Development Level

Tbio 24 | 11,445
Tdark 6 | 6,588
Tchem 3 | 1,598

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased body weight 1 | 161
decreased circulating chloride... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
increased B cell number 1 | 9
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating serum al... 1 | 22
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96

Disease

Carcinoma 20 | 11,493
ovarian cancer 18 | 8,520
osteosarcoma 15 | 7,950
glioblastoma 11 | 5,792
medulloblastoma, large-cell 11 | 6,241
ependymoma 10 | 4,679
Astrocytoma, Pilocytic 8 | 3,081
lung cancer 8 | 4,740
psoriasis 8 | 6,694
subependymal giant cell astrocytoma 8 | 2,287
Cancer 7 | 2,499
adult high grade glioma 7 | 3,801
atypical teratoid / rhabdoid tumor 7 | 5,112
invasive ductal carcinoma 6 | 2,951
Multiple myeloma 5 | 1,332
malignant mesothelioma 5 | 3,232
pediatric high grade glioma 5 | 1,064
spina bifida 5 | 1,074
Breast cancer 4 | 3,578
Kidney cancer 4 | 2,613
Vici syndrome 4 | 14
astrocytic glioma 4 | 2,597
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
tuberculosis 4 | 2,010
Granulomatous amebic encephalitis 3 | 8
Schizophrenia 3 | 1,160
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
mucosa-associated lymphoid tissue lymphoma 3 | 484
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
sonic hedgehog group medulloblastoma 3 | 467
ulcerative colitis 3 | 1,819
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Atopic dermatitis 2 | 952
Cerebellar Ataxia 2 | 304
Colorectal Neoplasms 2 | 243
Crohn Disease 2 | 45
Crohn's disease 2 | 321
Fuchs' endothelial dystrophy 2 | 24
Inflammatory Bowel Diseases 2 | 35
Inflammatory bowel disease 2 | 151
Inflammatory bowel disease 5 2 | 14
Intellectual disability 2 | 1,016
Liver Cirrhosis, Experimental 2 | 769
Malaria 2 | 160
Neuropathy 2 | 261
Pick disease 2 | 1,894
Reflex, Deep Tendon, Absent 2 | 92
Rheumatoid arthritis 2 | 1,191
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
group 4 medulloblastoma 2 | 1,855
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
medulloblastoma 2 | 720
posterior fossa group B ependymoma 2 | 416
primitive neuroectodermal tumor 2 | 3,035
Acquired metabolic disease 1 | 336
Cardiovascular system disease 1 | 246
Charcot-Marie-Tooth disease 1 | 62
Chemical and Drug Induced Liver Injury 1 | 195
Common variable immunodeficiency 1 | 101
Congenital pes cavus 1 | 88
Distal amyotrophy 1 | 51
Downward slant of palpebral fissure 1 | 158
Gangliosidosis 1 | 20
Ichthyoses 1 | 41
Ichthyosis 1 | 56
Lymphoid leukemia 1 | 160
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO 1 | 11
Mucopolysaccharidosis III 1 | 7
Neurodegeneration with brain iron accumulation 5 1 | 9
Neuronal ceroid lipofuscinosis 8 northern epilepsy variant 1 | 6
Pachygyria 1 | 41
Polymicrogyria 1 | 48
Pontocerebellar hypoplasia 1 | 36
Renal Cell Carcinoma 1 | 214
Salivary Gland Neoplasms 1 | 46
Sensorineural Hearing Loss (disorder) 1 | 284
Severe mental retardation (I.Q. 20-34) 1 | 99
Usher syndrome type 1 1 | 10
Visual epilepsy 1 | 4
Vitiligo 1 | 73
posterior fossa group A ependymoma 1 | 468
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 32 | 16,909
Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Liver and Pancreas 32 | 16,750
Male tissues 32 | 17,142
Nervous System 32 | 16,725
Respiratory system 32 | 16,393
Skin and soft tissues 32 | 17,230
Urinary Tract 32 | 16,678
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 27 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634
Ion Channel 1 | 344

Compartment GO Term

Autophagosome membrane 33 | 33
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 74 TMEM74 Tdark Non-IDG -0.72496 3.54 52
Endophilin-B1 SH3GLB1 Tbio Non-IDG -1.10096 14.5 386
Autophagy-related protein 16-2 ATG16L2 Tbio Non-IDG -0.85199 7.18 135
Modulator of macroautophagy TMEM150B TMEM150B Tdark Non-IDG -0.08659 0.99 50
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248
Microtubule-associated proteins 1A/1B light chain 3 beta 2 MAP1LC3B2 Tdark Non-IDG -0.28657 1.04 24
Gamma-aminobutyric acid receptor-associated protein-like 1 GABARAPL1 Tbio Non-IDG -2.39692 232.7 211
WD repeat-containing protein 81 WDR81 Tbio Non-IDG -1.27329 20.6 5
Gamma-aminobutyric acid receptor-associated protein-like 3 GABARAPL3 Tdark Non-IDG -0.16137 0.12 0
Transmembrane 9 superfamily member 1 TM9SF1 Tdark Non-IDG -0.30160 1.84 172