Development Level

Tbio 125 | 11,651
Tchem 14 | 1,388
Tclin 8 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 9 | 499
embryonic lethality prior to t... 6 | 278
decreased body weight 5 | 161
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
decreased mean corpuscular vol... 3 | 79
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
increased circulating alkaline... 3 | 122
pallor 3 | 34
prenatal lethality prior to he... 3 | 87
abnormal coat appearance 2 | 31
abnormal embryo turning 2 | 31
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased spleen weight 2 | 10
edema 2 | 59
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating phosphat... 2 | 26
increased fasted circulating g... 2 | 76
increased mean corpuscular hem... 2 | 36
increased startle reflex 2 | 112
increased vertical activity 2 | 24
short tibia 2 | 97
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal chorioallantoic fusio... 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
female infertility 1 | 60
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
shortened RR interval 1 | 17
small testis 1 | 58
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

Carcinoma 116 | 11,493
ovarian cancer 96 | 8,520
osteosarcoma 84 | 7,950
psoriasis 77 | 6,694
Cancer 71 | 2,499
glioblastoma 71 | 5,792
atypical teratoid / rhabdoid tumor 60 | 5,112
ependymoma 60 | 4,679
Breast cancer 56 | 3,578
pancreatic cancer 55 | 2,398
medulloblastoma, large-cell 54 | 6,241
lung cancer 51 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 49 | 3,291
Astrocytoma, Pilocytic 48 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,989
Kidney cancer 41 | 2,613
lung carcinoma 41 | 2,843
invasive ductal carcinoma 38 | 2,951
lung adenocarcinoma 38 | 2,716
malignant mesothelioma 37 | 3,232
adult high grade glioma 36 | 3,801
non-small cell lung cancer 34 | 2,890
diabetes mellitus 32 | 1,728
subependymal giant cell astrocytoma 32 | 2,287
group 3 medulloblastoma 31 | 4,104
primitive neuroectodermal tumor 31 | 3,035
group 4 medulloblastoma 30 | 1,855
ulcerative colitis 30 | 1,819
tuberculosis 28 | 2,010
astrocytic glioma 27 | 2,597
interstitial cystitis 27 | 2,312
Liver Cirrhosis, Experimental 26 | 769
oligodendroglioma 26 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
spina bifida 26 | 1,074
Rheumatoid arthritis 25 | 1,191
primary pancreatic ductal adenocarcinoma 25 | 1,109
acute quadriplegic myopathy 24 | 1,158
colon cancer 24 | 1,478
cystic fibrosis 24 | 1,696
ductal carcinoma in situ 24 | 1,745
adrenocortical carcinoma 23 | 1,428
Duchenne muscular dystrophy 22 | 601
Schizophrenia 22 | 1,160
breast carcinoma 22 | 1,638
pituitary cancer 22 | 1,972
juvenile dermatomyositis 21 | 1,187
Alzheimer's disease 20 | 658
Kidney disease 20 | 430
Autosomal recessive predisposition 19 | 1,442
Heart disease 19 | 306
Osteoporosis 19 | 363
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 510
pediatric high grade glioma 18 | 1,064
Neoplasm Invasiveness 17 | 161
dermatomyositis 17 | 966
Liver cancer 16 | 604
Multiple myeloma 16 | 1,332
Pick disease 16 | 1,894
astrocytoma 16 | 1,146
Cerebrovascular disease 15 | 238
Myopathy 15 | 185
Stomach Neoplasms 15 | 300
Hypertension 14 | 396
Neoplasm Metastasis 14 | 168
pancreatic carcinoma 14 | 562
Down syndrome 13 | 499
Intellectual disability 13 | 1,016
Melanoma 13 | 711
Neuropathy 13 | 261
Obesity 13 | 678
Vascular disease 13 | 319
Breast Neoplasms 12 | 445
Endometrial cancer 12 | 311
Inflammatory bowel disease 12 | 151
Prostatic Neoplasms 12 | 495
Waldenstrons macroglobulinemia 12 | 765
gastric carcinoma 12 | 807
mucosa-associated lymphoid tissue lymphoma 12 | 484
Animal Mammary Neoplasms 11 | 136
Asthma 11 | 385
Becker muscular dystrophy 11 | 191
Bipolar Disorder 11 | 666
Cardiomyopathy 11 | 116
Mammary Neoplasms 11 | 425
Mammary Neoplasms, Animal 11 | 136
Mammary Neoplasms, Experimental 11 | 154
Neurodegenerative disease 11 | 414
acute myeloid leukemia 11 | 783
cutaneous lupus erythematosus 11 | 1,057
esophageal adenocarcinoma 11 | 737
hereditary spastic paraplegia 11 | 318
Blepharoptosis 10 | 231
Liver disease 10 | 237
Lung disease 10 | 142
Polycystic ovary syndrome 10 | 360
Toxic encephalopathy 10 | 141
hepatocellular carcinoma 10 | 547
medulloblastoma 10 | 720

Tissue

Blood and immune system 146 | 16,909
Endocrine System 146 | 18,159
Female tissues 146 | 17,400
Liver and Pancreas 146 | 16,750
Skin and soft tissues 146 | 17,230
Digestive Tract 145 | 17,369
Male tissues 145 | 17,142
Urinary Tract 145 | 16,678
Nervous System 144 | 16,725
Respiratory system 144 | 16,393
Cardiovascular System 138 | 15,192

Target Family

Non-IDG 119 | 12,091
Enzyme 13 | 4,145
Kinase 12 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408
Transporter 1 | 473

Compartment GO Term

Actin filament 148 | 148
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Actin filament-associated protein 1 AFAP1 Tbio Non-IDG -1.89567 70.0 314
Myosin light chain kinase, smooth muscle MYLK Tchem Kinase -2.81312 694.0 219
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Tropomodulin-1 TMOD1 Tbio Non-IDG -1.84485 74.1 155
Pro-epidermal growth factor EGF Tbio Non-IDG -3.75933 4903.2 978
Tropomodulin-4 TMOD4 Tbio Non-IDG -1.94209 70.0 114
Proto-oncogene vav VAV1 Tchem Non-IDG -2.66356 489.1 548
Tropomodulin-3 TMOD3 Tbio Non-IDG -1.07490 13.0 95
Actin-related protein 3 ACTR3 Tbio Non-IDG -1.28334 17.7 202
Protein phosphatase Slingshot homolog 1 SSH1 Tbio Enzyme -1.45823 27.6 148