Development Level

Tbio 114 | 10,625
Tchem 20 | 1,890
Tdark 7 | 7,003
Tclin 6 | 602

IMPC Term

preweaning lethality, incomple... 8 | 260
embryonic lethality prior to t... 6 | 187
preweaning lethality, complete... 6 | 633
decreased mean corpuscular vol... 4 | 50
abnormal embryo size 3 | 112
decreased body weight 3 | 174
decreased circulating insulin ... 3 | 75
decreased total body fat amoun... 3 | 186
abnormal retina morphology 2 | 100
decreased bone mineral content 2 | 157
decreased circulating HDL chol... 2 | 77
decreased circulating LDL chol... 2 | 37
decreased circulating choleste... 2 | 85
decreased circulating creatini... 2 | 31
decreased circulating fructosa... 2 | 31
decreased lean body mass 2 | 195
increased circulating alkaline... 2 | 119
increased circulating phosphat... 2 | 24
increased mean corpuscular hem... 2 | 93
increased mean corpuscular hem... 2 | 25
increased or absent threshold ... 2 | 128
prenatal lethality prior to he... 2 | 64
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal craniofacial morpholo... 1 | 12
abnormal digestive system phys... 1 | 1
abnormal embryo turning 1 | 15
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal motor learning 1 | 4
abnormal pericardium morpholog... 1 | 11
abnormal posture 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal vertebrae morphology 1 | 14
absent pinna reflex 1 | 21
decreased NK T cell number 1 | 28
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating free fat... 1 | 39
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased hematocrit 1 | 25
decreased lumbar vertebrae num... 1 | 62
decreased lymphocyte cell numb... 1 | 9
decreased mean corpuscular hem... 1 | 34
decreased mean platelet volume 1 | 12
decreased monocyte cell number 1 | 28
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased total retina thickne... 1 | 20
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
enlarged epididymis 1 | 27
enlarged heart 1 | 111
female infertility 1 | 34
fused cornea and lens 1 | 4
hydrops fetalis 1 | 22
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating amylase ... 1 | 13
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart rate 1 | 17
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased neutrophil cell numb... 1 | 15
increased red blood cell distr... 1 | 21
increased vertical activity 1 | 18
microphthalmia 1 | 15
pallor 1 | 13
shortened RR interval 1 | 19

Disease

ovarian cancer 92 | 8,484
osteosarcoma 83 | 7,933
psoriasis 75 | 6,685
glioblastoma 70 | 5,572
Cancer 67 | 2,346
medulloblastoma, large-cell 56 | 6,234
pancreatic cancer 55 | 2,300
atypical teratoid / rhabdoid tumor 52 | 4,369
pilocytic astrocytoma 49 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 48 | 3,289
Breast cancer 47 | 3,094
lung cancer 47 | 4,466
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 42 | 2,988
lung carcinoma 41 | 2,844
invasive ductal carcinoma 38 | 2,950
pediatric high grade glioma 38 | 2,712
lung adenocarcinoma 37 | 2,713
ulcerative colitis 36 | 2,087
Carcinoma 35 | 2,147
primitive neuroectodermal tumor 34 | 3,031
malignant mesothelioma 32 | 3,162
subependymal giant cell astrocytoma 32 | 2,287
group 4 medulloblastoma 31 | 1,875
primary pancreatic ductal adenocarcinoma 31 | 1,271
non-small cell lung cancer 30 | 2,798
diabetes mellitus 29 | 1,663
ependymoma 28 | 2,514
tuberculosis 28 | 1,557
cystic fibrosis 27 | 1,665
oligodendroglioma 27 | 2,849
interstitial cystitis 26 | 2,299
posterior fossa group A ependymoma 26 | 1,511
colon cancer 24 | 1,475
ductal carcinoma in situ 24 | 1,745
spina bifida 24 | 1,064
Rheumatoid Arthritis 23 | 1,160
acute quadriplegic myopathy 23 | 1,157
adrenocortical carcinoma 23 | 1,427
astrocytoma 23 | 1,493
pituitary cancer 23 | 1,972
Duchenne muscular dystrophy 22 | 602
astrocytic glioma 21 | 2,241
juvenile dermatomyositis 21 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,795
Kidney disease 20 | 396
medulloblastoma 19 | 1,524
adult high grade glioma 18 | 2,148
breast carcinoma 18 | 1,614
dermatomyositis 18 | 933
sonic hedgehog group medulloblastoma 18 | 1,482
Alzheimer's disease 17 | 644
Osteoporosis 17 | 257
Myopathy 16 | 128
autosomal dominant Emery-Dreifuss muscular dystrophy 16 | 499
pancreatic carcinoma 16 | 567
Cerebrovascular disease 15 | 231
Heart disease 15 | 279
Multiple myeloma 15 | 1,327
Neoplasm Invasiveness 15 | 127
Pick disease 15 | 1,893
gastric carcinoma 15 | 832
posterior fossa group B ependymoma 15 | 1,530
atypical teratoid/rhabdoid tumor 14 | 1,095
Cardiomyopathy 13 | 110
Down syndrome 13 | 548
Inflammatory bowel disease 13 | 142
group 3 medulloblastoma 13 | 2,254
Becker muscular dystrophy 12 | 187
Hypertension 12 | 287
Neoplasm Metastasis 12 | 138
Neuropathy 12 | 210
Prostatic Neoplasms 12 | 471
Animal Mammary Neoplasms 11 | 136
Asthma 11 | 349
Endometriosis 11 | 535
Mammary Neoplasms 11 | 410
Neurodegenerative disease 11 | 383
Obesity 11 | 616
Vascular disease 11 | 281
Waldenstrons macroglobulinemia 11 | 765
mucosa-associated lymphoid tissue lymphoma 11 | 480
Liver disease 10 | 219
Lung disease 10 | 132
Mammary Neoplasms, Experimental 10 | 150
Multiple Sclerosis 10 | 498
Stomach Neoplasms 10 | 282
acute myeloid leukemia 10 | 780
cutaneous lupus erythematosus 10 | 1,056
esophageal adenocarcinoma 10 | 737
hepatocellular carcinoma 10 | 532
Amyotrophic Lateral Sclerosis 9 | 431
Coronary artery disease 9 | 240
IGA Glomerulonephritis 9 | 454
Polycystic Ovary Syndrome 9 | 332
fibroadenoma 9 | 557
gastric cancer 9 | 430
hereditary spastic paraplegia 9 | 313
nasopharyngeal carcinoma 9 | 1,056
primary Sjogren syndrome 9 | 789

Tissue

Blood and immune system 146 | 17,995
Cardiovascular System 146 | 17,958
Digestive Tract 146 | 18,473
Endocrine System 146 | 18,512
Female tissues 146 | 18,647
Liver and Pancreas 146 | 18,136
Male tissues 146 | 17,969
Nervous System 146 | 18,561
Urinary Tract 146 | 18,444
Respiratory system 145 | 17,484
Skin and soft tissues 145 | 18,115

Target Family

Non-IDG 120 | 11,971
Enzyme 13 | 4,146
Kinase 10 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 406
Transporter 1 | 473

Compartment GO Term

Actin filament 147 | 147
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Actin-related protein 2 ACTR2 Tchem Non-IDG -1.84526 72.5 184
Actin-related protein 3 ACTR3 Tbio Non-IDG -1.25542 16.8 169
Protein phosphatase Slingshot homolog 1 SSH1 Tbio Enzyme -1.41770 25.0 106
Radixin RDX Tbio Non-IDG -2.45592 216.9 310
WD repeat-containing protein 1 WDR1 Tbio Non-IDG -1.58081 43.3 85
Transforming protein RhoA RHOA Tbio Enzyme -3.48838 3096.5 467
Rho-associated protein kinase 2 ROCK2 Tclin Kinase -2.39656 248.3 472
Cytospin-B SPECC1 Tbio Non-IDG -1.92936 84.6 159