Development Level

Tbio 31 | 11,651
Tchem 9 | 1,388

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal embryo size 2 | 220
edema 2 | 59
prenatal lethality prior to he... 2 | 87
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
abnormal urinary bladder morph... 1 | 11
decreased NK T cell number 1 | 2
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased grip strength 1 | 116
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
increased blood uric acid leve... 1 | 5
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

osteosarcoma 28 | 7,950
ovarian cancer 28 | 8,520
Carcinoma 27 | 11,493
Cancer 19 | 2,499
group 3 medulloblastoma 19 | 4,104
medulloblastoma, large-cell 16 | 6,241
psoriasis 16 | 6,694
ependymoma 15 | 4,679
lung cancer 15 | 4,740
Breast cancer 14 | 3,578
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 14 | 5,792
Intellectual disability 13 | 1,016
Kidney cancer 12 | 2,613
lung adenocarcinoma 12 | 2,716
primitive neuroectodermal tumor 12 | 3,035
Coffin-Siris syndrome 10 | 17
malignant mesothelioma 10 | 3,232
Rheumatoid arthritis 9 | 1,191
Short stature 9 | 531
astrocytic glioma 9 | 2,597
oligodendroglioma 9 | 2,850
Broad flat nasal bridge 8 | 236
Dull intelligence 8 | 645
Epilepsy 8 | 792
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Muscle hypotonia 8 | 571
Nasal bridge wide 8 | 236
Poor school performance 8 | 645
Seizures 8 | 596
Small head 8 | 374
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
Cognitive delay 7 | 608
Cryptorchidism 7 | 296
Fetal Growth Retardation 7 | 189
Global developmental delay 7 | 608
Infant, Small for Gestational Age 7 | 176
Intrauterine retardation 7 | 176
Mental and motor retardation 7 | 608
Waldenstrons macroglobulinemia 7 | 765
acute myeloid leukemia 7 | 783
adult high grade glioma 7 | 3,801
spina bifida 7 | 1,074
Acquired scoliosis 6 | 281
Astrocytoma, Pilocytic 6 | 3,081
Concave bridge of nose 6 | 195
Curvature of spine 6 | 282
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Full lower lip 6 | 64
Macrostomia 6 | 72
Pick disease 6 | 1,894
Prominent lower lip 6 | 64
Strabismus 6 | 270
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
pediatric high grade glioma 6 | 1,064
progressive supranuclear palsy 6 | 676
Abnormality of cardiovascular system morphology 5 | 23
Adenoid Cystic Carcinoma 5 | 99
Bushy eyebrows 5 | 49
Carcinoma, Adenoid Cystic 5 | 99
Coarse facial features 5 | 108
Congenital deafness 5 | 185
Deafness 5 | 198
Depressed nasal ridge 5 | 51
Feeding difficulties in infancy 5 | 175
Hearing Loss, Partial 5 | 185
Liver cancer 5 | 604
Long eyelashes 5 | 37
Multiple myeloma 5 | 1,332
Schizophrenia 5 | 1,160
Thickened facial skin with coarse facial features 5 | 108
aldosterone-producing adenoma 5 | 665
dermatomyositis 5 | 966
group 4 medulloblastoma 5 | 1,855
hearing impairment 5 | 199
pancreatic cancer 5 | 2,398
Blepharoptosis 4 | 231
Carcinoma, Hepatocellular 4 | 228
Cerebellar hypoplasia and atrophy 4 | 41
Generalized hirsutism 4 | 36
Hypoplastic mandible condyle 4 | 275
Immune system cancer 4 | 140
Joint hyperflexibility 4 | 78
Large intestine cancer 4 | 126
Liver carcinoma 4 | 240
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Nystagmus 4 | 317
Recurrent respiratory infections 4 | 141
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
non-small cell lung cancer 4 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Skin and soft tissues 40 | 17,230
Endocrine System 39 | 18,159
Blood and immune system 38 | 16,909
Cardiovascular System 38 | 15,192
Digestive Tract 38 | 17,369
Female tissues 38 | 17,400
Liver and Pancreas 38 | 16,750
Male tissues 38 | 17,142
Nervous System 38 | 16,725
Respiratory system 37 | 16,393
Urinary Tract 36 | 16,678

Target Family

Non-IDG 19 | 12,091
Epigenetic 11 | 242
Transcription Factor 5 | 1,400
TF/Epigenetic 3 | 38
Enzyme 1 | 4,145
Kinase 1 | 634

Compartment GO Term

BAF-type complex 40 | 40
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein-tyrosine kinase 6 PTK6 Tchem Kinase -2.20657 183.7 368
Akirin-2 AKIRIN2 Tbio Non-IDG -1.25613 22.0 152
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 SMARCB1 Tbio Non-IDG -2.77635 619.8 379
Probable global transcription activator SNF2L2 SMARCA2 Tchem Epigenetic -2.57435 345.3 153
Transcription activator BRG1 SMARCA4 Tchem Epigenetic -2.86389 713.1 332
Histone acetyltransferase p300 EP300 Tchem Epigenetic -3.79743 6016.7 775
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 SMARCE1 Tbio Transcription Factor -1.51153 35.7 270
Actin-like protein 6A ACTL6A Tbio Non-IDG -1.45479 28.3 286
SWI/SNF complex subunit SMARCC2 SMARCC2 Tbio TF/Epigenetic -1.27787 15.2 140
Histone acetyltransferase KAT2B KAT2B Tchem Epigenetic -2.62847 372.0 331