Development Level

Tbio 53 | 11,445
Tclin 22 | 613
Tchem 21 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased hemoglobin content 3 | 68
decreased leukocyte cell numbe... 3 | 73
preweaning lethality, incomple... 3 | 499
decreased body weight 2 | 161
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased monocyte cell number 2 | 63
increased total body fat amoun... 2 | 134
male infertility 2 | 123
small superior vagus ganglion 2 | 74
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal maxilla morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
corneal opacity 1 | 32
decreased IgG3 level 1 | 1
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged spleen 1 | 41
female infertility 1 | 60
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased CD4-positive, alpha ... 1 | 4
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased heart left ventricle... 1 | 4
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
prenatal lethality prior to he... 1 | 87
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Cancer 81 | 2,499
Carcinoma 67 | 11,493
osteosarcoma 64 | 7,950
ovarian cancer 51 | 8,520
psoriasis 49 | 6,694
lung cancer 40 | 4,740
glioblastoma 37 | 5,792
medulloblastoma, large-cell 35 | 6,241
malignant mesothelioma 31 | 3,232
Kidney cancer 30 | 2,613
tuberculosis 30 | 2,010
ulcerative colitis 30 | 1,819
Anemia 29 | 365
interstitial cystitis 29 | 2,312
invasive ductal carcinoma 29 | 2,951
Rheumatoid arthritis 27 | 1,191
Breast cancer 26 | 3,578
Thrombocytopenia 26 | 197
lung carcinoma 26 | 2,843
adult high grade glioma 24 | 3,801
subependymal giant cell astrocytoma 24 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
primary Sjogren syndrome 22 | 735
Astrocytoma, Pilocytic 21 | 3,081
Multiple myeloma 21 | 1,332
non-small cell lung cancer 21 | 2,890
atypical teratoid / rhabdoid tumor 20 | 5,112
cutaneous lupus erythematosus 19 | 1,057
ependymoma 19 | 4,679
pancreatic cancer 19 | 2,398
Multiple Sclerosis 18 | 540
Splenomegaly 18 | 190
group 3 medulloblastoma 18 | 4,104
group 4 medulloblastoma 18 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
lung adenocarcinoma 18 | 2,716
Arthritis 17 | 290
Diarrhea 17 | 253
Hypersensitivity reaction type II disease 17 | 253
Immune system cancer 17 | 140
cystic fibrosis 17 | 1,696
diabetes mellitus 17 | 1,728
Breast Neoplasms 16 | 445
Hypereosinophilic syndrome 16 | 71
Lymphoid leukemia 16 | 160
Mammary Neoplasms 16 | 425
breast carcinoma 16 | 1,638
ductal carcinoma in situ 16 | 1,745
Allergic hypersensitivity disease 15 | 126
Fatigue 15 | 182
Kidney disease 15 | 430
Lymphoproliferative syndrome 15 | 58
astrocytic glioma 15 | 2,597
Hepatomegaly 14 | 285
Lymphoma 14 | 81
Mastocytosis 14 | 27
Vascular disease 14 | 319
primitive neuroectodermal tumor 14 | 3,035
Acquired immunodeficiency syndrome 13 | 197
Asthma 13 | 385
Autosomal recessive predisposition 13 | 1,442
Fever 13 | 138
Leukemia 13 | 104
Liver Cirrhosis, Experimental 13 | 769
Melanoma 13 | 711
Polycythemia vera 13 | 27
Systemic lupus erythematosus 13 | 194
colon cancer 13 | 1,478
oligodendroglioma 13 | 2,850
Inflammatory bowel disease 12 | 151
Pneumonia 12 | 174
nasopharyngeal carcinoma 12 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
pituitary cancer 12 | 1,972
Influenza 11 | 142
Leukemia, Myelocytic, Acute 11 | 120
Neutropenia 11 | 72
Precursor Cell Lymphoblastic Leukemia-Lymphoma 11 | 49
Schizophrenia 11 | 1,160
Somatic mutation 11 | 61
Thrombocytosis 11 | 38
periodontitis 11 | 293
Agammaglobulinemia 10 | 34
Chronic Lymphocytic Leukemia 10 | 262
Failure to gain weight 10 | 365
Immunologic Deficiency Syndromes 10 | 113
Leukemia, Myeloid, Acute 10 | 105
Lung Neoplasms 10 | 232
Macroglobulinemia 10 | 18
Malaria 10 | 160
Pediatric failure to thrive 10 | 365
Pick disease 10 | 1,894
Precursor Cell Lymphoblastic Leukemia Lymphoma 10 | 43
Renal Cell Carcinoma 10 | 214
Severe combined immunodeficiency 10 | 51
Skin cancer 10 | 469
Waldenstrons macroglobulinemia 10 | 765
astrocytoma 10 | 1,146
primary pancreatic ductal adenocarcinoma 10 | 1,109

Tissue

Blood and immune system 94 | 16,909
Endocrine System 93 | 18,159
Male tissues 93 | 17,142
Digestive Tract 92 | 17,369
Skin and soft tissues 92 | 17,230
Urinary Tract 92 | 16,678
Female tissues 91 | 17,400
Liver and Pancreas 91 | 16,750
Respiratory system 91 | 16,393
Nervous System 87 | 16,725
Cardiovascular System 85 | 15,192

Target Family

Non-IDG 53 | 12,091
Enzyme 16 | 4,145
Kinase 15 | 634
Transcription Factor 13 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

Compartment GO Term

B cell receptor complex 100 | 100
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
B-cell antigen receptor complex-associated protein alpha chain CD79A Tbio Non-IDG -4.45149 28259.4 1170
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.36734 20160.1 3565
Prostate-specific antigen KLK3 Tchem Enzyme -4.31480 19470.8 1687
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.11278 12358.0 2705
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -4.00292 9201.7 1455
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325