Development Level

Tbio 38 | 11,445
Tdark 14 | 6,588
Tchem 7 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
decreased vertical activity 2 | 208
male infertility 2 | 123
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal skin morphology 1 | 50
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased heart left ventricle... 1 | 28
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hemorrhage 1 | 23
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating aspartat... 1 | 15
increased exploration in new e... 1 | 8
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2
small testis 1 | 58
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

Carcinoma 42 | 11,493
osteosarcoma 33 | 7,950
ovarian cancer 31 | 8,520
medulloblastoma, large-cell 24 | 6,241
lung cancer 21 | 4,740
ependymoma 18 | 4,679
group 3 medulloblastoma 18 | 4,104
psoriasis 18 | 6,694
Cancer 17 | 2,499
glioblastoma 16 | 5,792
atypical teratoid / rhabdoid tumor 15 | 5,112
adult high grade glioma 14 | 3,801
malignant mesothelioma 14 | 3,232
Kidney cancer 13 | 2,613
Neurodegenerative disease 12 | 414
astrocytic glioma 11 | 2,597
lung carcinoma 11 | 2,843
oligodendroglioma 11 | 2,850
primitive neuroectodermal tumor 11 | 3,035
Breast cancer 10 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
non-small cell lung cancer 9 | 2,890
Astrocytoma, Pilocytic 8 | 3,081
group 4 medulloblastoma 8 | 1,855
interstitial cystitis 8 | 2,312
invasive ductal carcinoma 8 | 2,951
lung adenocarcinoma 8 | 2,716
pituitary cancer 8 | 1,972
subependymal giant cell astrocytoma 8 | 2,287
Depressive disorder 7 | 409
Dysarthria 7 | 192
Pick disease 7 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Dystonia 6 | 164
Multiple myeloma 6 | 1,332
Nerve Degeneration 6 | 121
Waldenstrons macroglobulinemia 6 | 765
diabetes mellitus 6 | 1,728
tuberculosis 6 | 2,010
Amyotrophic lateral sclerosis 5 | 451
Deglutition Disorders 5 | 132
Dementia 5 | 175
Personality change 5 | 23
acute quadriplegic myopathy 5 | 1,158
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
dermatomyositis 5 | 966
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
ulcerative colitis 5 | 1,819
Adult onset 4 | 82
Alzheimer's disease 4 | 658
Anxiety 4 | 136
Anxiety disease 4 | 113
Cardiomyopathy 4 | 116
Dyslexia 4 | 43
Dystonic disease 4 | 106
Frontotemporal dementia 4 | 51
Huntington's disease 4 | 76
Muscle Cramp 4 | 55
Neurodegenerative Disorders 4 | 79
Parkinson's disease 4 | 392
Progressive disorder 4 | 142
Social disinhibition 4 | 14
Toxic encephalopathy 4 | 141
breast carcinoma 4 | 1,638
pancreatic cancer 4 | 2,398
Aggressive behavior 3 | 75
Aggressive reaction 3 | 75
Babinski Reflex 3 | 100
Bradykinesia 3 | 34
Cerebral atrophy 3 | 178
Congestive heart failure 3 | 113
Cortical white matter abnormalities seen on MRI 3 | 18
Creatine phosphokinase serum increased 3 | 110
Decreased tendon reflex 3 | 122
Elevated creatine kinase 3 | 110
Fatigue 3 | 182
Generalized muscle weakness 3 | 57
Heart failure 3 | 162
Highly variable clinical phenotype 3 | 150
Highly variable phenotype and severity 3 | 150
Highly variable phenotype, even within families 3 | 150
Hyperreflexia 3 | 209
Leukoaraiosis 3 | 18
Liver Cirrhosis, Experimental 3 | 769
Loss of speech 3 | 16
Melanoma 3 | 711
Mood swings 3 | 77
Muscle Spasticity 3 | 195
Neurogenic Muscular Atrophy 3 | 139
Neurogenic muscle atrophy, especially in the lower limbs 3 | 139
Phenotypic variability 3 | 150
Physical aggression 3 | 76
Respiratory Failure 3 | 104
Skeletal muscle atrophy 3 | 139
Stereotyped Behavior 3 | 37
Stereotypic Movement Disorder 3 | 42
active ulcerative colitis 3 | 764
muscle degeneration 3 | 139
progressive supranuclear palsy 3 | 676

Tissue

Endocrine System 61 | 18,159
Female tissues 61 | 17,400
Blood and immune system 60 | 16,909
Digestive Tract 60 | 17,369
Male tissues 60 | 17,142
Skin and soft tissues 60 | 17,230
Urinary Tract 60 | 16,678
Liver and Pancreas 59 | 16,750
Respiratory system 59 | 16,393
Cardiovascular System 57 | 15,192
Nervous System 57 | 16,725

Target Family

Non-IDG 34 | 12,091
Enzyme 14 | 4,145
Transcription Factor 5 | 1,400
Kinase 4 | 634
Epigenetic 3 | 242
TF/Epigenetic 1 | 38

Compartment GO Term

Aggresome 61 | 61
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
E3 ubiquitin-protein ligase TRIM50 TRIM50 Tdark Enzyme -0.46630 3.11 109
BAG family molecular chaperone regulator 3 BAG3 Tbio Non-IDG -2.26339 208.9 289
Tripartite motif-containing protein 66 TRIM66 Tdark Epigenetic -0.11394 2.15 17
Putative uncharacterized protein C19orf81 C19orf81 Tdark Non-IDG 0.00000 3
E3 ubiquitin-protein ligase TRIM37 TRIM37 Tbio Enzyme -3.25892 1754.8 177
RING finger protein 32 RNF32 Tdark Non-IDG -0.50515 2.10 62
5'-3' exoribonuclease 2 XRN2 Tbio Enzyme -1.52792 31.8 121
Zinc finger and BTB domain-containing protein 14 ZBTB14 Tbio Transcription Factor -1.36289 24.1 47
Elongation factor 2 EEF2 Tchem Non-IDG -2.95619 938.4 363