Development Level

Tbio 31 | 11,445
Tchem 9 | 1,598

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal embryo size 2 | 220
edema 2 | 59
prenatal lethality prior to he... 2 | 87
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
abnormal urinary bladder morph... 1 | 11
decreased NK T cell number 1 | 2
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased grip strength 1 | 116
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
increased blood uric acid leve... 1 | 5
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

osteosarcoma 28 | 7,950
ovarian cancer 28 | 8,520
Carcinoma 27 | 11,493
Cancer 19 | 2,499
group 3 medulloblastoma 19 | 4,104
medulloblastoma, large-cell 16 | 6,241
psoriasis 16 | 6,694
ependymoma 15 | 4,679
lung cancer 15 | 4,740
Breast cancer 14 | 3,578
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 14 | 5,792
Intellectual disability 13 | 1,016
Kidney cancer 12 | 2,613
lung adenocarcinoma 12 | 2,716
primitive neuroectodermal tumor 12 | 3,035
Coffin-Siris syndrome 10 | 17
malignant mesothelioma 10 | 3,232
Rheumatoid arthritis 9 | 1,191
Short stature 9 | 531
astrocytic glioma 9 | 2,597
oligodendroglioma 9 | 2,850
Broad flat nasal bridge 8 | 236
Dull intelligence 8 | 645
Epilepsy 8 | 792
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Muscle hypotonia 8 | 571
Nasal bridge wide 8 | 236
Poor school performance 8 | 645
Seizures 8 | 596
Small head 8 | 374
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
Cognitive delay 7 | 608
Cryptorchidism 7 | 296
Fetal Growth Retardation 7 | 189
Global developmental delay 7 | 608
Infant, Small for Gestational Age 7 | 176
Intrauterine retardation 7 | 176
Mental and motor retardation 7 | 608
Waldenstrons macroglobulinemia 7 | 765
acute myeloid leukemia 7 | 783
adult high grade glioma 7 | 3,801
spina bifida 7 | 1,074
Acquired scoliosis 6 | 281
Astrocytoma, Pilocytic 6 | 3,081
Concave bridge of nose 6 | 195
Curvature of spine 6 | 282
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Full lower lip 6 | 64
Macrostomia 6 | 72
Pick disease 6 | 1,894
Prominent lower lip 6 | 64
Strabismus 6 | 270
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
pediatric high grade glioma 6 | 1,064
progressive supranuclear palsy 6 | 676
Abnormality of cardiovascular system morphology 5 | 23
Adenoid Cystic Carcinoma 5 | 99
Bushy eyebrows 5 | 49
Carcinoma, Adenoid Cystic 5 | 99
Coarse facial features 5 | 108
Congenital deafness 5 | 185
Deafness 5 | 198
Depressed nasal ridge 5 | 51
Feeding difficulties in infancy 5 | 175
Hearing Loss, Partial 5 | 185
Liver cancer 5 | 604
Long eyelashes 5 | 37
Multiple myeloma 5 | 1,332
Schizophrenia 5 | 1,160
Thickened facial skin with coarse facial features 5 | 108
aldosterone-producing adenoma 5 | 665
dermatomyositis 5 | 966
group 4 medulloblastoma 5 | 1,855
hearing impairment 5 | 199
pancreatic cancer 5 | 2,398
Blepharoptosis 4 | 231
Carcinoma, Hepatocellular 4 | 228
Cerebellar hypoplasia and atrophy 4 | 41
Generalized hirsutism 4 | 36
Hypoplastic mandible condyle 4 | 275
Immune system cancer 4 | 140
Joint hyperflexibility 4 | 78
Large intestine cancer 4 | 126
Liver carcinoma 4 | 240
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Nystagmus 4 | 317
Recurrent respiratory infections 4 | 141
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
non-small cell lung cancer 4 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Skin and soft tissues 40 | 17,230
Endocrine System 39 | 18,159
Blood and immune system 38 | 16,909
Cardiovascular System 38 | 15,192
Digestive Tract 38 | 17,369
Female tissues 38 | 17,400
Liver and Pancreas 38 | 16,750
Male tissues 38 | 17,142
Nervous System 38 | 16,725
Respiratory system 37 | 16,393
Urinary Tract 36 | 16,678

Target Family

Non-IDG 19 | 12,091
Epigenetic 11 | 242
Transcription Factor 5 | 1,400
TF/Epigenetic 3 | 38
Enzyme 1 | 4,145
Kinase 1 | 634

Compartment GO Term

BAF-type complex 40 | 40
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.20560 145.6 116
PHD finger protein 10 PHF10 Tbio Epigenetic -1.09430 12.5 53
Protein polybromo-1 PBRM1 Tchem TF/Epigenetic -1.92500 84.6 97
Natural cytotoxicity triggering receptor 1 NCR1 Tbio Non-IDG -2.43156 271.6 456
Actin-like protein 6B ACTL6B Tbio Non-IDG -0.88819 7.82 127
Calcium-responsive transactivator SS18L1 Tbio Non-IDG -0.77788 6.30 92
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 SMARCAL1 Tbio Non-IDG -1.74852 65.1 133
AT-rich interactive domain-containing protein 1B ARID1B Tbio Transcription Factor -1.88304 66.9 120
Retinoblastoma-associated protein RB1 Tchem Non-IDG -3.07052 1137.4 2150
Zinc finger protein neuro-d4 DPF1 Tbio Epigenetic -0.99036 9.89 130