Development Level

Tbio 4 | 11,445

IMPC Phenotype

decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
increased heart weight 1 | 62

Disease

glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
Epilepsy 3 | 792
Multiple Sclerosis 3 | 540
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
Astrocytoma, Pilocytic 2 | 3,081
Brain Ischemia 2 | 110
Brain disease 2 | 96
Carcinoma 2 | 11,493
Cerebrovascular disease 2 | 238
Depressive disorder 2 | 409
Disease Models, Animal 2 | 155
Down syndrome 2 | 499
Hydrocephalus 2 | 152
Major Depressive Disorder 2 | 301
Mental Depression 2 | 333
Neuromyelitis optica 2 | 18
Parkinson Disease 2 | 64
Parkinson's disease 2 | 392
Seizures 2 | 596
Unipolar Depression 2 | 250
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
osteosarcoma 2 | 7,950
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Adenocarcinoma of lung 1 | 142
Alcoholic Intoxication, Chronic 1 | 289
Alexander disease 1 | 11
Amyotrophic lateral sclerosis 1 | 451
Ankle clonus 1 | 6
Ataxia, Truncal 1 | 21
Autistic Disorder 1 | 364
Babinski Reflex 1 | 100
Brain Edema 1 | 50
Broad-based gait 1 | 19
Cerebrospinal fluid protein increased above normal 1 | 14
Choroid Plexus Papilloma 1 | 10
Common variable immunodeficiency 1 | 101
Dementia 1 | 175
Developmental regression 1 | 95
Dysmyelination of the brain 1 | 6
Encephalitis 1 | 64
Esotropia 1 | 31
Exotropia 1 | 35
Eye disease 1 | 62
Ganglioglioma 1 | 13
Gliosis 1 | 56
Huntington's disease 1 | 76
Hyperalgesia 1 | 83
Hyperreflexia 1 | 209
Hypoplasia of the brainstem 1 | 22
Infantile onset 1 | 238
Intracranial hypertension 1 | 32
Language Disorders 1 | 13
Leukodystrophy 1 | 55
Lewy Body Disease 1 | 21
Lissencephaly 1 | 69
Loss of developmental milestones 1 | 95
Mental deterioration in childhood 1 | 95
Muscle Hypertonia 1 | 88
Muscle Spasticity 1 | 195
Nephrogenic Diabetes Insipidus 1 | 16
Nerve Degeneration 1 | 121
Nervous System Diseases 1 | 53
Neurilemmoma 1 | 23
Neuroblastoma 1 | 80
Neurodegenerative disease 1 | 414
Neurodevelopmental regression 1 | 95
POLYMICROGYRIA, BILATERAL FRONTOPARIETAL 1 | 1
Parkinsonian Disorders 1 | 56
Peripheral Neuropathy 1 | 134
Periventricular nodular heterotopia 1 | 30
Pleomorphic adenoma 1 | 18
Polymicrogyria, Bilateral Perisylvian, Autosomal Recessive 1 | 1
Polymicrogyria, anterior to posterior gradient 1 | 1
Polymicrogyria, frontoparietal 1 | 2
Polymicrogyria, perisylvian 1 | 1
Progressive macrocephaly 1 | 18
Psychomotor regression 1 | 95
Psychomotor regression beginning in infancy 1 | 95
Psychomotor regression in infants 1 | 95
Psychomotor regression, progressive 1 | 95
Retinal disease 1 | 25
Status Epilepticus 1 | 98
Toxic encephalopathy 1 | 141
Trigeminal Neuralgia 1 | 24
White matter dysmyelination/demyelination 1 | 6
inflammatory breast cancer 1 | 286
nervous system disorder 1 | 53
permanent atrial fibrillation 1 | 45
tuberculosis 1 | 2,010
type I diabetes mellitus 1 | 22

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 2 | 12,091
GPCR 1 | 408
Kinase 1 | 634

Compartment GO Term

Astrocyte projection 4 | 4
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Aquaporin-4 AQP4 Tbio Non-IDG -3.33435 2159.1 358
Glial fibrillary acidic protein GFAP Tbio Non-IDG -3.50578 2828.7 1992
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546