abnormal testis morphology 2 | 43
cataract 2 | 92
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 36
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
small superior vagus ganglion 2 | 74
small testis 2 | 58
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
absent testes 1 | 6
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
increased basophil cell number 1 | 7
increased bone mineral density 1 | 72
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
male infertility 1 | 123
mammalian phenotype 1 | 17
microphthalmia 1 | 26
short tibia 1 | 97
small seminal vesicle 1 | 10
thrombocytopenia 1 | 56
urinary bladder obstruction 1 | 4

Disease

Cancer 105 | 2,499
ovarian cancer 79 | 8,520
lung cancer 68 | 4,740
glioblastoma 67 | 5,792
Carcinoma 65 | 11,493
osteosarcoma 64 | 7,950
psoriasis 64 | 6,694
medulloblastoma, large-cell 49 | 6,241
malignant mesothelioma 48 | 3,232
atypical teratoid / rhabdoid tumor 47 | 5,112
diabetes mellitus 47 | 1,728
ependymoma 44 | 4,679
Vascular disease 43 | 319
Breast cancer 41 | 3,578
Prostatic Neoplasms 41 | 495
Breast Neoplasms 40 | 445
Mammary Neoplasms 40 | 425
Alzheimer's disease 38 | 658
Schizophrenia 35 | 1,160
adult high grade glioma 35 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 35 | 3,291
pancreatic cancer 35 | 2,398
Astrocytoma, Pilocytic 34 | 3,081
Obesity 34 | 678
Stomach Neoplasms 34 | 300
non-small cell lung cancer 34 | 2,890
ulcerative colitis 32 | 1,819
Lung Neoplasms 31 | 232
Toxic encephalopathy 31 | 141
lung adenocarcinoma 31 | 2,716
primitive neuroectodermal tumor 31 | 3,035
tuberculosis 31 | 2,010
Kidney disease 30 | 430
group 3 medulloblastoma 30 | 4,104
invasive ductal carcinoma 30 | 2,951
lung carcinoma 29 | 2,843
adrenocortical carcinoma 28 | 1,428
Arthritis 27 | 290
Heart disease 27 | 306
Carcinoma, Hepatocellular 25 | 228
Colonic Neoplasms 25 | 142
Liver Cirrhosis, Experimental 25 | 769
Liver carcinoma 25 | 240
breast carcinoma 25 | 1,638
Bipolar Disorder 24 | 666
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
oligodendroglioma 24 | 2,850
Asthma 23 | 385
Diabetes Mellitus, Experimental 23 | 108
Liver disease 23 | 237
Neoplasm Metastasis 23 | 168
acute quadriplegic myopathy 23 | 1,158
Brain Ischemia 22 | 110
Depressive disorder 22 | 409
Myocardial Infarction 22 | 151
Parkinson's disease 22 | 392
Rheumatoid arthritis 22 | 1,191
cystic fibrosis 22 | 1,696
interstitial cystitis 22 | 2,312
pituitary cancer 22 | 1,972
Adenoma 21 | 167
Eye disease 21 | 62
Multiple Sclerosis 21 | 540
Multiple myeloma 21 | 1,332
ductal carcinoma in situ 21 | 1,745
Adenocarcinoma 20 | 122
Anemia 20 | 365
Autosomal recessive predisposition 20 | 1,442
Endometriosis 20 | 540
Hyperglycemia 20 | 137
Hypertensive disease 20 | 292
Pancreatic Neoplasm 20 | 85
Reperfusion Injury 20 | 86
Squamous cell carcinoma 20 | 129
astrocytoma 20 | 1,146
colon cancer 20 | 1,478
hepatocellular carcinoma 20 | 547
subependymal giant cell astrocytoma 20 | 2,287
Hypertension 19 | 396
Lung disease 19 | 142
Melanoma 19 | 711
Pancreatic Neoplasms 19 | 85
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
Atherosclerosis 18 | 291
Brain disease 18 | 96
Kidney cancer 18 | 2,613
Mental Depression 18 | 333
juvenile dermatomyositis 18 | 1,187
Carcinoma, Squamous Cell 17 | 110
Cerebrovascular disease 17 | 238
Hypersensitivity reaction type II disease 17 | 253
Inflammation 17 | 120
Major Depressive Disorder 17 | 301
Neurodegenerative disease 17 | 414
cutaneous lupus erythematosus 17 | 1,057
Diabetes Mellitus, Non-Insulin-Dependent 16 | 145
nasopharyngeal carcinoma 16 | 1,058
pediatric high grade glioma 16 | 1,064
primary pancreatic ductal adenocarcinoma 16 | 1,109

Tissue

Blood and immune system 106 | 16,909
Digestive Tract 106 | 17,369
Endocrine System 106 | 18,159
Female tissues 105 | 17,400
Respiratory system 105 | 16,393
Skin and soft tissues 105 | 17,230
Liver and Pancreas 104 | 16,750
Male tissues 104 | 17,142
Nervous System 104 | 16,725
Urinary Tract 104 | 16,678
Cardiovascular System 102 | 15,192

Target Family

Non-IDG 55 | 12,091
Enzyme 26 | 4,145
Kinase 17 | 634
Transcription Factor 9 | 1,400
Epigenetic 2 | 242
Nuclear Receptor 2 | 48

Compartment GO Term

BAX complex 111 | 111
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Caspase-2 CASP2 Tchem Enzyme -2.62373 431.8 571
DNA mismatch repair protein Msh6 MSH6 Tbio Epigenetic -2.72594 572.3 479
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735
Eukaryotic translation initiation factor 2-alpha kinase 3 EIF2AK3 Tchem Kinase -3.05781 896.8 450
Bcl-2-related ovarian killer protein BOK Tbio Non-IDG -1.64193 42.6 207
Endonuclease G, mitochondrial ENDOG Tbio Enzyme -2.22791 175.9 334
Caspase-6 CASP6 Tchem Enzyme -2.49135 293.6 874