Development Level

Tbio 129 | 11,445
Tdark 54 | 6,588
Tchem 19 | 1,598
Tclin 6 | 613

Collection

GPCR: IDG Consortium (Targets) 3 | 126
Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Target... 3 | 125

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 12 | 499
abnormal behavior 8 | 298
decreased body weight 6 | 161
decreased bone mineral content 6 | 151
enlarged heart 6 | 210
increased lean body mass 6 | 172
abnormal behavioral response t... 5 | 66
decreased vertical activity 5 | 208
embryonic lethality prior to o... 5 | 239
improved glucose tolerance 5 | 79
abnormal bone structure 4 | 187
abnormal sleep behavior 4 | 70
decreased circulating LDL chol... 4 | 38
decreased lean body mass 4 | 135
decreased total body fat amoun... 4 | 207
hyperactivity 4 | 148
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased caudal vertebrae num... 3 | 53
decreased circulating HDL chol... 3 | 68
decreased circulating alanine ... 3 | 47
decreased circulating choleste... 3 | 93
decreased circulating glucose ... 3 | 126
decreased grip strength 3 | 116
decreased heart left ventricle... 3 | 28
edema 3 | 59
embryonic lethality prior to t... 3 | 278
increased circulating alkaline... 3 | 122
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
short tibia 3 | 97
thin ventricular wall 3 | 24
abnormal coat appearance 2 | 31
abnormal eye morphology 2 | 68
abnormal testis morphology 2 | 43
cardiovascular system phenotyp... 2 | 36
decreased body length 2 | 101
decreased circulating aspartat... 2 | 34
decreased mean corpuscular vol... 2 | 79
hemorrhage 2 | 23
hydrometra 2 | 53
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased red blood cell distr... 2 | 34
limb grasping 2 | 41
prenatal lethality prior to he... 2 | 87
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
small testis 2 | 58
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal joint morphology 1 | 23
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal vertebrae morphology 1 | 18
absent pinna reflex 1 | 23
brachydactyly 1 | 19
convulsive seizures 1 | 13
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased body weight 1 | 25
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
male infertility 1 | 123
microphthalmia 1 | 26
pallor 1 | 34
shortened RR interval 1 | 17
small spleen 1 | 19
small superior vagus ganglion 1 | 74

Disease

Carcinoma 137 | 11,493
ovarian cancer 108 | 8,520
osteosarcoma 103 | 7,950
glioblastoma 89 | 5,792
medulloblastoma, large-cell 84 | 6,241
psoriasis 79 | 6,694
atypical teratoid / rhabdoid tumor 78 | 5,112
ependymoma 74 | 4,679
lung cancer 70 | 4,740
adult high grade glioma 58 | 3,801
Astrocytoma, Pilocytic 52 | 3,081
malignant mesothelioma 51 | 3,232
Breast cancer 49 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 48 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 48 | 3,291
primitive neuroectodermal tumor 47 | 3,035
group 3 medulloblastoma 45 | 4,104
non-small cell lung cancer 43 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 42 | 2,989
Kidney cancer 41 | 2,613
pancreatic cancer 40 | 2,398
invasive ductal carcinoma 39 | 2,951
lung adenocarcinoma 39 | 2,716
lung carcinoma 39 | 2,843
astrocytic glioma 38 | 2,597
oligodendroglioma 36 | 2,850
subependymal giant cell astrocytoma 32 | 2,287
group 4 medulloblastoma 30 | 1,855
Cancer 29 | 2,499
Pick disease 29 | 1,894
cystic fibrosis 28 | 1,696
tuberculosis 28 | 2,010
colon cancer 26 | 1,478
pituitary cancer 26 | 1,972
ulcerative colitis 26 | 1,819
adrenocortical carcinoma 25 | 1,428
interstitial cystitis 25 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
primary pancreatic ductal adenocarcinoma 23 | 1,109
ductal carcinoma in situ 22 | 1,745
spina bifida 22 | 1,074
Liver Cirrhosis, Experimental 20 | 769
diabetes mellitus 20 | 1,728
juvenile dermatomyositis 20 | 1,187
breast carcinoma 19 | 1,638
gastric carcinoma 19 | 807
acute quadriplegic myopathy 17 | 1,158
Autosomal recessive predisposition 16 | 1,442
aldosterone-producing adenoma 16 | 665
pediatric high grade glioma 16 | 1,064
Schizophrenia 15 | 1,160
Multiple myeloma 14 | 1,332
acute myeloid leukemia 14 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
dermatomyositis 14 | 966
Duchenne muscular dystrophy 13 | 601
Liver cancer 13 | 604
esophageal adenocarcinoma 13 | 737
medulloblastoma 13 | 720
astrocytoma 12 | 1,146
progressive supranuclear palsy 12 | 676
Rheumatoid arthritis 11 | 1,191
active ulcerative colitis 11 | 764
cutaneous lupus erythematosus 11 | 1,057
interstitial lung disease 11 | 298
nasopharyngeal carcinoma 11 | 1,058
Amyotrophic lateral sclerosis 10 | 451
Down syndrome 10 | 499
active Crohn's disease 10 | 922
fibroadenoma 10 | 559
Alzheimer's disease 9 | 658
Atopic dermatitis 9 | 952
Endometriosis 9 | 540
Intellectual disability 9 | 1,016
Muscle hypotonia 9 | 571
Waldenstrons macroglobulinemia 9 | 765
Blepharoptosis 8 | 231
Hypoplastic mandible condyle 8 | 275
Mandibular hypoplasia 8 | 275
Melanoma 8 | 711
Micrognathism 8 | 275
chronic rhinosinusitis 8 | 512
Acquired scoliosis 7 | 281
Bipolar Disorder 7 | 666
Breast Neoplasms 7 | 445
Cognitive delay 7 | 608
Curvature of spine 7 | 282
Endometrial cancer 7 | 311
Epilepsy 7 | 792
Global developmental delay 7 | 608
Hypertension 7 | 396
Mental and motor retardation 7 | 608
Obesity 7 | 678
Pectus excavatum 7 | 100
Weight Gain 7 | 100
hereditary spastic paraplegia 7 | 318
non primary Sjogren syndrome sicca 7 | 891
sonic hedgehog group medulloblastoma 7 | 467
Short stature 6 | 531
pancreatic carcinoma 6 | 562

Tissue

Endocrine System 207 | 18,159
Nervous System 206 | 16,725
Blood and immune system 205 | 16,909
Digestive Tract 205 | 17,369
Female tissues 205 | 17,400
Liver and Pancreas 204 | 16,750
Male tissues 204 | 17,142
Skin and soft tissues 204 | 17,230
Urinary Tract 204 | 16,678
Respiratory system 201 | 16,393
Cardiovascular System 190 | 15,192

Target Family

Non-IDG 135 | 12,091
Enzyme 36 | 4,145
Transcription Factor 11 | 1,400
Kinase 10 | 634
Ion Channel 7 | 344
GPCR 5 | 408
Transporter 4 | 473

Compartment GO Term

Actin filaments 208 | 208
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Protein WWC3 WWC3 Tbio Non-IDG -0.55831 4.90 66
One cut domain family member 2 ONECUT2 Tbio Transcription Factor -2.25163 169.5 107
Atrial natriuretic peptide-converting enzyme CORIN Tbio Non-IDG -2.14443 144.4 221
CTP synthase 1 CTPS1 Tbio Enzyme -2.29349 196.5 107
Signal-induced proliferation-associated 1-like protein 1 SIPA1L1 Tbio Non-IDG -0.56258 5.05 40
Transmembrane protein 17 TMEM17 Tbio Non-IDG 0.61 0.56 52
Leucine-rich repeat flightless-interacting protein 2 LRRFIP2 Tbio Non-IDG -0.65733 4.88 129
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283