Development Level

Tbio 115 | 11,445
Tdark 11 | 6,588
Tchem 7 | 1,598

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal behavior 4 | 298
abnormal retina morphology 4 | 71
decreased grip strength 3 | 116
decreased total body fat amoun... 3 | 207
abnormal embryo size 2 | 220
abnormal heart left ventricle ... 2 | 16
abnormal retinal vasculature m... 2 | 27
abnormal sleep behavior 2 | 70
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating insulin ... 2 | 76
decreased startle reflex 2 | 75
hyperactivity 2 | 148
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased bone mineral content 2 | 108
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal forebrain morphology 1 | 10
abnormal head morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
cyanosis 1 | 7
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating free fat... 1 | 31
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased circulating unsatura... 1 | 2
decreased coping response 1 | 8
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
hemorrhage 1 | 23
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased vertical activity 1 | 24
male infertility 1 | 123
mammalian phenotype 1 | 17
prenatal lethality 1 | 28
shortened PR interval 1 | 6
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 97 | 11,493
ovarian cancer 83 | 8,520
osteosarcoma 67 | 7,950
psoriasis 58 | 6,694
medulloblastoma, large-cell 54 | 6,241
intraductal papillary-mucinous carcinoma (IPMC) 52 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 52 | 3,291
atypical teratoid / rhabdoid tumor 51 | 5,112
ependymoma 48 | 4,679
glioblastoma 46 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 46 | 2,955
non-small cell lung cancer 43 | 2,890
Breast cancer 42 | 3,578
interstitial cystitis 42 | 2,312
invasive ductal carcinoma 40 | 2,951
lung cancer 40 | 4,740
group 3 medulloblastoma 38 | 4,104
lung adenocarcinoma 36 | 2,716
pancreatic cancer 35 | 2,398
Cancer 33 | 2,499
ductal carcinoma in situ 33 | 1,745
lung carcinoma 32 | 2,843
Kidney cancer 31 | 2,613
primitive neuroectodermal tumor 29 | 3,035
adult high grade glioma 27 | 3,801
malignant mesothelioma 27 | 3,232
oligodendroglioma 27 | 2,850
spina bifida 26 | 1,074
Astrocytoma, Pilocytic 25 | 3,081
pituitary cancer 25 | 1,972
subependymal giant cell astrocytoma 25 | 2,287
astrocytic glioma 24 | 2,597
breast carcinoma 22 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
cystic fibrosis 18 | 1,696
group 4 medulloblastoma 18 | 1,855
ulcerative colitis 18 | 1,819
primary pancreatic ductal adenocarcinoma 16 | 1,109
Pick disease 15 | 1,894
Autosomal recessive predisposition 13 | 1,442
Prostatic Neoplasms 13 | 495
Schizophrenia 13 | 1,160
active Crohn's disease 13 | 922
adrenocortical carcinoma 13 | 1,428
nasopharyngeal carcinoma 13 | 1,058
active ulcerative colitis 12 | 764
diabetes mellitus 12 | 1,728
esophageal adenocarcinoma 12 | 737
gastric carcinoma 12 | 807
Atopic dermatitis 11 | 952
Intellectual disability 11 | 1,016
Melanoma 11 | 711
colon cancer 11 | 1,478
Skin cancer 10 | 469
astrocytoma 10 | 1,146
pediatric high grade glioma 10 | 1,064
tuberculosis 10 | 2,010
Kidney disease 9 | 430
Liver cancer 9 | 604
acute quadriplegic myopathy 9 | 1,158
juvenile dermatomyositis 9 | 1,187
non primary Sjogren syndrome sicca 9 | 891
Bipolar Disorder 8 | 666
Breast Neoplasms 8 | 445
Inflammatory bowel disease 8 | 151
Liver Cirrhosis, Experimental 8 | 769
cutaneous lupus erythematosus 8 | 1,057
progressive supranuclear palsy 8 | 676
urothelial carcinoma 8 | 318
Down syndrome 7 | 499
Dull intelligence 7 | 645
Low intelligence 7 | 645
Mammary Neoplasms 7 | 425
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
Stomach Neoplasms 7 | 300
acute myeloid leukemia 7 | 783
dermatomyositis 7 | 966
fibroadenoma 7 | 559
medulloblastoma 7 | 720
Alzheimer's disease 6 | 658
Cerebrovascular disease 6 | 238
Diarrhea 6 | 253
Duchenne muscular dystrophy 6 | 601
Endometrial cancer 6 | 311
Endometriosis 6 | 540
Epilepsy 6 | 792
Glaucoma 6 | 239
Hypertensive disease 6 | 292
Multiple myeloma 6 | 1,332
Muscle hypotonia 6 | 571
Osteoporosis 6 | 363
Polycystic ovary syndrome 6 | 360
Rheumatoid arthritis 6 | 1,191
aldosterone-producing adenoma 6 | 665
atypical teratoid/rhabdoid tumor 6 | 357
interstitial lung disease 6 | 298
mucosa-associated lymphoid tissue lymphoma 6 | 484
primary Sjogren syndrome 6 | 735

Tissue

Digestive Tract 127 | 17,369
Female tissues 127 | 17,400
Endocrine System 126 | 18,159
Urinary Tract 126 | 16,678
Skin and soft tissues 125 | 17,230
Male tissues 124 | 17,142
Liver and Pancreas 121 | 16,750
Nervous System 121 | 16,725
Respiratory system 121 | 16,393
Blood and immune system 120 | 16,909
Cardiovascular System 114 | 15,192

Target Family

Non-IDG 115 | 12,091
Enzyme 11 | 4,145
Kinase 5 | 634
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

Apical junction complex 133 | 133
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Claudin-16 CLDN16 Tbio Non-IDG -1.98248 102.4 138
Tubulin-specific chaperone D TBCD Tbio Non-IDG -1.71996 50.5 50
Protein Shroom2 SHROOM2 Tbio Non-IDG -1.07032 11.9 112
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.08587 12.0 153
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Epithelial cell adhesion molecule EPCAM Tbio Non-IDG -3.20358 1618.6 2244
Rap guanine nucleotide exchange factor 2 RAPGEF2 Tbio Non-IDG -1.41107 29.0 79
Na(+)/H(+) exchange regulatory cofactor NHE-RF4 PDZD3 Tbio Non-IDG -0.76581 6.17 121
Claudin-1 CLDN1 Tbio Non-IDG -2.07626 126.7 593
Y-box-binding protein 3 YBX3 Tbio Transcription Factor -2.13168 143.1 204