Development Level

Tbio 88 | 10,625
Tchem 43 | 1,890
Tclin 19 | 602
Tdark 3 | 7,003

Collection

Eligible Ion Channel Proteins 3 | 117

IMPC Term

preweaning lethality, complete... 13 | 633
abnormal retina morphology 5 | 100
decreased bone mineral content 4 | 157
embryonic lethality prior to t... 4 | 187
increased circulating alkaline... 4 | 119
decreased bone mineral density 3 | 126
decreased grip strength 3 | 123
decreased lean body mass 3 | 195
increased circulating creatini... 3 | 29
increased grip strength 3 | 83
abnormal behavior 2 | 226
abnormal retinal pigmentation 2 | 61
decreased spleen weight 2 | 13
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
impaired glucose tolerance 2 | 52
increased B cell number 2 | 23
increased blood urea nitrogen ... 2 | 44
increased bone mineral density 2 | 52
increased circulating HDL chol... 2 | 63
increased circulating total pr... 2 | 20
increased total body fat amoun... 2 | 57
preweaning lethality, incomple... 2 | 260
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal cornea morphology 1 | 24
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal facial morphology 1 | 9
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal lung morphology 1 | 15
abnormal optic disc morphology 1 | 10
abnormal posture 1 | 5
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
cardiovascular system phenotyp... 1 | 35
cleft palate 1 | 6
corneal opacity 1 | 25
cyanosis 1 | 6
decreased NK T cell number 1 | 28
decreased blood urea nitrogen ... 1 | 31
decreased body weight 1 | 174
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased kidney weight 1 | 7
decreased mean corpuscular hem... 1 | 34
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased startle reflex 1 | 48
enlarged epididymis 1 | 27
female infertility 1 | 34
hypoactivity 1 | 89
immune system phenotype 1 | 17
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased NK T cell number 1 | 11
increased T cell number 1 | 15
increased body weight 1 | 42
increased circulating alanine ... 1 | 11
increased circulating amylase ... 1 | 13
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased eosinophil cell numb... 1 | 9
increased exploration in new e... 1 | 56
increased gamma-delta T cell n... 1 | 16
increased kidney weight 1 | 4
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased plasma cell number 1 | 5
increased rib number 1 | 41
limb grasping 1 | 35
narrow eye opening 1 | 15
polycystic kidney 1 | 9
straub tail 1 | 26
tremors 1 | 34
trunk curl 1 | 15

Disease

psoriasis 75 | 6,685
Cancer 66 | 2,346
ovarian cancer 66 | 8,484
osteosarcoma 64 | 7,933
lung cancer 56 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 48 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 47 | 2,956
Carcinoma 44 | 2,147
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,988
medulloblastoma, large-cell 42 | 6,234
malignant mesothelioma 40 | 3,162
non-small cell lung cancer 39 | 2,798
cystic fibrosis 37 | 1,665
glioblastoma 36 | 5,572
Breast cancer 35 | 3,094
atypical teratoid / rhabdoid tumor 35 | 4,369
interstitial cystitis 35 | 2,299
lung adenocarcinoma 35 | 2,713
pancreatic cancer 35 | 2,300
ulcerative colitis 35 | 2,087
Kidney disease 33 | 396
lung carcinoma 31 | 2,844
diabetes mellitus 28 | 1,663
invasive ductal carcinoma 25 | 2,950
Diarrhea 24 | 155
ductal carcinoma in situ 23 | 1,745
pituitary cancer 23 | 1,972
Hypertension 22 | 287
Rheumatoid Arthritis 22 | 1,160
colon cancer 22 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,795
pediatric high grade glioma 22 | 2,712
Mammary Neoplasms 21 | 410
active Crohn's disease 21 | 918
tuberculosis 21 | 1,557
Cholestasis 20 | 93
ependymoma 20 | 2,514
oligodendroglioma 20 | 2,849
pilocytic astrocytoma 20 | 3,086
primitive neuroectodermal tumor 20 | 3,031
Liver disease 19 | 219
Metabolic acidosis 19 | 49
Prostatic Neoplasms 19 | 471
esophageal adenocarcinoma 19 | 737
Inflammatory bowel disease 18 | 142
subependymal giant cell astrocytoma 18 | 2,287
Cerebrovascular disease 17 | 231
Obesity 17 | 616
cutaneous lupus erythematosus 17 | 1,056
nasopharyngeal carcinoma 17 | 1,056
Coronary artery disease 16 | 240
Heart disease 16 | 279
adrenocortical carcinoma 16 | 1,427
adult high grade glioma 16 | 2,148
primary pancreatic ductal adenocarcinoma 16 | 1,271
Endometriosis 15 | 535
astrocytic glioma 15 | 2,241
breast carcinoma 15 | 1,614
Down syndrome 14 | 548
Peripheral Neuropathy 14 | 303
Alzheimer's disease 13 | 644
Anemia 13 | 252
Pick disease 13 | 1,893
group 3 medulloblastoma 13 | 2,254
nephrosclerosis 13 | 329
posterior fossa group A ependymoma 13 | 1,511
Colorectal Neoplasms 12 | 217
Epilepsy 12 | 346
Hypokalemia 12 | 40
astrocytoma 12 | 1,493
gastric carcinoma 12 | 832
medulloblastoma 12 | 1,524
spina bifida 12 | 1,064
Barrett's esophagus 11 | 183
Hypertensive disease 11 | 193
Osteoporosis 11 | 257
active ulcerative colitis 11 | 477
chronic rhinosinusitis 11 | 512
posterior fossa group B ependymoma 11 | 1,530
urothelial carcinoma 11 | 318
Hypersensitivity reaction type II disease 10 | 235
Multiple Sclerosis 10 | 498
Pancreatitis 10 | 97
Stomach Neoplasms 10 | 282
progressive supranuclear palsy 10 | 674
Adenoma 9 | 165
Asthma 9 | 349
Atherosclerosis 9 | 275
Brain edema 9 | 26
Calcinosis 9 | 62
Edema 9 | 38
Gout 9 | 93
Hypoglycemia 9 | 81
acute quadriplegic myopathy 9 | 1,157
dermatomyositis 9 | 933
sonic hedgehog group medulloblastoma 9 | 1,482
Lung disease 8 | 132
Multiple myeloma 8 | 1,327
Polydactyly 8 | 93
gastric cancer 8 | 430

Tissue

Digestive Tract 152 | 18,473
Endocrine System 152 | 18,512
Female tissues 152 | 18,647
Nervous System 152 | 18,561
Urinary Tract 152 | 18,444
Liver and Pancreas 150 | 18,136
Skin and soft tissues 150 | 18,115
Blood and immune system 149 | 17,995
Cardiovascular System 148 | 17,958
Male tissues 147 | 17,969
Respiratory system 145 | 17,484

Target Family

Non-IDG 70 | 11,971
Transporter 48 | 473
Ion Channel 13 | 341
Enzyme 12 | 4,146
Transcription Factor 6 | 1,400
GPCR 2 | 406
Kinase 2 | 634

Compartment GO Term

Apical complex 153 | 153
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Sodium/hydrogen exchanger 4 SLC9A4 Tdark Transporter -1.25841 17.4 6
Ileal sodium/bile acid cotransporter SLC10A2 Tchem Transporter -2.60727 417.5 121
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.60207 398.9 288
H(+)/Cl(-) exchange transporter 5 CLCN5 Tbio Ion Channel -2.29453 217.9 141
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Radixin RDX Tbio Non-IDG -2.45592 216.9 310
Solute carrier family 15 member 1 SLC15A1 Tchem Transporter -2.70013 532.5 167
InaD-like protein PATJ Tbio Non-IDG -1.88739 77.1 91