Development Level

Tbio 45 | 11,178
Tdark 22 | 6,569

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
preweaning lethality, complete... 3 | 979
decreased total body fat amoun... 2 | 207
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal ileum morphology 1 | 2
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
edema 1 | 59
embryonic lethality prior to o... 1 | 239
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased lean body mass 1 | 172
polycystic kidney 1 | 15

Disease

Carcinoma 49 | 11,192
Primary ciliary dyskinesia 41 | 75
ependymoma 40 | 4,559
nasopharyngeal carcinoma 30 | 1,024
Kartagener Syndrome 28 | 38
Ciliary Motility Disorders 27 | 38
Situs Inversus 25 | 61
osteosarcoma 23 | 7,766
Ciliary Dyskinesia, Primary, 1 21 | 27
chronic rhinosinusitis 21 | 505
medulloblastoma, large-cell 21 | 6,086
Kidney cancer 18 | 2,548
ovarian cancer 18 | 8,297
psoriasis 18 | 6,514
glioblastoma 16 | 5,635
Breast cancer 14 | 3,469
lung adenocarcinoma 14 | 2,627
Male infertility 13 | 199
atypical teratoid / rhabdoid tumor 13 | 4,971
Autosomal recessive predisposition 12 | 1,407
Liver cancer 12 | 589
adult high grade glioma 12 | 3,701
Recurrent respiratory infections 11 | 138
group 3 medulloblastoma 11 | 4,002
lung carcinoma 11 | 2,755
Bronchiectasis 10 | 63
Melanoma 10 | 689
Sinusitis 9 | 63
lung cancer 9 | 4,607
pituitary cancer 8 | 1,915
Astrocytoma, Pilocytic 7 | 3,006
Endometrial cancer 7 | 301
Situs ambiguus 7 | 22
Skin cancer 7 | 451
group 4 medulloblastoma 7 | 1,806
DOID:2627 6 | 89
interstitial cystitis 6 | 2,237
malignant mesothelioma 6 | 3,135
non-small cell lung cancer 6 | 2,799
Dextrocardia 5 | 10
Paranasal Sinus Diseases 5 | 34
Recurrent sinus disease 5 | 22
Recurrent sinusitis 5 | 22
Right atrial isomerism 5 | 27
astrocytic glioma 5 | 2,530
cutaneous lupus erythematosus 5 | 1,016
cystic fibrosis and chronic rhinosinusitis 5 | 211
fibroadenoma 5 | 538
pancreatic cancer 5 | 2,322
primitive neuroectodermal tumor 5 | 2,957
tuberculosis 5 | 1,963
Hydrocephalus 4 | 148
Pick disease 4 | 1,856
Recurrent otitis media 4 | 41
Rigid spine muscular dystrophy 1 4 | 14
active ulcerative colitis 4 | 736
colon cancer 4 | 1,428
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,872
medulloblastoma 4 | 702
Abnormal respiratory motile cilium morphology 3 | 3
Alzheimer's disease 3 | 640
Bronchitis, Chronic 3 | 12
Infertility 3 | 176
Large intestine cancer 3 | 123
Nasal Polyps 3 | 10
Nasal inflammation 3 | 7
Polydactyly 3 | 106
Respiratory insufficiency due to defective ciliary clearance 3 | 6
Rhinitis 3 | 54
active Crohn's disease 3 | 882
adrenocortical carcinoma 3 | 1,385
breast carcinoma 3 | 1,589
ductal carcinoma in situ 3 | 1,686
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,204
posterior fossa group B ependymoma 3 | 406
Asthma 2 | 370
Bipolar Disorder 2 | 646
Cancer 2 | 2,388
Cardiovascular system disease 2 | 240
Chronic otitis media 2 | 52
Endometriosis 2 | 521
Immune system cancer 2 | 136
Microcephaly 2 | 166
Multiple myeloma 2 | 1,296
Omphalocele 2 | 24
Osteoporosis 2 | 348
Parkinson's disease 2 | 378
Vascular disease 2 | 294
Visceral heterotaxy 2 | 12
acute myeloid leukemia 2 | 760
atypical teratoid/rhabdoid tumor 2 | 349
cystic fibrosis 2 | 1,629
ear infection chronic 2 | 52
facioscapulohumeral dystrophy 2 | 281
gastric cancer 2 | 445
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,902
invasive ductal carcinoma 2 | 2,867
non-small cell lung carcinoma 2 | 302
oligodendroglioma 2 | 2,768
pediatric high grade glioma 2 | 1,035

Tissue

Endocrine System 67 | 18,159
Skin and soft tissues 65 | 17,230
Respiratory system 64 | 16,393
Female tissues 63 | 17,400
Male tissues 62 | 17,142
Digestive Tract 60 | 17,369
Urinary Tract 59 | 16,678
Nervous System 58 | 16,725
Blood and immune system 57 | 16,909
Liver and Pancreas 57 | 16,750
Cardiovascular System 44 | 15,192

Target Family

Non-IDG 62 | 12,091
Enzyme 3 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634

Compartment GO Term

Axoneme part 67 | 67
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dynein assembly factor with WDR repeat domains 1 DAW1 Tdark Non-IDG -0.80163 6.92 13
Dynein heavy chain 5, axonemal DNAH5 Tbio Non-IDG -1.46000 27.2 32
Dynein heavy chain 2, axonemal DNAH2 Tdark Non-IDG -0.65482 4.13 58
Dynein light chain roadblock-type 2 DYNLRB2 Tbio Non-IDG -0.65444 2.59 77
Dynein heavy chain 1, axonemal DNAH1 Tbio Non-IDG -1.30285 17.4 21
Nucleoside diphosphate kinase homolog 5 NME5 Tbio Kinase -0.86091 6.37 122
Thioredoxin domain-containing protein 3 NME8 Tbio Non-IDG -1.03981 11.2 79
Dynein light chain roadblock-type 1 DYNLRB1 Tbio Non-IDG -2.23639 168.6 41
Dynein heavy chain 3, axonemal DNAH3 Tdark Non-IDG -1.15833 13.8 12
Sperm-associated antigen 16 protein SPAG16 Tbio Non-IDG -1.42366 26.3 130