Development Level

Tbio 53 | 11,445
Tclin 22 | 613
Tchem 21 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased hemoglobin content 3 | 68
decreased leukocyte cell numbe... 3 | 73
preweaning lethality, incomple... 3 | 499
decreased body weight 2 | 161
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased monocyte cell number 2 | 63
increased total body fat amoun... 2 | 134
male infertility 2 | 123
small superior vagus ganglion 2 | 74
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal maxilla morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
corneal opacity 1 | 32
decreased IgG3 level 1 | 1
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged spleen 1 | 41
female infertility 1 | 60
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased CD4-positive, alpha ... 1 | 4
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased heart left ventricle... 1 | 4
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
prenatal lethality prior to he... 1 | 87
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Cancer 81 | 2,499
Carcinoma 67 | 11,493
osteosarcoma 64 | 7,950
ovarian cancer 51 | 8,520
psoriasis 49 | 6,694
lung cancer 40 | 4,740
glioblastoma 37 | 5,792
medulloblastoma, large-cell 35 | 6,241
malignant mesothelioma 31 | 3,232
Kidney cancer 30 | 2,613
tuberculosis 30 | 2,010
ulcerative colitis 30 | 1,819
Anemia 29 | 365
interstitial cystitis 29 | 2,312
invasive ductal carcinoma 29 | 2,951
Rheumatoid arthritis 27 | 1,191
Breast cancer 26 | 3,578
Thrombocytopenia 26 | 197
lung carcinoma 26 | 2,843
adult high grade glioma 24 | 3,801
subependymal giant cell astrocytoma 24 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
primary Sjogren syndrome 22 | 735
Astrocytoma, Pilocytic 21 | 3,081
Multiple myeloma 21 | 1,332
non-small cell lung cancer 21 | 2,890
atypical teratoid / rhabdoid tumor 20 | 5,112
cutaneous lupus erythematosus 19 | 1,057
ependymoma 19 | 4,679
pancreatic cancer 19 | 2,398
Multiple Sclerosis 18 | 540
Splenomegaly 18 | 190
group 3 medulloblastoma 18 | 4,104
group 4 medulloblastoma 18 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
lung adenocarcinoma 18 | 2,716
Arthritis 17 | 290
Diarrhea 17 | 253
Hypersensitivity reaction type II disease 17 | 253
Immune system cancer 17 | 140
cystic fibrosis 17 | 1,696
diabetes mellitus 17 | 1,728
Breast Neoplasms 16 | 445
Hypereosinophilic syndrome 16 | 71
Lymphoid leukemia 16 | 160
Mammary Neoplasms 16 | 425
breast carcinoma 16 | 1,638
ductal carcinoma in situ 16 | 1,745
Allergic hypersensitivity disease 15 | 126
Fatigue 15 | 182
Kidney disease 15 | 430
Lymphoproliferative syndrome 15 | 58
astrocytic glioma 15 | 2,597
Hepatomegaly 14 | 285
Lymphoma 14 | 81
Mastocytosis 14 | 27
Vascular disease 14 | 319
primitive neuroectodermal tumor 14 | 3,035
Acquired immunodeficiency syndrome 13 | 197
Asthma 13 | 385
Autosomal recessive predisposition 13 | 1,442
Fever 13 | 138
Leukemia 13 | 104
Liver Cirrhosis, Experimental 13 | 769
Melanoma 13 | 711
Polycythemia vera 13 | 27
Systemic lupus erythematosus 13 | 194
colon cancer 13 | 1,478
oligodendroglioma 13 | 2,850
Inflammatory bowel disease 12 | 151
Pneumonia 12 | 174
nasopharyngeal carcinoma 12 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
pituitary cancer 12 | 1,972
Influenza 11 | 142
Leukemia, Myelocytic, Acute 11 | 120
Neutropenia 11 | 72
Precursor Cell Lymphoblastic Leukemia-Lymphoma 11 | 49
Schizophrenia 11 | 1,160
Somatic mutation 11 | 61
Thrombocytosis 11 | 38
periodontitis 11 | 293
Agammaglobulinemia 10 | 34
Chronic Lymphocytic Leukemia 10 | 262
Failure to gain weight 10 | 365
Immunologic Deficiency Syndromes 10 | 113
Leukemia, Myeloid, Acute 10 | 105
Lung Neoplasms 10 | 232
Macroglobulinemia 10 | 18
Malaria 10 | 160
Pediatric failure to thrive 10 | 365
Pick disease 10 | 1,894
Precursor Cell Lymphoblastic Leukemia Lymphoma 10 | 43
Renal Cell Carcinoma 10 | 214
Severe combined immunodeficiency 10 | 51
Skin cancer 10 | 469
Waldenstrons macroglobulinemia 10 | 765
astrocytoma 10 | 1,146
primary pancreatic ductal adenocarcinoma 10 | 1,109

Tissue

Blood and immune system 94 | 16,909
Endocrine System 93 | 18,159
Male tissues 93 | 17,142
Digestive Tract 92 | 17,369
Skin and soft tissues 92 | 17,230
Urinary Tract 92 | 16,678
Female tissues 91 | 17,400
Liver and Pancreas 91 | 16,750
Respiratory system 91 | 16,393
Nervous System 87 | 16,725
Cardiovascular System 85 | 15,192

Target Family

Non-IDG 53 | 12,091
Enzyme 16 | 4,145
Kinase 15 | 634
Transcription Factor 13 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

Compartment GO Term

B cell receptor complex 100 | 100
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 13C TNFRSF13C Tbio Non-IDG -2.48953 288.2 437
Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C Tbio Non-IDG -2.61667 619.4 0
Cytokine receptor-like factor 2 CRLF2 Tbio Non-IDG -1.91113 78.7 393
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
Interferon alpha-1/13 IFNA13 Tbio Non-IDG -3.87160 7663.4 500
AF4/FMR2 family member 1 AFF1 Tbio Transcription Factor -2.60388 403.1 201
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
Immunoglobulin lambda constant 1 IGLC1 Tbio Non-IDG -1.96217 230.7 0