Development Level

Tbio 119 | 11,178
Tchem 19 | 1,885
Tclin 8 | 612
Tdark 1 | 6,569

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 9 | 499
embryonic lethality prior to t... 6 | 278
decreased body weight 5 | 161
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
decreased mean corpuscular vol... 3 | 79
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
increased circulating alkaline... 3 | 122
pallor 3 | 34
prenatal lethality prior to he... 3 | 87
abnormal coat appearance 2 | 31
abnormal embryo turning 2 | 31
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased spleen weight 2 | 10
edema 2 | 59
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating phosphat... 2 | 26
increased fasted circulating g... 2 | 76
increased mean corpuscular hem... 2 | 36
increased startle reflex 2 | 112
increased vertical activity 2 | 24
short tibia 2 | 97
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal chorioallantoic fusio... 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
female infertility 1 | 60
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
shortened RR interval 1 | 17
small testis 1 | 58
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

Carcinoma 115 | 11,192
ovarian cancer 95 | 8,297
osteosarcoma 83 | 7,766
psoriasis 76 | 6,514
glioblastoma 71 | 5,635
Cancer 70 | 2,388
atypical teratoid / rhabdoid tumor 60 | 4,971
ependymoma 60 | 4,559
Breast cancer 55 | 3,469
pancreatic cancer 55 | 2,322
medulloblastoma, large-cell 54 | 6,086
lung cancer 51 | 4,607
intraductal papillary-mucinous neoplasm (IPMN) 49 | 3,204
Astrocytoma, Pilocytic 48 | 3,006
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,902
Kidney cancer 41 | 2,548
lung carcinoma 41 | 2,755
invasive ductal carcinoma 38 | 2,867
lung adenocarcinoma 38 | 2,627
malignant mesothelioma 37 | 3,135
adult high grade glioma 36 | 3,701
non-small cell lung cancer 34 | 2,799
diabetes mellitus 32 | 1,683
subependymal giant cell astrocytoma 32 | 2,230
group 3 medulloblastoma 31 | 4,002
primitive neuroectodermal tumor 31 | 2,957
group 4 medulloblastoma 30 | 1,806
ulcerative colitis 30 | 1,765
tuberculosis 28 | 1,963
astrocytic glioma 27 | 2,530
interstitial cystitis 27 | 2,237
Liver Cirrhosis, Experimental 26 | 733
oligodendroglioma 26 | 2,768
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,911
spina bifida 26 | 1,053
Rheumatoid arthritis 25 | 1,156
primary pancreatic ductal adenocarcinoma 25 | 1,071
acute quadriplegic myopathy 24 | 1,133
colon cancer 24 | 1,428
cystic fibrosis 24 | 1,629
ductal carcinoma in situ 24 | 1,686
adrenocortical carcinoma 23 | 1,385
Duchenne muscular dystrophy 22 | 587
Schizophrenia 22 | 1,136
breast carcinoma 22 | 1,589
pituitary cancer 22 | 1,915
juvenile dermatomyositis 21 | 1,147
Alzheimer's disease 20 | 640
Kidney disease 20 | 411
Autosomal recessive predisposition 19 | 1,407
Osteoporosis 19 | 348
Heart disease 18 | 288
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 492
pediatric high grade glioma 18 | 1,035
Neoplasm Invasiveness 17 | 151
dermatomyositis 17 | 941
Liver cancer 16 | 589
Multiple myeloma 16 | 1,296
Pick disease 16 | 1,856
astrocytoma 16 | 1,113
Cerebrovascular disease 15 | 223
Myopathy 15 | 185
Stomach Neoplasms 15 | 287
Hypertension 14 | 372
Neoplasm Metastasis 14 | 160
pancreatic carcinoma 14 | 555
Down syndrome 13 | 480
Intellectual disability 13 | 998
Melanoma 13 | 689
Neuropathy 13 | 254
Obesity 13 | 655
Breast Neoplasms 12 | 423
Endometrial cancer 12 | 301
Inflammatory bowel disease 12 | 148
Prostatic Neoplasms 12 | 472
Vascular disease 12 | 294
Waldenstrons macroglobulinemia 12 | 742
gastric carcinoma 12 | 781
mucosa-associated lymphoid tissue lymphoma 12 | 473
Animal Mammary Neoplasms 11 | 130
Asthma 11 | 370
Becker muscular dystrophy 11 | 184
Bipolar Disorder 11 | 646
Cardiomyopathy 11 | 116
Mammary Neoplasms 11 | 403
Mammary Neoplasms, Animal 11 | 130
Mammary Neoplasms, Experimental 11 | 147
Neurodegenerative disease 11 | 402
acute myeloid leukemia 11 | 760
cutaneous lupus erythematosus 11 | 1,016
esophageal adenocarcinoma 11 | 696
hereditary spastic paraplegia 11 | 313
Blepharoptosis 10 | 229
Liver disease 10 | 227
Lung disease 10 | 135
Polycystic ovary syndrome 10 | 348
Toxic encephalopathy 10 | 139
hepatocellular carcinoma 10 | 536
medulloblastoma 10 | 702

Tissue

Blood and immune system 145 | 16,909
Endocrine System 145 | 18,159
Female tissues 145 | 17,400
Liver and Pancreas 145 | 16,750
Skin and soft tissues 145 | 17,230
Digestive Tract 144 | 17,369
Male tissues 144 | 17,142
Urinary Tract 144 | 16,678
Nervous System 143 | 16,725
Respiratory system 143 | 16,393
Cardiovascular System 137 | 15,192

Target Family

Non-IDG 119 | 12,091
Enzyme 13 | 4,145
Kinase 12 | 634
GPCR 1 | 408
Transcription Factor 1 | 1,400
Transporter 1 | 473

Compartment GO Term

Actin filament 147 | 147
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vinculin VCL Tbio Non-IDG -3.34872 2107.1 637
Afadin AFDN Tbio Non-IDG -2.16280 151.2 200
Plectin PLEC Tbio Non-IDG -2.50749 337.2 130
Ras GTPase-activating-like protein IQGAP1 IQGAP1 Tbio Enzyme -2.27732 224.8 291
Utrophin UTRN Tbio Non-IDG -2.63658 425.0 37
Rho-related GTP-binding protein RhoQ RHOQ Tbio Enzyme -1.48059 28.3 111
Gelsolin GSN Tbio Non-IDG -3.11676 1340.4 481
Putative annexin A2-like protein ANXA2P2 Tdark Non-IDG -2.68290 825.4 0
Anillin ANLN Tbio Non-IDG -2.40271 193.5 150
Espin ESPN Tbio Non-IDG -2.01425 100.4 63