Development Level

Tbio 32 | 11,445
Tchem 10 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal embryo size 3 | 220
abnormal bone structure 2 | 187
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased erythrocyte cell num... 1 | 62
decreased startle reflex 1 | 75
enlarged heart 1 | 210
enlarged testis 1 | 6
increased circulating alkaline... 1 | 122
increased circulating total pr... 1 | 28
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 31 | 11,493
Cancer 27 | 2,499
ovarian cancer 22 | 8,520
osteosarcoma 18 | 7,950
lung cancer 17 | 4,740
psoriasis 16 | 6,694
diabetes mellitus 13 | 1,728
atypical teratoid / rhabdoid tumor 12 | 5,112
interstitial cystitis 11 | 2,312
invasive ductal carcinoma 11 | 2,951
medulloblastoma, large-cell 11 | 6,241
Astrocytoma, Pilocytic 10 | 3,081
Breast cancer 10 | 3,578
ependymoma 10 | 4,679
glioblastoma 10 | 5,792
malignant mesothelioma 10 | 3,232
non-small cell lung cancer 10 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
lung adenocarcinoma 9 | 2,716
Kidney cancer 8 | 2,613
adult high grade glioma 8 | 3,801
breast carcinoma 8 | 1,638
group 3 medulloblastoma 8 | 4,104
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
oligodendroglioma 8 | 2,850
ulcerative colitis 8 | 1,819
Liver Cirrhosis, Experimental 7 | 769
cystic fibrosis 7 | 1,696
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung carcinoma 7 | 2,843
Kidney disease 6 | 430
Myopathy 6 | 185
Osteoarthritis 6 | 184
Osteoporosis 6 | 363
Pre-Eclampsia 6 | 68
colon cancer 6 | 1,478
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
Ankylosis 5 | 28
Autosomal recessive predisposition 5 | 1,442
Breast Neoplasms 5 | 445
Heart disease 5 | 306
Hypertension 5 | 396
Hypertensive disease 5 | 292
Liver disease 5 | 237
Mammary Neoplasms 5 | 425
Pulmonary Fibrosis 5 | 106
Vascular disease 5 | 319
astrocytic glioma 5 | 2,597
nasopharyngeal carcinoma 5 | 1,058
Acquired scoliosis 4 | 281
Anemia 4 | 365
Brachydactyly 4 | 156
Cleft Lip 4 | 141
Cleft Palate 4 | 271
Cognitive delay 4 | 608
Curvature of spine 4 | 282
Failure to gain weight 4 | 365
Fibrodysplasia ossificans progressiva 4 | 17
Global developmental delay 4 | 608
Holoprosencephaly 4 | 56
Hyperglycemia 4 | 137
Increase in blood pressure 4 | 119
Liver Cirrhosis 4 | 181
Liver Failure, Acute 4 | 29
Mental and motor retardation 4 | 608
Obesity 4 | 678
Orbital separation excessive 4 | 244
Pediatric failure to thrive 4 | 365
Polycystic ovary syndrome 4 | 360
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
Seizures 4 | 596
Short stature 4 | 531
Stomach Neoplasms 4 | 300
Ureteral obstruction 4 | 33
acute quadriplegic myopathy 4 | 1,158
pancreatic cancer 4 | 2,398
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Atopic dermatitis 3 | 952
Coronary artery disease 3 | 268
Craniosynostosis 3 | 74
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Down syndrome 3 | 499
Epilepsy 3 | 792
Lung disease 3 | 142
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Reperfusion Injury 3 | 86
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
cutaneous lupus erythematosus 3 | 1,057
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
head and neck cancer 3 | 271

Tissue

Digestive Tract 41 | 17,369
Endocrine System 39 | 18,159
Female tissues 39 | 17,400
Blood and immune system 37 | 16,909
Liver and Pancreas 37 | 16,750
Nervous System 37 | 16,725
Respiratory system 37 | 16,393
Skin and soft tissues 37 | 17,230
Male tissues 36 | 17,142
Urinary Tract 36 | 16,678
Cardiovascular System 33 | 15,192

Target Family

Non-IDG 25 | 12,091
Transcription Factor 10 | 1,400
Kinase 7 | 634
Enzyme 2 | 4,145

Compartment GO Term

Activin A complex 44 | 44
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
Putative teratocarcinoma-derived growth factor 3 TDGF1P3 Tdark Non-IDG -1.99746 160.4 0
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Putative homeobox protein NANOGP8 NANOGP8 Tbio Non-IDG -2.94914 1130.5 0
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Growth/differentiation factor 8 MSTN Tbio Non-IDG -3.08307 1338.8 568
Activin receptor type-1B ACVR1B Tchem Kinase -2.00550 91.2 418
Actin, alpha skeletal muscle ACTA1 Tbio Non-IDG -2.75790 541.5 749
Fibroblast growth factor 13 FGF13 Tbio Non-IDG -2.94674 831.9 368