Development Level

Tbio 87 | 10,625
Tdark 39 | 7,003
Tchem 2 | 1,890
Tclin 1 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 8 | 633
preweaning lethality, incomple... 5 | 260
abnormal behavior 2 | 226
decreased body weight 2 | 174
embryonic lethality prior to t... 2 | 187
hyperactivity 2 | 108
abnormal cervical vertebrae mo... 1 | 4
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal response to tactile s... 1 | 16
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal tail movements 1 | 12
decreased B cell number 1 | 30
decreased circulating aspartat... 1 | 27
decreased circulating glucose ... 1 | 121
decreased circulating potassiu... 1 | 17
decreased grip strength 1 | 123
decreased lactate dehydrogenas... 1 | 14
decreased lumbar vertebrae num... 1 | 62
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
hypoactivity 1 | 89
increased body weight 1 | 42
increased circulating LDL chol... 1 | 15
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57

Disease

posterior fossa group B ependymoma 61 | 1,530
osteosarcoma 53 | 7,933
ovarian cancer 46 | 8,484
Primary ciliary dyskinesia 45 | 73
nasopharyngeal carcinoma 38 | 1,056
chronic rhinosinusitis 37 | 512
medulloblastoma, large-cell 34 | 6,234
psoriasis 34 | 6,685
Carcinoma 32 | 2,147
atypical teratoid / rhabdoid tumor 31 | 4,369
glioblastoma 30 | 5,572
Situs Inversus 26 | 48
Kartagener Syndrome 24 | 32
lung adenocarcinoma 23 | 2,713
ependymoma 19 | 2,514
lung cancer 19 | 4,466
lung carcinoma 18 | 2,844
Breast cancer 17 | 3,094
Ciliopathy 17 | 57
pilocytic astrocytoma 17 | 3,086
astrocytic glioma 16 | 2,241
adult high grade glioma 15 | 2,148
primitive neuroectodermal tumor 15 | 3,031
Male infertility 14 | 170
Polydactyly 14 | 93
medulloblastoma 14 | 1,524
Pick disease 13 | 1,893
Retinitis pigmentosa 12 | 153
group 3 medulloblastoma 12 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,956
group 4 medulloblastoma 11 | 1,875
malignant mesothelioma 11 | 3,162
non-small cell lung cancer 11 | 2,798
oligodendroglioma 11 | 2,849
pediatric high grade glioma 11 | 2,712
pituitary cancer 11 | 1,972
Nephronophthisis 10 | 74
cystic fibrosis and chronic rhinosinusitis 10 | 213
interstitial cystitis 9 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
invasive ductal carcinoma 9 | 2,950
Hydrocephalus 8 | 60
Cancer 7 | 2,346
Joubert syndrome 7 | 61
Kidney cancer 7 | 118
Multiple myeloma 7 | 1,327
atypical teratoid/rhabdoid tumor 7 | 1,095
primary pancreatic ductal adenocarcinoma 7 | 1,271
ulcerative colitis 7 | 2,087
Alzheimer's disease 6 | 644
Asphyxiating thoracic dystrophy 6 | 32
Bardet-Biedl Syndrome 6 | 40
Fundus dystrophy 6 | 77
Intellectual disability 6 | 573
Orofaciodigital syndrome 6 | 19
Rheumatoid Arthritis 6 | 1,160
cutaneous lupus erythematosus 6 | 1,056
progressive supranuclear palsy 6 | 674
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 1,557
Bronchiectasis 5 | 29
Ciliary Motility Disorders 5 | 6
Cone dystrophy 5 | 57
Obesity 5 | 616
adrenocortical carcinoma 5 | 1,427
colon cancer 5 | 1,475
fibroadenoma 5 | 557
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
pancreatic cancer 5 | 2,300
tuberculosis and treatment for 3 months 5 | 327
Atopic dermatitis 4 | 944
Cystic kidney disease 4 | 25
Jeune thoracic dystrophy 4 | 9
Meckel syndrome 4 | 48
Meckel-Gruber syndrome 4 | 15
Senior-Loken syndrome 4 | 21
Sensenbrenner syndrome 4 | 15
Sinusitis 4 | 30
astrocytoma 4 | 1,493
cystic fibrosis 4 | 1,665
diabetes mellitus 4 | 1,663
ductal carcinoma in situ 4 | 1,745
gastric cancer 4 | 430
gastric carcinoma 4 | 832
non primary Sjogren syndrome sicca 4 | 840
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
posterior fossa group A ependymoma 4 | 1,511
Ellis-Van Creveld syndrome 3 | 18
Infertility 3 | 163
Leber congenital amaurosis 3 | 72
Microcephaly 3 | 149
Neurodegenerative disease 3 | 383
Oculocerebrorenal syndrome 3 | 23
Polycystic kidney disease 3 | 54
Schizophrenia 3 | 501
active Crohn's disease 3 | 918
non-small cell lung carcinoma 3 | 413
spina bifida 3 | 1,064
tuberculosis and treatment for 6 months 3 | 686
urothelial carcinoma 3 | 318

Tissue

Female tissues 129 | 18,647
Male tissues 129 | 17,969
Nervous System 129 | 18,561
Digestive Tract 128 | 18,473
Endocrine System 128 | 18,512
Urinary Tract 128 | 18,444
Blood and immune system 127 | 17,995
Liver and Pancreas 127 | 18,136
Respiratory system 127 | 17,484
Cardiovascular System 126 | 17,958
Skin and soft tissues 126 | 18,115

Target Family

Non-IDG 110 | 11,971
Enzyme 14 | 4,146
Kinase 3 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

Axoneme 129 | 129
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centrosomal protein of 164 kDa CEP164 Tbio Non-IDG -0.96655 10.2 84
Bardet-Biedl syndrome 7 protein BBS7 Tbio Non-IDG -1.02867 11.1 125
Retinitis pigmentosa 1-like 1 protein RP1L1 Tbio Non-IDG -1.19453 19.3 0
Radial spoke head protein 6 homolog A RSPH6A Tdark Non-IDG -1.02050 11.1 25
Dynein regulatory complex subunit 3 DRC3 Tdark Non-IDG 0.60 0.47 21
Tctex1 domain-containing protein 3 TCTE3 Tdark Non-IDG -0.56557 4.53 21
Cilia- and flagella-associated protein 46 CFAP46 Tdark Non-IDG -0.17609 1.50 33
Tubulin--tyrosine ligase TTL Tchem Enzyme -1.29724 15.2 55
Transcription factor RFX3 RFX3 Tbio Transcription Factor -1.01621 10.4 134
Cilia- and flagella-associated protein 206 CFAP206 Tdark Non-IDG 0.00000 29