Development Level

Tbio 203 | 10,625
Tchem 75 | 1,890
Tclin 33 | 602
Tdark 20 | 7,003

Collection

Ion Channel: IDG Consortium (Targets) 4 | 102
GPCR: IDG Consortium (Targets) 2 | 128
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 19 | 633
abnormal bone structure 8 | 131
decreased bone mineral content 8 | 157
decreased total body fat amoun... 8 | 186
abnormal retina morphology 7 | 100
decreased lean body mass 7 | 195
abnormal bone mineralization 6 | 55
decreased bone mineral density 6 | 126
decreased grip strength 6 | 123
increased blood urea nitrogen ... 6 | 44
increased grip strength 6 | 83
abnormal behavior 5 | 226
abnormal retinal pigmentation 5 | 61
decreased body weight 5 | 174
embryonic lethality prior to t... 5 | 187
hypoactivity 5 | 89
increased body weight 5 | 42
increased or absent threshold ... 5 | 128
decreased body length 4 | 108
decreased circulating HDL chol... 4 | 77
decreased circulating choleste... 4 | 85
decreased circulating glucose ... 4 | 121
decreased circulating triglyce... 4 | 83
increased circulating alkaline... 4 | 119
increased heart weight 4 | 37
abnormal kidney morphology 3 | 30
abnormal pelvic girdle bone mo... 3 | 11
decreased circulating insulin ... 3 | 75
decreased startle reflex 3 | 48
embryonic lethality prior to o... 3 | 148
enlarged heart 3 | 111
impaired glucose tolerance 3 | 52
improved glucose tolerance 3 | 56
increased B cell number 3 | 23
increased circulating HDL chol... 3 | 63
increased circulating creatini... 3 | 29
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 107
increased mean corpuscular vol... 3 | 91
preweaning lethality, incomple... 3 | 260
abnormal cornea morphology 2 | 24
abnormal seminal vesicle morph... 2 | 47
abnormal vibrissa morphology 2 | 17
corneal opacity 2 | 25
decreased circulating free fat... 2 | 39
decreased eosinophil cell numb... 2 | 41
decreased fasted circulating g... 2 | 49
decreased hemoglobin content 2 | 53
decreased prepulse inhibition 2 | 52
decreased rib number 2 | 59
decreased spleen weight 2 | 13
impaired righting response 2 | 19
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating choleste... 2 | 53
increased circulating potassiu... 2 | 31
increased circulating total pr... 2 | 20
increased leukocyte cell numbe... 2 | 37
increased mean platelet volume 2 | 19
increased plasma cell number 2 | 5
increased rib number 2 | 41
increased total body fat amoun... 2 | 57
limb grasping 2 | 35
trunk curl 2 | 15
abnormal coat appearance 1 | 25
abnormal ear morphology 1 | 5
abnormal eye morphology 1 | 38
abnormal heart morphology 1 | 51
abnormal respiratory quotient 1 | 9
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
abnormal thoracic vertebrae mo... 1 | 16
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 21
decreased blood urea nitrogen ... 1 | 31
decreased caudal vertebrae num... 1 | 49
decreased circulating chloride... 1 | 32
decreased circulating potassiu... 1 | 17
decreased effector memory CD8-... 1 | 24
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased vertical activity 1 | 22
female infertility 1 | 34
increased circulating alanine ... 1 | 11
increased circulating amylase ... 1 | 13
increased circulating iron lev... 1 | 25
increased circulating triglyce... 1 | 24
increased eosinophil cell numb... 1 | 9
increased startle reflex 1 | 38
persistence of hyaloid vascula... 1 | 22
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
shortened ST segment 1 | 9
stereotypic behavior 1 | 3
straub tail 1 | 26
tremors 1 | 34
vertebral fusion 1 | 23

Disease

psoriasis 150 | 6,685
osteosarcoma 143 | 7,933
ovarian cancer 141 | 8,491
lung cancer 112 | 4,473
Cancer 106 | 2,346
medulloblastoma, large-cell 100 | 6,234
intraductal papillary-mucinous adenoma (IPMA) 98 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 98 | 3,289
glioblastoma 88 | 5,572
non-small cell lung cancer 86 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 85 | 2,988
Carcinoma 81 | 2,147
pancreatic cancer 81 | 2,300
lung adenocarcinoma 78 | 2,714
malignant mesothelioma 77 | 3,163
lung carcinoma 73 | 2,844
Breast cancer 71 | 3,098
atypical teratoid / rhabdoid tumor 69 | 4,369
interstitial cystitis 69 | 2,299
ulcerative colitis 69 | 2,087
cystic fibrosis 65 | 1,670
invasive ductal carcinoma 63 | 2,950
pituitary cancer 62 | 1,972
Kidney disease 54 | 397
pilocytic astrocytoma 54 | 3,086
ductal carcinoma in situ 51 | 1,745
pediatric high grade glioma 51 | 2,712
diabetes mellitus 48 | 1,663
oligodendroglioma 48 | 2,849
colon cancer 45 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 42 | 1,795
subependymal giant cell astrocytoma 42 | 2,287
ependymoma 41 | 2,514
primitive neuroectodermal tumor 41 | 3,031
esophageal adenocarcinoma 40 | 737
Hypertension 39 | 293
active Crohn's disease 39 | 918
tuberculosis 39 | 1,563
astrocytic glioma 38 | 2,241
Rheumatoid Arthritis 34 | 1,170
adult high grade glioma 34 | 2,148
nasopharyngeal carcinoma 34 | 1,056
primary pancreatic ductal adenocarcinoma 34 | 1,271
posterior fossa group A ependymoma 33 | 1,511
group 3 medulloblastoma 32 | 2,254
adrenocortical carcinoma 31 | 1,427
cutaneous lupus erythematosus 31 | 1,056
Diarrhea 30 | 155
Obesity 30 | 616
breast carcinoma 30 | 1,614
Mammary Neoplasms 29 | 410
Pick disease 29 | 1,893
nephrosclerosis 29 | 329
posterior fossa group B ependymoma 29 | 1,530
spina bifida 29 | 1,064
Cholestasis 28 | 93
Prostatic Neoplasms 28 | 471
Coronary artery disease 27 | 240
Liver disease 27 | 219
gastric carcinoma 27 | 832
group 4 medulloblastoma 25 | 1,875
Down syndrome 24 | 548
Endometriosis 24 | 535
Alzheimer's disease 23 | 644
Heart disease 23 | 279
Hypertensive disease 23 | 193
Metabolic acidosis 23 | 49
medulloblastoma 23 | 1,524
Cerebrovascular disease 22 | 231
astrocytoma 22 | 1,493
atypical teratoid/rhabdoid tumor 22 | 1,095
Atherosclerosis 21 | 275
Inflammatory bowel disease 21 | 142
sonic hedgehog group medulloblastoma 21 | 1,482
Anemia 20 | 252
Osteoporosis 20 | 259
active ulcerative colitis 20 | 477
acute quadriplegic myopathy 20 | 1,157
chronic rhinosinusitis 20 | 512
Asthma 18 | 349
non primary Sjogren syndrome sicca 18 | 840
progressive supranuclear palsy 18 | 674
Multiple myeloma 17 | 1,327
dermatomyositis 17 | 966
juvenile dermatomyositis 17 | 1,189
urothelial carcinoma 17 | 318
Adenoma 16 | 165
Epilepsy 16 | 346
Multiple Sclerosis 16 | 498
Peripheral Neuropathy 16 | 303
Schizophrenia 16 | 503
aldosterone-producing adenoma 16 | 664
sarcoidosis 16 | 368
Colorectal Neoplasms 15 | 217
Edema 15 | 38
Hypersensitivity reaction type II disease 15 | 235
Hypokalemia 15 | 40
Polycystic Ovary Syndrome 15 | 334
Hypothyroidism 14 | 89
mucosa-associated lymphoid tissue lymphoma 14 | 480

Tissue

Digestive Tract 323 | 18,472
Female tissues 323 | 18,646
Nervous System 323 | 18,560
Endocrine System 322 | 18,511
Liver and Pancreas 322 | 18,135
Urinary Tract 322 | 18,443
Blood and immune system 320 | 17,994
Cardiovascular System 317 | 17,957
Male tissues 317 | 17,968
Skin and soft tissues 317 | 18,114
Respiratory system 310 | 17,483

Target Family

Non-IDG 162 | 11,969
Transporter 80 | 473
Enzyme 42 | 4,146
Ion Channel 23 | 341
GPCR 9 | 408
Kinase 9 | 634
Transcription Factor 6 | 1,400

Compartment GO Term

Apical part of cell 331 | 331
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.29593 203.1 88
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.84839 135.6 220
Folate receptor alpha FOLR1 Tchem Non-IDG -2.27944 181.4 235
Serine protease hepsin HPN Tchem Enzyme -2.46640 312.3 106
Aquaporin-1 AQP1 Tbio Non-IDG -3.06090 1040.5 321
Trichoplein keratin filament-binding protein TCHP Tbio Non-IDG -2.30520 126.7 92
Monocarboxylate transporter 1 SLC16A1 Tchem Transporter -2.42636 263.7 235
Folate transporter 1 SLC19A1 Tchem Transporter -1.98678 92.5 52
Prominin-1 PROM1 Tbio Non-IDG -3.27144 1922.5 226
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.50018 27956.4 30