Development Level

Tbio 161 | 11,445
Tchem 33 | 1,598
Tclin 26 | 613
Tdark 15 | 6,588

Collection

RFA-RM-18-021 5 | 328
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 19 | 979
abnormal bone structure 9 | 187
decreased total body fat amoun... 7 | 207
increased startle reflex 7 | 112
abnormal retina morphology 6 | 71
decreased grip strength 6 | 116
embryonic lethality prior to o... 6 | 239
decreased bone mineral content 5 | 151
embryonic lethality prior to t... 5 | 278
increased blood urea nitrogen ... 5 | 48
increased heart weight 5 | 62
increased lean body mass 5 | 172
abnormal behavior 4 | 298
decreased body weight 4 | 161
decreased startle reflex 4 | 75
hypoactivity 4 | 132
increased circulating HDL chol... 4 | 80
increased circulating total pr... 4 | 28
increased or absent threshold ... 4 | 101
preweaning lethality, incomple... 4 | 499
abnormal pelvic girdle bone mo... 3 | 12
abnormal vibrissa morphology 3 | 25
decreased body length 3 | 101
decreased circulating choleste... 3 | 93
decreased circulating glucose ... 3 | 126
decreased hemoglobin content 3 | 68
decreased vertical activity 3 | 208
enlarged heart 3 | 210
impaired glucose tolerance 3 | 75
increased circulating alkaline... 3 | 122
increased circulating calcium ... 3 | 34
increased circulating creatini... 3 | 38
increased circulating iron lev... 3 | 30
abnormal embryo size 2 | 220
abnormal embryo turning 2 | 31
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal pericardium morpholog... 2 | 26
abnormal sleep behavior 2 | 70
abnormal snout morphology 2 | 23
abnormal vertebrae morphology 2 | 18
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating triglyce... 2 | 79
decreased eosinophil cell numb... 2 | 24
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular vol... 2 | 79
decreased mean platelet volume 2 | 25
decreased prepulse inhibition 2 | 82
embryonic growth retardation 2 | 106
improved glucose tolerance 2 | 79
increased anti-nuclear antigen... 2 | 19
increased circulating choleste... 2 | 66
increased circulating serum al... 2 | 22
increased circulating sodium l... 2 | 71
increased grip strength 2 | 41
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal hair growth 1 | 10
abnormal head morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal retinal blood vessel ... 1 | 26
abnormal tail movements 1 | 12
abnormal vitelline vasculature... 1 | 6
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
absent vibrissae 1 | 12
cataract 1 | 92
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased food intake 1 | 13
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
impaired righting response 1 | 26
increased body weight 1 | 25
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
shortened PQ interval 1 | 7

Disease

Carcinoma 182 | 11,493
psoriasis 107 | 6,694
ovarian cancer 105 | 8,520
osteosarcoma 97 | 7,950
lung cancer 82 | 4,740
medulloblastoma, large-cell 79 | 6,241
glioblastoma 72 | 5,792
ependymoma 70 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 68 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 66 | 3,291
non-small cell lung cancer 65 | 2,890
Cancer 62 | 2,499
Breast cancer 60 | 3,578
Kidney cancer 60 | 2,613
lung adenocarcinoma 56 | 2,716
malignant mesothelioma 56 | 3,232
pancreatic cancer 56 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 55 | 2,989
lung carcinoma 55 | 2,843
atypical teratoid / rhabdoid tumor 54 | 5,112
Autosomal recessive predisposition 50 | 1,442
invasive ductal carcinoma 50 | 2,951
interstitial cystitis 48 | 2,312
Astrocytoma, Pilocytic 46 | 3,081
adult high grade glioma 46 | 3,801
group 3 medulloblastoma 46 | 4,104
pituitary cancer 45 | 1,972
Kidney disease 43 | 430
cystic fibrosis 41 | 1,696
ulcerative colitis 41 | 1,819
oligodendroglioma 39 | 2,850
ductal carcinoma in situ 37 | 1,745
astrocytic glioma 33 | 2,597
colon cancer 33 | 1,478
diabetes mellitus 32 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,962
Hypertension 29 | 396
subependymal giant cell astrocytoma 29 | 2,287
breast carcinoma 27 | 1,638
nasopharyngeal carcinoma 27 | 1,058
primitive neuroectodermal tumor 27 | 3,035
tuberculosis 27 | 2,010
Schizophrenia 26 | 1,160
esophageal adenocarcinoma 25 | 737
active Crohn's disease 24 | 922
spina bifida 24 | 1,074
Diarrhea 23 | 253
Intellectual disability 22 | 1,016
active ulcerative colitis 22 | 764
Epilepsy 21 | 792
Melanoma 21 | 711
Pick disease 21 | 1,894
group 4 medulloblastoma 21 | 1,855
nephrosclerosis 21 | 333
Skin cancer 20 | 469
adrenocortical carcinoma 20 | 1,428
Dull intelligence 19 | 645
Liver Cirrhosis, Experimental 19 | 769
Liver cancer 19 | 604
Low intelligence 19 | 645
Mental Retardation 19 | 645
Mental deficiency 19 | 645
Poor school performance 19 | 645
Rheumatoid arthritis 19 | 1,191
cutaneous lupus erythematosus 19 | 1,057
acute quadriplegic myopathy 18 | 1,158
dermatomyositis 18 | 966
gastric carcinoma 18 | 807
juvenile dermatomyositis 18 | 1,187
primary pancreatic ductal adenocarcinoma 18 | 1,109
pediatric high grade glioma 17 | 1,064
Anemia 16 | 365
Down syndrome 16 | 499
Failure to gain weight 16 | 365
Obesity 16 | 678
Pediatric failure to thrive 16 | 365
chronic rhinosinusitis 16 | 512
Hypertensive disease 15 | 292
Metabolic acidosis 15 | 90
Osteoporosis 15 | 363
aldosterone-producing adenoma 15 | 665
non primary Sjogren syndrome sicca 15 | 891
Endometriosis 14 | 540
Prostatic Neoplasms 14 | 495
Seizures 14 | 596
Atherosclerosis 13 | 291
Breast Neoplasms 13 | 445
Constipation 13 | 181
Coronary artery disease 13 | 268
Liver disease 13 | 237
Mammary Neoplasms 13 | 425
Multiple myeloma 13 | 1,332
urothelial carcinoma 13 | 318
Alzheimer's disease 12 | 658
Asthma 12 | 385
Cataract 12 | 297
Hyperuricemia 12 | 49
Short stature 12 | 531
astrocytoma 12 | 1,146
progressive supranuclear palsy 12 | 676

Tissue

Endocrine System 225 | 18,159
Digestive Tract 219 | 17,369
Male tissues 217 | 17,142
Urinary Tract 217 | 16,678
Liver and Pancreas 214 | 16,750
Female tissues 212 | 17,400
Skin and soft tissues 212 | 17,230
Blood and immune system 208 | 16,909
Nervous System 204 | 16,725
Respiratory system 199 | 16,393
Cardiovascular System 170 | 15,192

Target Family

Non-IDG 115 | 12,091
Transporter 56 | 473
Enzyme 36 | 4,145
Ion Channel 15 | 344
Kinase 7 | 634
GPCR 6 | 408

Compartment GO Term

Apical plasma membrane 235 | 235
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adherens junction-associated protein 1 AJAP1 Tbio Non-IDG -1.20907 21.2 25
TRAF2 and NCK-interacting protein kinase TNIK Tchem Kinase -1.33394 28.5 441
Potassium voltage-gated channel subfamily C member 2 KCNC2 Tclin Ion Channel -1.45272 28.7 178
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Protein Shroom2 SHROOM2 Tbio Non-IDG -1.07032 11.9 112
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
Solute carrier family 12 member 1 SLC12A1 Tclin Transporter -2.37125 226.3 178
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.90516 156.1 254
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303