Development Level

Tbio 84 | 11,445
Tchem 17 | 1,598
Tdark 10 | 6,588
Tclin 3 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased circulating LDL chol... 2 | 38
decreased grip strength 2 | 116
embryonic lethality prior to t... 2 | 278
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
prenatal lethality 2 | 28
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal epididymis morphology 1 | 42
abnormal retinal inner nuclear... 1 | 8
abnormal testis morphology 1 | 43
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
impaired glucose tolerance 1 | 75
increased B cell number 1 | 9
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating serum al... 1 | 22
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thrombocytopenia 1 | 56

Disease

Carcinoma 71 | 11,493
ovarian cancer 66 | 8,520
osteosarcoma 58 | 7,950
medulloblastoma, large-cell 43 | 6,241
glioblastoma 42 | 5,792
lung cancer 35 | 4,740
atypical teratoid / rhabdoid tumor 34 | 5,112
psoriasis 31 | 6,694
Cancer 29 | 2,499
adult high grade glioma 28 | 3,801
subependymal giant cell astrocytoma 26 | 2,287
ependymoma 23 | 4,679
malignant mesothelioma 23 | 3,232
Astrocytoma, Pilocytic 22 | 3,081
Neurodegenerative disease 21 | 414
invasive ductal carcinoma 20 | 2,951
diabetes mellitus 18 | 1,728
tuberculosis 18 | 2,010
Kidney cancer 17 | 2,613
Multiple myeloma 17 | 1,332
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
Breast cancer 16 | 3,578
Schizophrenia 16 | 1,160
group 4 medulloblastoma 15 | 1,855
non-small cell lung cancer 15 | 2,890
acute quadriplegic myopathy 14 | 1,158
breast carcinoma 14 | 1,638
group 3 medulloblastoma 14 | 4,104
primitive neuroectodermal tumor 14 | 3,035
Alzheimer's disease 13 | 658
astrocytic glioma 13 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
juvenile dermatomyositis 13 | 1,187
lung carcinoma 13 | 2,843
pancreatic cancer 13 | 2,398
dermatomyositis 12 | 966
oligodendroglioma 12 | 2,850
Parkinson's disease 11 | 392
Vascular disease 11 | 319
astrocytoma 11 | 1,146
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung adenocarcinoma 11 | 2,716
spina bifida 11 | 1,074
ulcerative colitis 11 | 1,819
Amyotrophic lateral sclerosis 10 | 451
Autosomal recessive predisposition 10 | 1,442
Dementia 10 | 175
Obesity 10 | 678
Rheumatoid arthritis 10 | 1,191
Toxic encephalopathy 10 | 141
Waldenstrons macroglobulinemia 10 | 765
Intellectual disability 9 | 1,016
Nerve Degeneration 9 | 121
Renal Cell Carcinoma 9 | 214
ductal carcinoma in situ 9 | 1,745
Vici syndrome 8 | 14
colon cancer 8 | 1,478
hepatocellular carcinoma 8 | 547
medulloblastoma 8 | 720
pediatric high grade glioma 8 | 1,064
pituitary cancer 8 | 1,972
Anemia 7 | 365
Depressive disorder 7 | 409
Kidney disease 7 | 430
Muscle Spasticity 7 | 195
Parkinsonian Disorders 7 | 56
Pick disease 7 | 1,894
mucosa-associated lymphoid tissue lymphoma 7 | 484
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Arthritis 6 | 290
Colorectal Neoplasms 6 | 243
Epilepsy 6 | 792
Huntington's disease 6 | 76
Neoplasm Invasiveness 6 | 161
Prostatic Neoplasms 6 | 495
active Crohn's disease 6 | 922
adrenocortical carcinoma 6 | 1,428
cystic fibrosis 6 | 1,696
posterior fossa group A ependymoma 6 | 468
Bipolar Disorder 5 | 666
Cataract 5 | 297
Cerebellar Ataxia 5 | 304
Cerebral atrophy 5 | 178
Duchenne muscular dystrophy 5 | 601
Endometrial cancer 5 | 311
Heart disease 5 | 306
Hyperreflexia 5 | 209
Inflammatory bowel disease 5 | 151
Liver cancer 5 | 604
Melanoma 5 | 711
Myopathy 5 | 185
Neuropathy 5 | 261
Paraplegia 5 | 74
Seizures 5 | 596
Stomach Neoplasms 5 | 300
gastric cancer 5 | 459
posterior fossa group B ependymoma 5 | 416
primary pancreatic ductal adenocarcinoma 5 | 1,109
progressive supranuclear palsy 5 | 676
sonic hedgehog group medulloblastoma 5 | 467

Tissue

Blood and immune system 110 | 16,909
Digestive Tract 110 | 17,369
Endocrine System 110 | 18,159
Female tissues 110 | 17,400
Liver and Pancreas 110 | 16,750
Male tissues 110 | 17,142
Nervous System 110 | 16,725
Respiratory system 110 | 16,393
Skin and soft tissues 110 | 17,230
Urinary Tract 110 | 16,678
Cardiovascular System 108 | 15,192

Target Family

Non-IDG 80 | 12,091
Enzyme 16 | 4,145
Kinase 14 | 634
Transcription Factor 2 | 1,400
Ion Channel 1 | 344
Transporter 1 | 473

Compartment GO Term

Autophagosome 114 | 114
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Ectopic P granules protein 5 homolog EPG5 Tbio Non-IDG -1.36198 23.3 33
Death-associated protein kinase 2 DAPK2 Tchem Kinase -1.39206 28.7 440
Transmembrane protein 74 TMEM74 Tdark Non-IDG -0.72496 3.54 52
Endophilin-B1 SH3GLB1 Tbio Non-IDG -1.10096 14.5 386
Microtubule-associated protein 1A MAP1A Tbio Non-IDG -1.95729 72.8 67
Ferritin light chain FTL Tbio Non-IDG -2.36162 227.3 549
Autophagy-related protein 16-2 ATG16L2 Tbio Non-IDG -0.85199 7.18 135
Modulator of macroautophagy TMEM150B TMEM150B Tdark Non-IDG -0.08659 0.99 50
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248