Development Level

Tbio 20 | 11,445
Tchem 4 | 1,598
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal bone structure 3 | 187
decreased lean body mass 3 | 135
decreased total body fat amoun... 3 | 207
increased circulating alkaline... 3 | 122
abnormal locomotor behavior 2 | 24
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
decreased pulmonary respirator... 2 | 5
enlarged stomach 2 | 2
impaired glucose tolerance 2 | 75
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
increased red blood cell distr... 2 | 34
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
small thymus 2 | 16
tremors 2 | 39
abnormal behavior 1 | 298
abnormal gait 1 | 69
abnormal nail morphology 1 | 8
abnormal sleep behavior 1 | 70
cataract 1 | 92
convulsive seizures 1 | 13
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased leukocyte cell numbe... 1 | 73
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
hypoactivity 1 | 132
increased circulating iron lev... 1 | 30
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 22 | 11,493
glioblastoma 18 | 5,792
adult high grade glioma 17 | 3,801
atypical teratoid / rhabdoid tumor 17 | 5,112
ependymoma 16 | 4,679
medulloblastoma, large-cell 16 | 6,241
oligodendroglioma 16 | 2,850
ovarian cancer 14 | 8,520
Astrocytoma, Pilocytic 13 | 3,081
astrocytic glioma 13 | 2,597
subependymal giant cell astrocytoma 12 | 2,287
Kidney cancer 11 | 2,613
lung cancer 11 | 4,740
psoriasis 11 | 6,694
osteosarcoma 10 | 7,950
primitive neuroectodermal tumor 10 | 3,035
Breast cancer 9 | 3,578
Schizophrenia 9 | 1,160
lung carcinoma 9 | 2,843
group 3 medulloblastoma 8 | 4,104
Cancer 7 | 2,499
Pick disease 7 | 1,894
Rheumatoid arthritis 7 | 1,191
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
invasive ductal carcinoma 7 | 2,951
Bipolar Disorder 6 | 666
colon cancer 6 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
malignant mesothelioma 6 | 3,232
pituitary cancer 6 | 1,972
Liver cancer 5 | 604
Neurodegenerative disease 5 | 414
interstitial cystitis 5 | 2,312
non-small cell lung cancer 5 | 2,890
ulcerative colitis 5 | 1,819
Down syndrome 4 | 499
Intellectual disability 4 | 1,016
Multiple Sclerosis 4 | 540
astrocytoma 4 | 1,146
group 4 medulloblastoma 4 | 1,855
hereditary spastic paraplegia 4 | 318
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
nasopharyngeal carcinoma 4 | 1,058
Alzheimer's disease 3 | 658
Autism spectrum disorder 3 | 101
Autistic Disorder 3 | 364
Colorectal cancer 3 | 25
Endometrial cancer 3 | 311
Endometriosis 3 | 540
Epilepsy 3 | 792
Gilles de la Tourette syndrome 3 | 47
Motor neuron disease 3 | 49
Vascular disease 3 | 319
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
medulloblastoma 3 | 720
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
Abnormality of the voice 2 | 46
Aphasia 2 | 26
Asperger syndrome 2 | 37
Attention deficit hyperactivity disorder 2 | 278
Autosomal recessive predisposition 2 | 1,442
Carcinoma, Renal Cell 2 | 124
Cerebrovascular disease 2 | 238
Congenital hypoplasia of breast 2 | 25
Congenital hypoplasia of penis 2 | 176
Decreased bone mineral density Z score 2 | 31
Decreased fertility 2 | 33
Delayed Puberty 2 | 97
Frontotemporal dementia 2 | 51
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Klinefelter's syndrome 2 | 56
Large intestine cancer 2 | 126
Major Depressive Disorder 2 | 301
Muscle hypotonia 2 | 571
Neurodevelopmental Disorders 2 | 70
Nicotine dependence 2 | 54
Obesity 2 | 678
Orofacial cleft 2 | 54
Pitt-Hopkins syndrome 2 | 20
Pitt-Hopkins-Like Syndrome 2 2 | 2
Prostatic Neoplasms 2 | 495
Renal Cell Carcinoma 2 | 214
Severe mental retardation (I.Q. 20-34) 2 | 99
Small testicle 2 | 75
Strabismus 2 | 270
Systemic lupus erythematosus 2 | 194
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
interstitial lung disease 2 | 298
pancreatic cancer 2 | 2,398
post-traumatic stress disorder 2 | 40
posterior fossa group B ependymoma 2 | 416
progressive supranuclear palsy 2 | 676
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Blood and immune system 24 | 16,909
Endocrine System 24 | 18,159
Nervous System 24 | 16,725
Digestive Tract 23 | 17,369
Female tissues 23 | 17,400
Male tissues 23 | 17,142
Liver and Pancreas 22 | 16,750
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 23 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

Compartment GO Term

Axonal growth cone 25 | 25
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Serine/threonine-protein kinase TAO2 TAOK2 Tchem Kinase -1.52454 36.1 154
Leucine-rich repeat transmembrane protein FLRT3 FLRT3 Tbio Non-IDG -1.29335 20.6 58
Down syndrome cell adhesion molecule DSCAM Tbio Non-IDG -2.12081 138.0 96
Oligodendrocyte-myelin glycoprotein OMG Tbio Non-IDG -2.22873 162.4 208
Neurexin-1-beta NRXN1 Tbio Non-IDG -1.88807 125.1 174
Semaphorin-4D SEMA4D Tbio Non-IDG -2.18250 176.3 525
Semaphorin-3A SEMA3A Tbio Non-IDG -2.70786 548.1 185
Semaphorin-3F SEMA3F Tbio Non-IDG -1.97011 94.5 125
Peptidyl-prolyl cis-trans isomerase FKBP4 FKBP4 Tchem Enzyme -2.69982 543.3 446