Development Level

Tbio 238 | 11,445
Tchem 32 | 1,598
Tdark 20 | 6,588
Tclin 13 | 613

Collection

Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 29 | 979
embryonic lethality prior to t... 11 | 278
preweaning lethality, incomple... 9 | 499
abnormal embryo size 8 | 220
embryonic lethality prior to o... 8 | 239
abnormal retina morphology 7 | 71
embryonic growth retardation 7 | 106
abnormal behavior 6 | 298
decreased body weight 6 | 161
decreased fasted circulating g... 5 | 65
decreased total body fat amoun... 5 | 207
decreased bone mineral content 4 | 151
decreased circulating glucose ... 4 | 126
decreased grip strength 4 | 116
edema 4 | 59
hypoactivity 4 | 132
increased lean body mass 4 | 172
increased startle reflex 4 | 112
male infertility 4 | 123
abnormal bone structure 3 | 187
abnormal pericardium morpholog... 3 | 26
decreased body length 3 | 101
decreased bone mineral density 3 | 126
decreased lean body mass 3 | 135
decreased leukocyte cell numbe... 3 | 73
decreased startle reflex 3 | 75
decreased vertical activity 3 | 208
hyperactivity 3 | 148
increased blood urea nitrogen ... 3 | 48
increased body weight 3 | 25
increased bone mineral density 3 | 72
increased circulating choleste... 3 | 66
increased mean corpuscular vol... 3 | 92
increased total body fat amoun... 3 | 134
abnormal bone mineralization 2 | 38
abnormal cornea morphology 2 | 31
abnormal craniofacial morpholo... 2 | 33
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal neural tube closure 2 | 46
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
abnormal testis morphology 2 | 43
decreased circulating alanine ... 2 | 47
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased eosinophil cell numb... 2 | 24
decreased lymphocyte cell numb... 2 | 83
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating iron lev... 2 | 30
increased circulating triglyce... 2 | 42
increased grip strength 2 | 41
increased heart weight 2 | 62
increased neutrophil cell numb... 2 | 46
increased or absent threshold ... 2 | 101
persistence of hyaloid vascula... 2 | 33
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
small testis 2 | 58
thrombocytopenia 2 | 56
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal cranium morphology 1 | 36
abnormal head morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
brachydactyly 1 | 19
decreased T cell number 1 | 15
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating phosphat... 1 | 27
decreased erythrocyte cell num... 1 | 62
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
dilated heart left ventricle 1 | 11
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydrometra 1 | 53
impaired righting response 1 | 26
increased circulating bilirubi... 1 | 16
increased circulating potassiu... 1 | 29
increased fasted circulating g... 1 | 76
prenatal lethality 1 | 28
small kidney 1 | 16
small superior vagus ganglion 1 | 74
small thymus 1 | 16
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

Carcinoma 228 | 11,493
ovarian cancer 191 | 8,520
osteosarcoma 175 | 7,950
glioblastoma 150 | 5,792
medulloblastoma, large-cell 141 | 6,241
psoriasis 138 | 6,694
atypical teratoid / rhabdoid tumor 122 | 5,112
ependymoma 115 | 4,679
Cancer 113 | 2,499
lung cancer 113 | 4,740
non-small cell lung cancer 105 | 2,890
Breast cancer 100 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 97 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 96 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 92 | 2,955
group 3 medulloblastoma 89 | 4,104
adult high grade glioma 87 | 3,801
malignant mesothelioma 86 | 3,232
Astrocytoma, Pilocytic 85 | 3,081
invasive ductal carcinoma 85 | 2,951
pancreatic cancer 85 | 2,398
Kidney cancer 80 | 2,613
interstitial cystitis 78 | 2,312
lung adenocarcinoma 76 | 2,716
lung carcinoma 74 | 2,843
primitive neuroectodermal tumor 74 | 3,035
oligodendroglioma 68 | 2,850
subependymal giant cell astrocytoma 66 | 2,287
astrocytic glioma 57 | 2,597
cystic fibrosis 52 | 1,696
ductal carcinoma in situ 52 | 1,745
breast carcinoma 51 | 1,638
pituitary cancer 50 | 1,972
spina bifida 50 | 1,074
group 4 medulloblastoma 48 | 1,855
ulcerative colitis 48 | 1,819
primary pancreatic ductal adenocarcinoma 47 | 1,109
tuberculosis 47 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 45 | 1,962
Pick disease 44 | 1,894
diabetes mellitus 41 | 1,728
astrocytoma 40 | 1,146
colon cancer 40 | 1,478
adrenocortical carcinoma 39 | 1,428
dermatomyositis 38 | 966
acute quadriplegic myopathy 34 | 1,158
juvenile dermatomyositis 34 | 1,187
Liver Cirrhosis, Experimental 33 | 769
pediatric high grade glioma 33 | 1,064
esophageal adenocarcinoma 32 | 737
Melanoma 30 | 711
Autosomal recessive predisposition 29 | 1,442
Rheumatoid arthritis 29 | 1,191
Schizophrenia 27 | 1,160
Prostatic Neoplasms 25 | 495
Skin cancer 25 | 469
nasopharyngeal carcinoma 25 | 1,058
Breast Neoplasms 24 | 445
Intellectual disability 24 | 1,016
Down syndrome 23 | 499
Mammary Neoplasms 23 | 425
autosomal dominant Emery-Dreifuss muscular dystrophy 23 | 510
cutaneous lupus erythematosus 23 | 1,057
gastric carcinoma 23 | 807
Multiple myeloma 21 | 1,332
Waldenstrons macroglobulinemia 21 | 765
Liver cancer 20 | 604
aldosterone-producing adenoma 20 | 665
Duchenne muscular dystrophy 19 | 601
Kidney disease 19 | 430
Neoplasm Invasiveness 19 | 161
active Crohn's disease 18 | 922
fibroadenoma 18 | 559
medulloblastoma 18 | 720
non primary Sjogren syndrome sicca 18 | 891
pancreatic carcinoma 18 | 562
Osteoporosis 17 | 363
mucosa-associated lymphoid tissue lymphoma 17 | 484
Atopic dermatitis 16 | 952
Carcinoma, Squamous Cell 16 | 110
Neoplasm Metastasis 16 | 168
Squamous cell carcinoma 16 | 129
primary Sjogren syndrome 16 | 735
Alzheimer's disease 15 | 658
Bipolar Disorder 15 | 666
Dull intelligence 15 | 645
Low intelligence 15 | 645
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Poor school performance 15 | 645
Stomach Neoplasms 15 | 300
active ulcerative colitis 15 | 764
Multiple Sclerosis 14 | 540
Vascular disease 14 | 319
gastric cancer 14 | 459
posterior fossa group A ependymoma 14 | 468
Endometriosis 13 | 540
Obesity 13 | 678
Short stature 13 | 531
acute myeloid leukemia 13 | 783

Tissue

Digestive Tract 297 | 17,369
Skin and soft tissues 297 | 17,230
Blood and immune system 296 | 16,909
Endocrine System 296 | 18,159
Female tissues 296 | 17,400
Male tissues 296 | 17,142
Nervous System 293 | 16,725
Urinary Tract 293 | 16,678
Liver and Pancreas 292 | 16,750
Respiratory system 291 | 16,393
Cardiovascular System 280 | 15,192

Target Family

Non-IDG 230 | 12,091
Enzyme 37 | 4,145
Kinase 28 | 634
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473

Compartment GO Term

Anchoring junction 303 | 303
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Tubulin-specific chaperone D TBCD Tbio Non-IDG -1.71996 50.5 50
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 ALKBH6 Tdark Enzyme 0.38 0.31 58
Protein Shroom2 SHROOM2 Tbio Non-IDG -1.07032 11.9 112
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.08587 12.0 153
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Small cell adhesion glycoprotein SMAGP Tdark Non-IDG -0.06695 1.95 82