Development Level

Tbio 18 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 2 | 298
embryonic lethality prior to t... 2 | 278
increased mean corpuscular hem... 2 | 96
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
increased body length 1 | 32
increased circulating LDL chol... 1 | 13
increased circulating serum al... 1 | 22
increased lean body mass 1 | 172
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
premature death 1 | 5
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 16 | 8,520
Cancer 14 | 2,499
medulloblastoma, large-cell 14 | 6,241
Carcinoma 12 | 11,493
osteosarcoma 12 | 7,950
lung cancer 10 | 4,740
subependymal giant cell astrocytoma 9 | 2,287
Neurodegenerative disease 8 | 414
glioblastoma 8 | 5,792
psoriasis 8 | 6,694
Astrocytoma, Pilocytic 7 | 3,081
atypical teratoid / rhabdoid tumor 7 | 5,112
Kidney cancer 6 | 2,613
adult high grade glioma 6 | 3,801
Breast cancer 5 | 3,578
Multiple myeloma 5 | 1,332
Renal Cell Carcinoma 5 | 214
Vascular disease 5 | 319
Waldenstrons macroglobulinemia 5 | 765
dermatomyositis 5 | 966
group 3 medulloblastoma 5 | 4,104
hepatocellular carcinoma 5 | 547
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
Schizophrenia 4 | 1,160
acute quadriplegic myopathy 4 | 1,158
diabetes mellitus 4 | 1,728
ependymoma 4 | 4,679
gastric cancer 4 | 459
group 4 medulloblastoma 4 | 1,855
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Anemia 3 | 365
Carcinoma, Renal Cell 3 | 124
Depressive disorder 3 | 409
Highly variable clinical phenotype 3 | 150
Highly variable phenotype and severity 3 | 150
Highly variable phenotype, even within families 3 | 150
Muscle Spasticity 3 | 195
Neoplasm Invasiveness 3 | 161
Nerve Degeneration 3 | 121
Neurodegenerative Disorders 3 | 79
Obesity 3 | 678
Ovarian Neoplasms 3 | 102
Phenotypic variability 3 | 150
Pick disease 3 | 1,894
Status Epilepticus 3 | 98
Toxic encephalopathy 3 | 141
Vici syndrome 3 | 14
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
mucosa-associated lymphoid tissue lymphoma 3 | 484
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Abnormality of metabolism/homeostasis 2 | 134
Carcinoma, Hepatocellular 2 | 228
Cardiomyopathy 2 | 116
Cerebral atrophy 2 | 178
Chemical and Drug Induced Liver Injury 2 | 195
Common variable immunodeficiency 2 | 101
Connective tissue disease 2 | 62
Crohn's disease 2 | 321
Degenerative polyarthritis 2 | 115
Deglutition Disorders 2 | 132
Dementia 2 | 175
Down syndrome 2 | 499
Dysarthria 2 | 192
Endometriosis 2 | 540
Hyperreflexia 2 | 209
Large intestine cancer 2 | 126
Lethargy 2 | 77
Liver carcinoma 2 | 240
Lymphopenia 2 | 67
Malaria 2 | 160
Mood swings 2 | 77
Necrosis 2 | 53
Neuro-degenerative disease 2 | 43
Osteoarthritis 2 | 184
Parkinson's disease 2 | 392
Parkinsonian Disorders 2 | 56
Progressive disorder 2 | 142
Respiratory Failure 2 | 104
Retinal Degeneration 2 | 106
Social disinhibition 2 | 14
Weight Loss 2 | 24
Weight decreased 2 | 103
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562

Tissue

Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678

Target Family

Non-IDG 17 | 12,091
Kinase 4 | 634
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

Compartment GO Term

Autolysosome 23 | 23
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ectopic P granules protein 5 homolog EPG5 Tbio Non-IDG -1.36198 23.3 33
Microtubule-associated protein 1A MAP1A Tbio Non-IDG -1.95729 72.8 67
Ferritin light chain FTL Tbio Non-IDG -2.36162 227.3 549
Gamma-aminobutyric acid receptor-associated protein-like 1 GABARAPL1 Tbio Non-IDG -2.39692 232.7 211
Autophagy-related protein 16-1 ATG16L1 Tbio Non-IDG -2.26343 183.4 600
Cathepsin D CTSD Tchem Enzyme -3.47061 2866.8 779
Sequestosome-1 SQSTM1 Tbio Non-IDG -2.78728 635.1 766
Nuclear receptor coactivator 4 NCOA4 Tbio Non-IDG -2.20245 136.0 283
Ferritin heavy chain FTH1 Tbio Non-IDG -3.00480 982.1 562
Lysosome-associated membrane glycoprotein 2 LAMP2 Tbio Non-IDG -2.57929 343.7 905