Development Level

Tbio 108 | 10,625
Tdark 22 | 7,003
Tchem 18 | 1,890
Tclin 4 | 602

IMPC Term

increased exploration in new e... 3 | 56
decreased body weight 2 | 174
decreased circulating insulin ... 2 | 75
decreased eosinophil cell numb... 2 | 41
female infertility 2 | 34
increased blood urea nitrogen ... 2 | 44
increased fasted circulating g... 2 | 68
preweaning lethality, incomple... 2 | 260
abnormal QRS complex 1 | 25
abnormal anxiety-related respo... 1 | 1
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal social/conspecific in... 1 | 3
abnormal spleen morphology 1 | 36
abnormal vocalization 1 | 21
convulsive seizures 1 | 11
corneal opacity 1 | 25
decreased basophil cell number 1 | 11
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating amylase ... 1 | 24
decreased circulating calcium ... 1 | 33
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged adrenal glands 1 | 3
enlarged heart 1 | 111
enlarged heart atrium 1 | 2
enlarged kidney 1 | 7
enlarged uterus 1 | 3
hydrometra 1 | 13
hypoactivity 1 | 89
increased body length 1 | 20
increased circulating chloride... 1 | 43
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
irregularly shaped pupil 1 | 7
male infertility 1 | 62
polycystic kidney 1 | 9
preweaning lethality, complete... 1 | 633
small adrenal glands 1 | 15
small kidney 1 | 10

Disease

psoriasis 74 | 6,685
osteosarcoma 62 | 7,933
ovarian cancer 56 | 8,484
glioblastoma 51 | 5,572
medulloblastoma, large-cell 48 | 6,234
lung adenocarcinoma 47 | 2,713
lung carcinoma 47 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,289
non-small cell lung cancer 39 | 2,798
Cancer 38 | 2,346
atypical teratoid / rhabdoid tumor 38 | 4,369
pilocytic astrocytoma 38 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,956
lung cancer 36 | 4,466
malignant mesothelioma 34 | 3,162
cystic fibrosis 31 | 1,665
invasive ductal carcinoma 31 | 2,950
oligodendroglioma 31 | 2,849
pancreatic cancer 31 | 2,300
pediatric high grade glioma 31 | 2,712
interstitial cystitis 30 | 2,299
ductal carcinoma in situ 28 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,988
primitive neuroectodermal tumor 28 | 3,031
Breast cancer 26 | 3,094
pituitary cancer 26 | 1,972
breast carcinoma 23 | 1,614
tuberculosis 23 | 1,557
ulcerative colitis 23 | 2,087
adult high grade glioma 21 | 2,148
ependymoma 19 | 2,514
group 4 medulloblastoma 19 | 1,875
subependymal giant cell astrocytoma 19 | 2,287
active Crohn's disease 18 | 918
cutaneous lupus erythematosus 18 | 1,056
astrocytic glioma 17 | 2,241
primary pancreatic ductal adenocarcinoma 17 | 1,271
group 3 medulloblastoma 16 | 2,254
Carcinoma 15 | 2,147
astrocytoma 15 | 1,493
Atopic dermatitis 14 | 944
colon cancer 14 | 1,475
diabetes mellitus 14 | 1,663
esophageal adenocarcinoma 14 | 737
posterior fossa group A ependymoma 14 | 1,511
posterior fossa group B ependymoma 14 | 1,530
nasopharyngeal carcinoma 13 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
Pick disease 11 | 1,893
active ulcerative colitis 11 | 477
adrenocortical carcinoma 11 | 1,427
Obesity 10 | 616
Rheumatoid Arthritis 10 | 1,160
atypical teratoid/rhabdoid tumor 10 | 1,095
gastric carcinoma 10 | 832
medulloblastoma 10 | 1,524
non-small cell lung carcinoma 10 | 413
sonic hedgehog group medulloblastoma 10 | 1,482
spina bifida 10 | 1,064
Duchenne muscular dystrophy 9 | 602
juvenile dermatomyositis 9 | 1,189
Alzheimer's disease 8 | 644
Liver disease 8 | 219
Multiple Sclerosis 8 | 498
Prostatic Neoplasms 8 | 471
mucosa-associated lymphoid tissue lymphoma 8 | 480
primary Sjogren syndrome 8 | 789
Anemia 7 | 252
Atherosclerosis 7 | 275
Autistic Disorder 7 | 320
Down syndrome 7 | 548
Hypertension 7 | 287
Schizophrenia 7 | 501
Vascular disease 7 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
dermatomyositis 7 | 933
fibroadenoma 7 | 557
nephrosclerosis 7 | 329
Endometriosis 6 | 535
Hepatitis C 6 | 90
Kidney disease 6 | 396
Acquired metabolic disease 5 | 267
Cholangitis 5 | 20
Hydrolethalus syndrome 5 | 128
Metabolic syndrome X 5 | 155
Proteinuria 5 | 63
Stomach Neoplasms 5 | 282
Toxic encephalopathy 5 | 131
aldosterone-producing adenoma 5 | 664
head and neck cancer 5 | 270
head and neck cancer and chronic obstructive pulmonary disease 5 | 237
interstitial lung disease 5 | 291
urothelial carcinoma 5 | 318
Attention deficit hyperactivity disorder 4 | 156
Cognitive disorder 4 | 44
Juvenile arthritis 4 | 124
Multiple myeloma 4 | 1,327
acute quadriplegic myopathy 4 | 1,157
chronic lymphosyte leukemia 4 | 232
periodontitis 4 | 269

Tissue

Digestive Tract 147 | 18,473
Female tissues 147 | 18,647
Nervous System 147 | 18,561
Endocrine System 146 | 18,512
Male tissues 145 | 17,969
Liver and Pancreas 144 | 18,136
Urinary Tract 144 | 18,444
Blood and immune system 143 | 17,995
Skin and soft tissues 143 | 18,115
Cardiovascular System 138 | 17,958
Respiratory system 136 | 17,484

Target Family

Non-IDG 111 | 11,971
Enzyme 40 | 4,146
Kinase 1 | 634

Compartment GO Term

Anchored component of membrane 152 | 152
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Teratocarcinoma-derived growth factor 1 TDGF1 Tbio Non-IDG 156.3 371
Xaa-Pro aminopeptidase 2 XPNPEP2 Tchem Enzyme -1.55651 32.2 97
Contactin-6 CNTN6 Tbio Non-IDG -2.02527 101.3 65
Otoancorin OTOA Tdark Non-IDG -1.29628 19.3 48
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.51621 344.5 145
Ecto-ADP-ribosyltransferase 4 ART4 Tbio Enzyme -1.42325 26.5 108
Ly6/PLAUR domain-containing protein 6B LYPD6B Tdark Non-IDG -0.34756 2.68 18
CD59 glycoprotein CD59 Tbio Non-IDG -3.23780 1768.6 739
Glypican-1 GPC1 Tbio Non-IDG -2.34418 224.6 160
Ciliary neurotrophic factor receptor subunit alpha CNTFR Tbio Non-IDG -1.62134 35.4 184