Development Level

Tbio 95 | 11,651
Tdark 41 | 6,593
Tclin 4 | 612
Tchem 2 | 1,388

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 8 | 499
abnormal behavior 3 | 298
edema 3 | 59
embryonic lethality prior to t... 3 | 278
male infertility 3 | 123
abnormal embryo size 2 | 220
decreased body length 2 | 101
decreased body weight 2 | 161
decreased fasted circulating g... 2 | 65
hyperactivity 2 | 148
increased fasted circulating g... 2 | 76
abnormal coat appearance 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal ileum morphology 1 | 2
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal response to tactile s... 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
anophthalmia 1 | 33
decreased B cell number 1 | 5
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hypoactivity 1 | 132
increased body weight 1 | 25
increased circulating chloride... 1 | 41
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
long tibia 1 | 25
microphthalmia 1 | 26
polycystic kidney 1 | 15
polydactyly 1 | 7
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97

Disease

Carcinoma 100 | 11,493
ependymoma 80 | 4,679
osteosarcoma 56 | 7,950
ovarian cancer 53 | 8,520
Primary ciliary dyskinesia 47 | 76
chronic rhinosinusitis 41 | 512
nasopharyngeal carcinoma 41 | 1,058
psoriasis 39 | 6,694
Kidney cancer 38 | 2,613
medulloblastoma, large-cell 37 | 6,241
atypical teratoid / rhabdoid tumor 35 | 5,112
glioblastoma 34 | 5,792
Ciliary Motility Disorders 30 | 38
Kartagener Syndrome 29 | 38
Situs Inversus 29 | 65
Breast cancer 28 | 3,578
lung adenocarcinoma 27 | 2,716
adult high grade glioma 24 | 3,801
Autosomal recessive predisposition 22 | 1,442
group 3 medulloblastoma 22 | 4,104
lung cancer 22 | 4,740
Ciliary Dyskinesia, Primary, 1 21 | 27
Liver cancer 19 | 604
astrocytic glioma 19 | 2,597
lung carcinoma 18 | 2,843
primitive neuroectodermal tumor 18 | 3,035
Astrocytoma, Pilocytic 17 | 3,081
Male infertility 17 | 206
Pick disease 16 | 1,894
Polydactyly 16 | 107
Nephronophthisis 15 | 80
malignant mesothelioma 15 | 3,232
Ciliopathy 14 | 71
Intellectual disability 14 | 1,016
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
non-small cell lung cancer 14 | 2,890
oligodendroglioma 14 | 2,850
pituitary cancer 14 | 1,972
Recurrent respiratory infections 12 | 141
Sinusitis 12 | 65
group 4 medulloblastoma 12 | 1,855
Cancer 11 | 2,499
Dull intelligence 11 | 645
Joubert syndrome 11 | 66
Low intelligence 11 | 645
Melanoma 11 | 711
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
Schizophrenia 11 | 1,160
cystic fibrosis and chronic rhinosinusitis 11 | 214
Alzheimer's disease 10 | 658
Bronchiectasis 10 | 64
Obesity 10 | 678
Retinitis Pigmentosa 10 | 226
pancreatic cancer 10 | 2,398
tuberculosis 10 | 2,010
Asphyxiating thoracic dystrophy 9 | 44
Bardet-Biedl syndrome 9 | 51
Endometrial cancer 9 | 311
Hydrocephalus 9 | 152
Nystagmus 9 | 317
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
invasive ductal carcinoma 9 | 2,951
Multiple myeloma 8 | 1,332
Situs ambiguus 8 | 25
Skin cancer 8 | 469
primary pancreatic ductal adenocarcinoma 8 | 1,109
Cataract 7 | 297
Congenital hypoplasia of penis 7 | 176
Electroretinogram abnormal 7 | 95
Epilepsy 7 | 792
Hypogonadism 7 | 173
Infertility 7 | 188
Lens Opacities 7 | 231
Meckel syndrome 7 | 46
Optic Atrophy 7 | 242
Short stature 7 | 531
colon cancer 7 | 1,478
cutaneous lupus erythematosus 7 | 1,057
diabetes mellitus 7 | 1,728
medulloblastoma 7 | 720
posterior fossa group B ependymoma 7 | 416
subependymal giant cell astrocytoma 7 | 2,287
DOID:2627 6 | 94
Fundus dystrophy 6 | 83
Meckel-Gruber syndrome 6 | 13
Multicystic Dysplastic Kidney 6 | 52
Orofaciodigital syndrome 6 | 21
Retinal Degeneration 6 | 106
Sensenbrenner syndrome 6 | 17
Short Rib-Polydactyly Syndrome 6 | 13
Ulnar polydactyly of fingers 6 | 47
adrenocortical carcinoma 6 | 1,428
cystic fibrosis 6 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
non primary Sjogren syndrome sicca 6 | 891
ulcerative colitis 6 | 1,819
Small head 5 | 374

Tissue

Endocrine System 141 | 18,159
Female tissues 134 | 17,400
Respiratory system 133 | 16,393
Male tissues 132 | 17,142
Skin and soft tissues 132 | 17,230
Digestive Tract 128 | 17,369
Nervous System 127 | 16,725
Urinary Tract 125 | 16,678
Liver and Pancreas 123 | 16,750
Blood and immune system 122 | 16,909
Cardiovascular System 103 | 15,192

Target Family

Non-IDG 123 | 12,091
Enzyme 14 | 4,145
Kinase 3 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

Axoneme 142 | 142
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cilia- and flagella-associated protein 74 CFAP74 Tdark Non-IDG 0.38 0.16 21
Oxygen-regulated protein 1 RP1 Tbio Non-IDG 0.30 0.88 40
Sperm flagellar protein 2 SPEF2 Tdark Non-IDG -1.20840 16.3 33
Dynein assembly factor 4, axonemal DNAAF4 Tbio Non-IDG -1.67209 48.6 216
Sperm flagellar protein 1 SPEF1 Tdark Non-IDG -0.39794 2.39 16
Tubulin monoglycylase TTLL3 TTLL3 Tbio Enzyme -0.53902 4.01 18
Outer dense fiber protein 3 ODF3 Tdark Non-IDG -0.68499 4.08 89
Protein tilB homolog LRRC6 Tbio Non-IDG -1.29587 19.2 150
Outer dense fiber protein 1 ODF1 Tdark Non-IDG -1.71715 50.2 33
Kinesin-like protein KIF3A KIF3A Tbio Non-IDG -2.06068 113.6 153