Development Level

Tchem 54 | 1,890
Tbio 35 | 10,625
Tclin 12 | 602

IMPC Term

preweaning lethality, complete... 5 | 633
embryonic lethality prior to t... 4 | 187
preweaning lethality, incomple... 3 | 260
abnormal embryo size 2 | 112
abnormal lens morphology 2 | 73
abnormal testis morphology 2 | 30
cataract 2 | 26
decreased circulating insulin ... 2 | 75
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased or absent threshold ... 2 | 128
small testis 2 | 37
abnormal QRS complex 1 | 25
abnormal bone mineralization 1 | 55
abnormal coat/hair pigmentatio... 1 | 54
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placement of pupils 1 | 4
abnormal retinal inner nuclear... 1 | 5
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal tooth morphology 1 | 24
decreased bone mineral content 1 | 157
decreased circulating creatini... 1 | 31
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
enlarged epididymis 1 | 27
enlarged spleen 1 | 26
female infertility 1 | 34
hydrops fetalis 1 | 22
increased bone mineral density 1 | 52
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
male infertility 1 | 62
microphthalmia 1 | 15
narrow eye opening 1 | 15
short tibia 1 | 82
small superior vagus ganglion 1 | 20
urinary bladder obstruction 1 | 2

Disease

Cancer 97 | 2,346
ovarian cancer 70 | 8,484
psoriasis 60 | 6,685
glioblastoma 59 | 5,572
lung cancer 58 | 4,466
osteosarcoma 57 | 7,933
diabetes mellitus 43 | 1,663
malignant mesothelioma 43 | 3,162
medulloblastoma, large-cell 43 | 6,234
Mammary Neoplasms 37 | 410
Vascular disease 37 | 281
Prostatic Neoplasms 36 | 471
atypical teratoid / rhabdoid tumor 34 | 4,369
pediatric high grade glioma 34 | 2,712
pilocytic astrocytoma 34 | 3,086
ulcerative colitis 34 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,289
pancreatic cancer 33 | 2,300
Alzheimer's disease 32 | 644
Breast cancer 32 | 3,094
Kidney disease 30 | 396
Lung Neoplasms 30 | 171
lung adenocarcinoma 30 | 2,713
non-small cell lung cancer 30 | 2,798
Obesity 28 | 616
Stomach Neoplasms 28 | 282
lung carcinoma 28 | 2,844
primitive neuroectodermal tumor 28 | 3,031
Toxic encephalopathy 27 | 131
adrenocortical carcinoma 27 | 1,427
invasive ductal carcinoma 26 | 2,950
Arthritis 25 | 248
Heart disease 24 | 279
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
tuberculosis 24 | 1,557
Diabetes Mellitus, Experimental 23 | 106
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
Colonic Neoplasms 22 | 126
Liver carcinoma 22 | 217
interstitial cystitis 22 | 2,299
oligodendroglioma 22 | 2,849
posterior fossa group A ependymoma 22 | 1,511
Adenoma 21 | 165
Asthma 21 | 349
Brain Ischemia 21 | 87
Liver disease 21 | 219
Neoplasm Metastasis 21 | 138
Rheumatoid Arthritis 21 | 1,160
acute quadriplegic myopathy 21 | 1,157
cystic fibrosis 21 | 1,665
pituitary cancer 21 | 1,972
Myocardial Infarction 20 | 126
Reperfusion Injury 20 | 84
astrocytoma 20 | 1,493
colon cancer 20 | 1,475
Atherosclerosis 19 | 275
Lung disease 19 | 132
Multiple Sclerosis 19 | 498
Multiple myeloma 19 | 1,327
Pancreatic Neoplasm 19 | 79
Parkinson's disease 19 | 364
ductal carcinoma in situ 19 | 1,745
subependymal giant cell astrocytoma 19 | 2,287
Endometriosis 18 | 535
Eye disease 18 | 55
Adenocarcinoma 17 | 115
Diabetes Mellitus, Non-Insulin-Dependent 17 | 157
Hyperglycemia 17 | 120
cutaneous lupus erythematosus 17 | 1,056
juvenile dermatomyositis 17 | 1,189
primary pancreatic ductal adenocarcinoma 17 | 1,271
Hypersensitivity reaction type II disease 16 | 235
Inflammation 16 | 109
Melanoma 16 | 261
Peripheral Neuropathy 16 | 303
breast carcinoma 16 | 1,614
ependymoma 16 | 2,514
group 4 medulloblastoma 16 | 1,875
Cardiomyopathies 15 | 90
Cerebrovascular disease 15 | 231
Esophageal Neoplasms 15 | 67
Inflammatory bowel disease 15 | 142
Neoplasm Invasiveness 15 | 127
nasopharyngeal carcinoma 15 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,795
Brain disease 14 | 83
Chronic Lymphocytic Leukemia 14 | 242
Colorectal Neoplasms 14 | 217
Drug-Induced Liver Injury 14 | 118
Hypertensive disease 14 | 193
Mammary Neoplasms, Experimental 14 | 150
Myocardial Reperfusion Injury 14 | 34
Neurodegenerative disease 14 | 383
group 3 medulloblastoma 14 | 2,254
non-small cell lung carcinoma 14 | 413
ovarian neoplasm 14 | 97
acute myeloid leukemia 13 | 780
aldosterone-producing adenoma 13 | 664
astrocytic glioma 13 | 2,241
sonic hedgehog group medulloblastoma 13 | 1,482

Tissue

Blood and immune system 100 | 17,995
Digestive Tract 100 | 18,473
Endocrine System 100 | 18,512
Female tissues 100 | 18,647
Liver and Pancreas 100 | 18,136
Male tissues 100 | 17,969
Nervous System 100 | 18,561
Respiratory system 100 | 17,484
Urinary Tract 100 | 18,444
Skin and soft tissues 99 | 18,115
Cardiovascular System 98 | 17,958

Target Family

Non-IDG 51 | 11,971
Enzyme 26 | 4,146
Kinase 14 | 634
Transcription Factor 6 | 1,400
Epigenetic 2 | 242
Nuclear Receptor 2 | 48

Compartment GO Term

BAX complex 101 | 101
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.27492 2052.7 1794
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.90528 8199.7 1129
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648
G1/S-specific cyclin-D1 CCND1 Tchem Non-IDG -3.77851 5447.1 1111
78 kDa glucose-regulated protein HSPA5 Tchem Non-IDG -3.28487 2003.3 918
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43357 2997.4 1177