Development Level

Tbio 376 | 10,625
Tchem 83 | 1,890
Tdark 43 | 7,003
Tclin 18 | 602

Collection

Eligible Ion Channel Proteins 2 | 117
Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 31 | 633
preweaning lethality, incomple... 16 | 260
abnormal behavior 11 | 226
embryonic lethality prior to t... 9 | 187
abnormal embryo size 7 | 112
decreased body weight 7 | 174
decreased circulating HDL chol... 7 | 77
decreased circulating choleste... 7 | 85
decreased grip strength 7 | 123
decreased lean body mass 7 | 195
hyperactivity 7 | 108
abnormal bone structure 6 | 131
abnormal retina morphology 6 | 100
decreased bone mineral content 6 | 157
decreased total body fat amoun... 6 | 186
increased circulating alkaline... 6 | 119
decreased circulating glucose ... 5 | 121
decreased mean corpuscular vol... 5 | 50
increased body weight 5 | 42
increased heart weight 5 | 37
increased or absent threshold ... 5 | 128
abnormal behavioral response t... 4 | 52
abnormal coat/hair pigmentatio... 4 | 54
abnormal sleep behavior 4 | 63
decreased circulating creatini... 4 | 31
decreased circulating triglyce... 4 | 83
decreased startle reflex 4 | 48
embryonic lethality prior to o... 4 | 148
enlarged heart 4 | 111
increased blood urea nitrogen ... 4 | 44
increased circulating chloride... 4 | 43
abnormal bone mineralization 3 | 55
abnormal locomotor activation 3 | 26
absent startle reflex 3 | 15
decreased body length 3 | 108
decreased bone mineral density 3 | 126
decreased circulating LDL chol... 3 | 37
decreased circulating alanine ... 3 | 53
decreased circulating free fat... 3 | 39
decreased circulating fructosa... 3 | 31
decreased circulating insulin ... 3 | 75
decreased circulating serum al... 3 | 79
decreased leukocyte cell numbe... 3 | 54
hypoactivity 3 | 89
improved glucose tolerance 3 | 56
increased circulating calcium ... 3 | 32
increased circulating phosphat... 3 | 24
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 107
limb grasping 3 | 35
prenatal lethality prior to he... 3 | 64
short tibia 3 | 82
abnormal QRS complex 2 | 25
abnormal cornea morphology 2 | 24
abnormal forebrain development 2 | 18
abnormal gait 2 | 51
abnormal head morphology 2 | 10
abnormal hindbrain development 2 | 24
abnormal midbrain development 2 | 22
abnormal neural tube closure 2 | 37
abnormal pericardium morpholog... 2 | 11
abnormal respiratory quotient 2 | 9
abnormal retinal pigmentation 2 | 61
abnormal skin morphology 2 | 23
abnormal vibrissa morphology 2 | 17
abnormal vocalization 2 | 21
absent heartbeat 2 | 6
absent pinna reflex 2 | 21
cataract 2 | 26
convulsive seizures 2 | 11
decreased Ly6C low monocyte nu... 2 | 23
decreased circulating calcium ... 2 | 33
decreased circulating glycerol... 2 | 19
decreased circulating iron lev... 2 | 25
decreased circulating total pr... 2 | 41
decreased fasted circulating g... 2 | 49
decreased heart weight 2 | 44
decreased hematocrit 2 | 25
decreased monocyte cell number 2 | 28
decreased prepulse inhibition 2 | 52
decreased vertical activity 2 | 22
increased NK T cell number 2 | 11
increased body length 2 | 20
increased bone mineral density 2 | 52
increased circulating creatini... 2 | 29
increased circulating iron lev... 2 | 25
increased circulating total pr... 2 | 20
increased erythrocyte cell num... 2 | 26
increased fasted circulating g... 2 | 68
increased heart rate 2 | 17
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 93
increased mean corpuscular hem... 2 | 25
increased mean corpuscular vol... 2 | 91
increased red blood cell distr... 2 | 21
increased total body fat amoun... 2 | 57
increased vertical activity 2 | 18
pallor 2 | 13
persistence of hyaloid vascula... 2 | 22
polycystic kidney 2 | 9

Disease

ovarian cancer 285 | 8,484
osteosarcoma 271 | 7,933
psoriasis 231 | 6,685
glioblastoma 227 | 5,572
medulloblastoma, large-cell 200 | 6,234
lung cancer 172 | 4,466
Cancer 166 | 2,346
atypical teratoid / rhabdoid tumor 166 | 4,369
malignant mesothelioma 145 | 3,162
pancreatic cancer 141 | 2,300
pilocytic astrocytoma 138 | 3,086
Breast cancer 136 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 136 | 3,289
invasive ductal carcinoma 134 | 2,950
Carcinoma 128 | 2,147
intraductal papillary-mucinous adenoma (IPMA) 126 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 125 | 2,988
pediatric high grade glioma 123 | 2,712
primitive neuroectodermal tumor 123 | 3,031
non-small cell lung cancer 121 | 2,798
lung adenocarcinoma 110 | 2,713
lung carcinoma 109 | 2,844
subependymal giant cell astrocytoma 106 | 2,287
diabetes mellitus 101 | 1,663
ependymoma 101 | 2,514
oligodendroglioma 101 | 2,849
primary pancreatic ductal adenocarcinoma 95 | 1,271
ductal carcinoma in situ 89 | 1,745
breast carcinoma 83 | 1,614
group 4 medulloblastoma 83 | 1,875
cystic fibrosis 82 | 1,665
ulcerative colitis 81 | 2,087
astrocytic glioma 80 | 2,241
interstitial cystitis 80 | 2,299
acute quadriplegic myopathy 79 | 1,157
colon cancer 76 | 1,475
pituitary cancer 73 | 1,972
adult high grade glioma 68 | 2,148
juvenile dermatomyositis 68 | 1,189
posterior fossa group A ependymoma 65 | 1,511
adrenocortical carcinoma 63 | 1,427
astrocytoma 62 | 1,493
tuberculosis 62 | 1,557
medulloblastoma 61 | 1,524
Duchenne muscular dystrophy 58 | 602
Pick disease 56 | 1,893
spina bifida 55 | 1,064
group 3 medulloblastoma 54 | 2,254
sonic hedgehog group medulloblastoma 54 | 1,482
Heart disease 52 | 279
Alzheimer's disease 51 | 644
Kidney disease 51 | 396
Rheumatoid Arthritis 50 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 50 | 499
pancreatic ductal adenocarcinoma liver metastasis 49 | 1,795
dermatomyositis 47 | 933
gastric carcinoma 47 | 832
posterior fossa group B ependymoma 44 | 1,530
Cerebrovascular disease 41 | 231
atypical teratoid/rhabdoid tumor 40 | 1,095
Hypertension 39 | 287
Multiple myeloma 39 | 1,327
Obesity 38 | 616
cutaneous lupus erythematosus 38 | 1,056
esophageal adenocarcinoma 38 | 737
Myopathy 37 | 128
Waldenstrons macroglobulinemia 37 | 765
Mammary Neoplasms 36 | 410
Coronary artery disease 35 | 240
Down syndrome 34 | 548
nasopharyngeal carcinoma 33 | 1,056
pancreatic carcinoma 33 | 567
Amyotrophic Lateral Sclerosis 32 | 431
Atherosclerosis 32 | 275
Endometriosis 31 | 535
Prostatic Neoplasms 31 | 471
Osteoporosis 30 | 257
fibroadenoma 30 | 557
Cardiomyopathy 29 | 110
Vascular disease 29 | 281
Neoplasm Invasiveness 28 | 127
Neoplasm Metastasis 28 | 138
hepatocellular carcinoma 28 | 532
non primary Sjogren syndrome sicca 28 | 840
primary Sjogren syndrome 28 | 789
Liver carcinoma 27 | 217
Neuropathy 27 | 210
tuberculosis and treatment for 6 months 27 | 686
Becker muscular dystrophy 26 | 187
Liver disease 26 | 219
Lung disease 26 | 132
acute myeloid leukemia 26 | 780
aldosterone-producing adenoma 26 | 664
gastric cancer 26 | 430
mucosa-associated lymphoid tissue lymphoma 26 | 480
Atopic dermatitis 25 | 944
Stomach Neoplasms 25 | 282
active Crohn's disease 25 | 918
Asthma 24 | 349
progressive supranuclear palsy 24 | 674

Tissue

Female tissues 517 | 18,647
Liver and Pancreas 517 | 18,136
Nervous System 517 | 18,561
Digestive Tract 516 | 18,473
Endocrine System 516 | 18,512
Blood and immune system 515 | 17,995
Cardiovascular System 515 | 17,958
Male tissues 515 | 17,969
Urinary Tract 514 | 18,444
Skin and soft tissues 511 | 18,115
Respiratory system 510 | 17,484

Target Family

Non-IDG 384 | 11,971
Enzyme 68 | 4,146
Kinase 33 | 634
Transcription Factor 22 | 1,400
Transporter 5 | 473
Ion Channel 4 | 341
GPCR 3 | 406
Nuclear Receptor 1 | 48

Compartment GO Term

Actin cytoskeleton 520 | 520
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tchem Transporter -3.30074 2066.8 474
F-actin-capping protein subunit alpha-1 CAPZA1 Tbio Non-IDG -1.28182 20.1 139
Filensin BFSP1 Tbio Non-IDG -2.08549 124.5 154
Myosin light chain 6B MYL6B Tdark Non-IDG -0.43175 2.57 113
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
CD5 antigen-like CD5L Tbio Non-IDG -1.78447 64.4 287