Development Level

Tbio 41 | 11,445
Tchem 14 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal embryo size 3 | 220
abnormal bone structure 2 | 187
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased erythrocyte cell num... 1 | 62
decreased startle reflex 1 | 75
enlarged heart 1 | 210
enlarged testis 1 | 6
increased circulating alkaline... 1 | 122
increased circulating total pr... 1 | 28
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 39 | 11,493
Cancer 34 | 2,499
ovarian cancer 31 | 8,520
osteosarcoma 24 | 7,950
psoriasis 24 | 6,694
lung cancer 20 | 4,740
atypical teratoid / rhabdoid tumor 19 | 5,112
medulloblastoma, large-cell 18 | 6,241
glioblastoma 17 | 5,792
diabetes mellitus 16 | 1,728
ependymoma 16 | 4,679
Astrocytoma, Pilocytic 15 | 3,081
Breast cancer 14 | 3,578
adult high grade glioma 14 | 3,801
invasive ductal carcinoma 14 | 2,951
group 3 medulloblastoma 13 | 4,104
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
cystic fibrosis 11 | 1,696
lung adenocarcinoma 11 | 2,716
non-small cell lung cancer 11 | 2,890
Kidney cancer 10 | 2,613
group 4 medulloblastoma 10 | 1,855
oligodendroglioma 10 | 2,850
breast carcinoma 9 | 1,638
ductal carcinoma in situ 9 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
ulcerative colitis 9 | 1,819
Fibrodysplasia ossificans progressiva 8 | 17
Hypertensive disease 8 | 292
Kidney disease 8 | 430
Liver Cirrhosis, Experimental 8 | 769
Osteoporosis 8 | 363
Pulmonary Fibrosis 8 | 106
Ureteral obstruction 8 | 33
colon cancer 8 | 1,478
Acquired scoliosis 7 | 281
Autosomal recessive predisposition 7 | 1,442
Cleft Palate 7 | 271
Curvature of spine 7 | 282
Myopathy 7 | 185
Polycystic ovary syndrome 7 | 360
astrocytic glioma 7 | 2,597
pituitary cancer 7 | 1,972
primitive neuroectodermal tumor 7 | 3,035
Breast Neoplasms 6 | 445
Colorectal Neoplasms 6 | 243
Craniofacial Abnormalities 6 | 151
Heart disease 6 | 306
Holoprosencephaly 6 | 56
Hypertension 6 | 396
Increase in blood pressure 6 | 119
Infertility 6 | 188
Liver Cirrhosis 6 | 181
Liver disease 6 | 237
Mammary Neoplasms 6 | 425
Osteoarthritis 6 | 184
Schizophrenia 6 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
pancreatic cancer 6 | 2,398
Amenorrhea 5 | 58
Anemia 5 | 365
Ankylosis 5 | 28
Brachydactyly 5 | 156
Coronary artery disease 5 | 268
Craniosynostosis 5 | 74
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Diabetes Mellitus, Type 2 5 | 142
Failure to gain weight 5 | 365
Hereditary hemorrhagic telangiectasia 5 | 13
Hyperglycemia 5 | 137
Orbital separation excessive 5 | 244
Pediatric failure to thrive 5 | 365
Pick disease 5 | 1,894
Pre-Eclampsia 5 | 68
Premature ovarian failure 5 | 65
Prostatic Neoplasms 5 | 495
Short stature 5 | 531
Vascular disease 5 | 319
acute quadriplegic myopathy 5 | 1,158
astrocytoma 5 | 1,146
nasopharyngeal carcinoma 5 | 1,058
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Abortion, Spontaneous 4 | 109
Adenoma 4 | 167
Byzanthine arch palate 4 | 194
Carcinoma, Hepatocellular 4 | 228
Decreased joint mobility 4 | 53
Endometriosis 4 | 540
Liver carcinoma 4 | 240
Lung disease 4 | 142
Seizures 4 | 596
Spontaneous abortion 4 | 113
Stomach Neoplasms 4 | 300
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
pediatric high grade glioma 4 | 1,064

Tissue

Endocrine System 53 | 18,159
Digestive Tract 52 | 17,369
Female tissues 51 | 17,400
Liver and Pancreas 49 | 16,750
Nervous System 49 | 16,725
Skin and soft tissues 48 | 17,230
Blood and immune system 47 | 16,909
Male tissues 47 | 17,142
Respiratory system 47 | 16,393
Urinary Tract 46 | 16,678
Cardiovascular System 44 | 15,192

Target Family

Non-IDG 31 | 12,091
Transcription Factor 14 | 1,400
Kinase 10 | 634
Enzyme 2 | 4,145
GPCR 1 | 408

Compartment GO Term

Activin complex 58 | 58
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Putative teratocarcinoma-derived growth factor 3 TDGF1P3 Tdark Non-IDG -1.99746 160.4 0
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.07569 106.7 450
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Bone morphogenetic protein receptor type-1B BMPR1B Tchem Kinase -2.00303 86.8 498
Growth/differentiation factor 8 MSTN Tbio Non-IDG -3.08307 1338.8 568
Putative homeobox protein NANOGP8 NANOGP8 Tbio Non-IDG -2.94914 1130.5 0
Activin receptor type-1B ACVR1B Tchem Kinase -2.00550 91.2 418