Development Level

Tbio 203 | 10,625
Tchem 75 | 1,890
Tclin 33 | 602
Tdark 20 | 7,003

Collection

Eligible Ion Channel Proteins 4 | 117
Eligible non-olfactory GPCR Proteins 2 | 143

IMPC Term

preweaning lethality, complete... 19 | 633
abnormal bone structure 8 | 131
decreased bone mineral content 8 | 157
decreased total body fat amoun... 8 | 186
abnormal retina morphology 7 | 100
decreased lean body mass 7 | 195
abnormal bone mineralization 6 | 55
decreased bone mineral density 6 | 126
decreased grip strength 6 | 123
increased blood urea nitrogen ... 6 | 44
increased grip strength 6 | 83
abnormal behavior 5 | 226
abnormal retinal pigmentation 5 | 61
decreased body weight 5 | 174
embryonic lethality prior to t... 5 | 187
hypoactivity 5 | 89
increased body weight 5 | 42
increased or absent threshold ... 5 | 128
decreased body length 4 | 108
decreased circulating HDL chol... 4 | 77
decreased circulating choleste... 4 | 85
decreased circulating glucose ... 4 | 121
decreased circulating triglyce... 4 | 83
increased circulating alkaline... 4 | 119
increased heart weight 4 | 37
abnormal kidney morphology 3 | 30
abnormal pelvic girdle bone mo... 3 | 11
decreased circulating insulin ... 3 | 75
decreased startle reflex 3 | 48
embryonic lethality prior to o... 3 | 148
enlarged heart 3 | 111
impaired glucose tolerance 3 | 52
improved glucose tolerance 3 | 56
increased B cell number 3 | 23
increased circulating HDL chol... 3 | 63
increased circulating creatini... 3 | 29
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 107
increased mean corpuscular vol... 3 | 91
preweaning lethality, incomple... 3 | 260
abnormal cornea morphology 2 | 24
abnormal seminal vesicle morph... 2 | 47
abnormal vibrissa morphology 2 | 17
corneal opacity 2 | 25
decreased circulating free fat... 2 | 39
decreased eosinophil cell numb... 2 | 41
decreased fasted circulating g... 2 | 49
decreased hemoglobin content 2 | 53
decreased prepulse inhibition 2 | 52
decreased rib number 2 | 59
decreased spleen weight 2 | 13
impaired righting response 2 | 19
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating choleste... 2 | 53
increased circulating potassiu... 2 | 31
increased circulating total pr... 2 | 20
increased leukocyte cell numbe... 2 | 37
increased mean platelet volume 2 | 19
increased plasma cell number 2 | 5
increased rib number 2 | 41
increased total body fat amoun... 2 | 57
limb grasping 2 | 35
trunk curl 2 | 15
abnormal coat appearance 1 | 25
abnormal ear morphology 1 | 5
abnormal eye morphology 1 | 38
abnormal heart morphology 1 | 51
abnormal respiratory quotient 1 | 9
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
abnormal thoracic vertebrae mo... 1 | 16
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 21
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating chloride... 1 | 32
decreased circulating potassiu... 1 | 17
decreased effector memory CD8-... 1 | 24
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased vertical activity 1 | 22
female infertility 1 | 34
increased circulating alanine ... 1 | 11
increased circulating amylase ... 1 | 13
increased circulating iron lev... 1 | 25
increased circulating triglyce... 1 | 24
increased eosinophil cell numb... 1 | 9
increased startle reflex 1 | 38
persistence of hyaloid vascula... 1 | 22
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
shortened ST segment 1 | 9
stereotypic behavior 1 | 3
straub tail 1 | 26
tremors 1 | 34
vertebral fusion 1 | 23

Disease

psoriasis 150 | 6,685
osteosarcoma 143 | 7,933
ovarian cancer 141 | 8,484
lung cancer 111 | 4,466
Cancer 106 | 2,346
medulloblastoma, large-cell 100 | 6,234
intraductal papillary-mucinous adenoma (IPMA) 98 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 98 | 3,289
glioblastoma 88 | 5,572
non-small cell lung cancer 86 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 85 | 2,988
Carcinoma 81 | 2,147
pancreatic cancer 81 | 2,300
lung adenocarcinoma 78 | 2,713
malignant mesothelioma 77 | 3,162
lung carcinoma 73 | 2,844
Breast cancer 71 | 3,094
atypical teratoid / rhabdoid tumor 69 | 4,369
interstitial cystitis 69 | 2,299
ulcerative colitis 69 | 2,087
cystic fibrosis 64 | 1,665
invasive ductal carcinoma 63 | 2,950
pituitary cancer 62 | 1,972
Kidney disease 54 | 396
pilocytic astrocytoma 54 | 3,086
ductal carcinoma in situ 51 | 1,745
pediatric high grade glioma 51 | 2,712
diabetes mellitus 48 | 1,663
oligodendroglioma 48 | 2,849
colon cancer 45 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 42 | 1,795
subependymal giant cell astrocytoma 42 | 2,287
ependymoma 41 | 2,514
primitive neuroectodermal tumor 41 | 3,031
esophageal adenocarcinoma 40 | 737
active Crohn's disease 39 | 918
tuberculosis 39 | 1,557
Hypertension 38 | 287
astrocytic glioma 38 | 2,241
Rheumatoid Arthritis 34 | 1,160
adult high grade glioma 34 | 2,148
nasopharyngeal carcinoma 34 | 1,056
primary pancreatic ductal adenocarcinoma 34 | 1,271
posterior fossa group A ependymoma 33 | 1,511
group 3 medulloblastoma 32 | 2,254
adrenocortical carcinoma 31 | 1,427
cutaneous lupus erythematosus 31 | 1,056
Diarrhea 30 | 155
Obesity 30 | 616
breast carcinoma 30 | 1,614
Mammary Neoplasms 29 | 410
Pick disease 29 | 1,893
nephrosclerosis 29 | 329
posterior fossa group B ependymoma 29 | 1,530
spina bifida 29 | 1,064
Cholestasis 28 | 93
Prostatic Neoplasms 28 | 471
Coronary artery disease 27 | 240
Liver disease 27 | 219
gastric carcinoma 27 | 832
group 4 medulloblastoma 25 | 1,875
Down syndrome 24 | 548
Endometriosis 24 | 535
Alzheimer's disease 23 | 644
Heart disease 23 | 279
Hypertensive disease 23 | 193
Metabolic acidosis 23 | 49
medulloblastoma 23 | 1,524
Cerebrovascular disease 22 | 231
astrocytoma 22 | 1,493
atypical teratoid/rhabdoid tumor 22 | 1,095
Atherosclerosis 21 | 275
Inflammatory bowel disease 21 | 142
sonic hedgehog group medulloblastoma 21 | 1,482
Anemia 20 | 252
Osteoporosis 20 | 257
active ulcerative colitis 20 | 477
acute quadriplegic myopathy 20 | 1,157
chronic rhinosinusitis 20 | 512
Asthma 18 | 349
non primary Sjogren syndrome sicca 18 | 840
progressive supranuclear palsy 18 | 674
Multiple myeloma 17 | 1,327
dermatomyositis 17 | 933
juvenile dermatomyositis 17 | 1,189
urothelial carcinoma 17 | 318
Adenoma 16 | 165
Epilepsy 16 | 346
Multiple Sclerosis 16 | 498
Peripheral Neuropathy 16 | 303
Schizophrenia 16 | 501
aldosterone-producing adenoma 16 | 664
sarcoidosis 16 | 358
Colorectal Neoplasms 15 | 217
Edema 15 | 38
Hypersensitivity reaction type II disease 15 | 235
Hypokalemia 15 | 40
Barrett's esophagus 14 | 183
Hypothyroidism 14 | 89
mucosa-associated lymphoid tissue lymphoma 14 | 480

Tissue

Digestive Tract 323 | 18,473
Female tissues 323 | 18,647
Nervous System 323 | 18,561
Endocrine System 322 | 18,512
Liver and Pancreas 322 | 18,136
Urinary Tract 322 | 18,444
Blood and immune system 320 | 17,995
Cardiovascular System 317 | 17,958
Male tissues 317 | 17,969
Skin and soft tissues 317 | 18,115
Respiratory system 310 | 17,484

Target Family

Non-IDG 162 | 11,971
Transporter 80 | 473
Enzyme 42 | 4,146
Ion Channel 23 | 341
GPCR 9 | 406
Kinase 9 | 634
Transcription Factor 6 | 1,400

Compartment GO Term

Apical part of cell 331 | 331
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Teratocarcinoma-derived growth factor 1 TDGF1 Tbio Non-IDG 156.3 371
N-acetylated-alpha-linked acidic dipeptidase-like protein NAALADL1 Tbio Enzyme -1.30374 25.3 78
Equilibrative nucleoside transporter 4 SLC29A4 Tbio Transporter -1.79381 73.1 189
Sodium/hydrogen exchanger 4 SLC9A4 Tdark Transporter -1.25841 17.4 6
Ileal sodium/bile acid cotransporter SLC10A2 Tchem Transporter -2.60727 417.5 121
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Otoancorin OTOA Tdark Non-IDG -1.29628 19.3 48
Solute carrier family 26 member 9 SLC26A9 Tbio Transporter -1.20448 19.3 27
Adenosylhomocysteinase 2 AHCYL1 Tchem Enzyme -1.57893 43.2 102