Development Level

Tbio 5 | 11,445

IMPC Phenotype

impaired glucose tolerance 1 | 75

Disease

Breast cancer 5 | 3,578
osteosarcoma 5 | 7,950
ulcerative colitis 5 | 1,819
Carcinoma 4 | 11,493
Duchenne muscular dystrophy 4 | 601
atypical teratoid / rhabdoid tumor 4 | 5,112
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
ovarian cancer 4 | 8,520
pancreatic cancer 4 | 2,398
Astrocytoma, Pilocytic 3 | 3,081
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
primary pancreatic ductal adenocarcinoma 3 | 1,109
Atopic dermatitis 2 | 952
Biliary cirrhosis 2 | 45
Breast Neoplasms 2 | 445
Cancer 2 | 2,499
Contracture 2 | 96
Contracture of joint 2 | 93
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Hepatitis B 2 | 108
Hepatitis C 2 | 94
Hepatolenticular Degeneration 2 | 24
Liver Cirrhosis, Biliary 2 | 33
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Polycystic ovary syndrome 2 | 360
Skin cancer 2 | 469
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
gastric carcinoma 2 | 807
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
primary Sjogren syndrome 2 | 735
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
urothelial carcinoma 2 | 318
Abnormality of the fingernails 1 | 51
Aortic aneurysm 1 | 38
Aplasia Cutis Congenita 1 | 14
Ascending aortic dissection 1 | 13
Atrophic condition of skin 1 | 25
Atrophic scar 1 | 18
Cell Transformation, Neoplastic 1 | 97
Congenital localized absence of skin 1 | 6
Congenital scar 1 | 13
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Corneal Scar 1 | 7
Corneal erosion 1 | 16
Cutis Laxa, Autosomal Recessive, Type 1A 1 | 3
Cutis Laxa, Autosomal Recessive, Type I 1 | 3
Cutis marmorata 1 | 32
Cystic medial necrosis of aorta 1 | 13
Defective enamel matrix 1 | 35
Delayed Puberty 1 | 97
Dental Enamel Hypoplasia 1 | 43
Dysplasia of tooth enamel 1 | 35
Dyspnea on exertion 1 | 24
Dyspnea, Paroxysmal 1 | 13
Ectropion 1 | 38
Epidermolysis bullosa 1 | 21
Esophageal Stenosis 1 | 15
Fibroma 1 | 18
Fragile skin 1 | 18
Gaucher disease type 3 1 | 67
Hyperkyphosis 1 | 111
Hypertension, Pulmonary 1 | 37
Impaired left ventricular function 1 | 16
Increased risk of pancreatic cancer 1 | 9
Kindler syndrome 1 | 11
Kyphosis deformity of spine 1 | 114
Left-Sided Heart Failure 1 | 16
Loeys-Dietz Aortic Aneurysm Syndrome 1 | 13
Malignant Squamous Cell Neoplasm 1 | 17
Malignant neoplasm of pancreas 1 | 9
Malignant tumor of colon 1 | 19
Milium Cyst 1 | 16
Neoplastic Cell Transformation 1 | 89
Neurotic excoriation 1 | 2
Oral Submucous Fibrosis 1 | 20
Oral mucosal blistering 1 | 10
Peliosis Hepatis 1 | 4
Rotting teeth 1 | 73
Scarring alopecia of scalp 1 | 13
Skin Erosion 1 | 12
Thin dental enamel 1 | 35
Transitional cell carcinoma of bladder 1 | 17
hypopigmented skin patch 1 | 59

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 3 | 12,091
Enzyme 2 | 4,145

Compartment GO Term

Anchoring collagen complex 5 | 5
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein-lysine 6-oxidase LOX Tbio Enzyme -3.36257 2227.1 513
Collagen alpha-1(VII) chain COL7A1 Tbio Non-IDG -2.58130 371.7 95
Lysyl oxidase homolog 2 LOXL2 Tbio Enzyme -2.24186 173.0 274
Collagen alpha-1(XIV) chain COL14A1 Tbio Non-IDG -2.16307 130.6 64
Collagen alpha-1(XII) chain COL12A1 Tbio Non-IDG -1.36571 21.4 38