Development Level

Tbio 14 | 11,445
Tchem 3 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal eye morphology 2 | 68
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye pigmentation 1 | 3
abnormal eye size 1 | 7
abnormal eyelid aperture 1 | 2
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal neural tube morpholog... 1 | 12
abnormal tooth morphology 1 | 24
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
eyelids fail to open 1 | 3
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

Carcinoma 14 | 11,493
osteosarcoma 11 | 7,950
ovarian cancer 11 | 8,520
psoriasis 10 | 6,694
Kidney cancer 8 | 2,613
glioblastoma 8 | 5,792
lung cancer 7 | 4,740
atypical teratoid / rhabdoid tumor 6 | 5,112
lung adenocarcinoma 6 | 2,716
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
non-small cell lung cancer 6 | 2,890
Breast cancer 5 | 3,578
group 3 medulloblastoma 5 | 4,104
invasive ductal carcinoma 5 | 2,951
oligodendroglioma 5 | 2,850
Astrocytoma, Pilocytic 4 | 3,081
Cancer 4 | 2,499
adult high grade glioma 4 | 3,801
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,855
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
non primary Sjogren syndrome sicca 3 | 891
pancreatic cancer 3 | 2,398
Cough 2 | 23
Dysuria 2 | 26
Epilepsy 2 | 792
Epilepsy characterized by intractable complex partial seizures 2 | 28
Itching of skin 2 | 18
Lennox-Gastaut syndrome 2 | 34
Life-Threatening Ventricular Tachycardia 2 | 15
Local anesthesia 2 | 40
Localization-related epilepsy 2 | 13
Minor Skin Wound Pain 2 | 12
Motor cortex epilepsy 2 | 10
Mouth Irritation 2 | 12
Multiple myeloma 2 | 1,332
Partial seizure 2 | 15
Prevent Minor Bacterial Skin Infection 2 | 10
Skin irritation 2 | 12
Sore throat symptom 2 | 12
Spinocerebellar ataxia type 7 2 | 13
Suppression of the Gag Reflex 2 | 12
Tinea Infections 2 | 10
Tinea corporis 2 | 25
Tinea pedis 2 | 29
Tonic-clonic epilepsy 2 | 47
Urinary Tract Irritation 2 | 24
Ventricular arrhythmia 2 | 27
Waldenstrons macroglobulinemia 2 | 765
adrenocortical adenoma 2 | 131
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Agenesis of teeth 1 | 21
Cholestasis, Extrahepatic 1 | 25
Colorectal cancer 1 | 25
Congenital diaphragmatic hernia 1 | 67
Congenital sensorineural hearing loss 1 | 12
Dacryoadenitis 1 | 10
Dental abnormalities 1 | 60
Epidermolysis bullosa 1 | 21
Episodic flaccid weakness 1 | 4
Episodic hypokalemia 1 | 4
Exercise-induced muscle fatigue 1 | 5
Hamman-Rich syndrome 1 | 34
Hyperkalemia 1 | 17
Hyperkalemic periodic paralysis 1 | 9
Hypokalemia 1 | 52
Hypokalemic periodic paralysis 1 | 11
Hypokalemic periodic paralysis type 1 1 | 3
Increased intramyocellular lipid droplets 1 | 13
Mildly increased creatine kinase 1 | 20
Mitral regurgitation, mild 1 | 32
Mumps 1 | 10
Muscle Cramp 1 | 55
Myasthenias 1 | 8
Ollier disease 1 | 18
Periodic hypokalemic paresis 1 | 7
Reduced number of teeth 1 | 21
Short thumb terminal phalanx 1 | 5
Skeletal muscle hypertrophy 1 | 16
Staphyloenterotoxemia 1 | 18
Thyroid cancer 1 | 36
Tooth Abnormalities 1 | 69
Trigeminal Neuralgia 1 | 24

Tissue

Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Skin and soft tissues 20 | 17,230
Blood and immune system 19 | 16,909
Cardiovascular System 19 | 15,192
Urinary Tract 19 | 16,678
Nervous System 18 | 16,725
Respiratory system 18 | 16,393

Target Family

Non-IDG 11 | 12,091
Epigenetic 3 | 242
Enzyme 2 | 4,145
Ion Channel 2 | 344
Transcription Factor 2 | 1,400
Kinase 1 | 634

Compartment GO Term

Ada2/Gcn5/Ada3 transcription a... 21 | 21
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired mesoderm homeobox protein 2 PRRX2 Tbio Transcription Factor -0.80932 7.56 127
Pre-mRNA-splicing factor 18 PRPF18 Tbio Non-IDG -1.36183 19.8 84
YEATS domain-containing protein 2 YEATS2 Tbio Non-IDG -0.51547 3.19 61
Acidic repeat-containing protein GCNA Tbio Non-IDG -1.34261 20.4 75
Dedicator of cytokinesis protein 11 DOCK11 Tdark Non-IDG -1.84321 58.6 35
Transcriptional adapter 2-alpha TADA2A Tbio Transcription Factor -0.90883 7.79 0
Sodium channel protein type 4 subunit alpha SCN4A Tclin Ion Channel -2.57811 366.4 57
Histone acetyltransferase KAT2A KAT2A Tbio Epigenetic -2.46487 271.9 262
Cysteine-rich protein 2-binding protein KAT14 Tbio Non-IDG -0.90082 7.81 111
Protein Dr1 DR1 Tbio Non-IDG -2.51135 313.8 146