Development Level

Tbio 82 | 11,445
Tclin 16 | 613
Tchem 15 | 1,598
Tdark 6 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 19 | 979
embryonic lethality prior to o... 8 | 239
embryonic lethality prior to t... 8 | 278
increased leukocyte cell numbe... 4 | 47
abnormal seminal vesicle morph... 3 | 114
cardiovascular system phenotyp... 3 | 36
hypoactivity 3 | 132
male infertility 3 | 123
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal kidney morphology 2 | 65
abnormal vibrissa morphology 2 | 25
decreased circulating alkaline... 2 | 46
decreased prepulse inhibition 2 | 82
female infertility 2 | 60
hyperactivity 2 | 148
increased fasted circulating g... 2 | 76
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal sensory capabilities-... 1 | 8
abnormal skin morphology 1 | 50
abnormal tail morphology 1 | 25
abnormal vocalization 1 | 21
absent vibrissae 1 | 12
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased fluid intake 1 | 3
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased heart rate 1 | 23
increased heart rate variabili... 1 | 7
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
protruding tongue 1 | 3
short tibia 1 | 97
shortened RR interval 1 | 17
shortened ST segment 1 | 10
small adrenal glands 1 | 16
small lymph nodes 1 | 1
small testis 1 | 58

Disease

Carcinoma 80 | 11,493
ovarian cancer 69 | 8,520
psoriasis 52 | 6,694
glioblastoma 45 | 5,792
osteosarcoma 45 | 7,950
medulloblastoma, large-cell 43 | 6,241
atypical teratoid / rhabdoid tumor 39 | 5,112
Cancer 33 | 2,499
Breast cancer 31 | 3,578
ependymoma 31 | 4,679
Kidney cancer 30 | 2,613
Pick disease 30 | 1,894
lung cancer 30 | 4,740
primitive neuroectodermal tumor 29 | 3,035
group 3 medulloblastoma 28 | 4,104
adult high grade glioma 26 | 3,801
Epilepsy 24 | 792
diabetes mellitus 24 | 1,728
Multiple myeloma 23 | 1,332
oligodendroglioma 23 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
lung adenocarcinoma 22 | 2,716
subependymal giant cell astrocytoma 21 | 2,287
Hypertension 20 | 396
astrocytic glioma 20 | 2,597
Astrocytoma, Pilocytic 18 | 3,081
Seizures 18 | 596
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
malignant mesothelioma 18 | 3,232
Autosomal recessive predisposition 17 | 1,442
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
invasive ductal carcinoma 17 | 2,951
lung carcinoma 17 | 2,843
pituitary cancer 16 | 1,972
Adenoma 15 | 167
Anemia 14 | 365
Heart disease 14 | 306
colon cancer 14 | 1,478
Depressive disorder 13 | 409
cystic fibrosis 13 | 1,696
non-small cell lung cancer 13 | 2,890
Alzheimer's disease 12 | 658
Neurodegenerative disease 12 | 414
Waldenstrons macroglobulinemia 12 | 765
pancreatic cancer 12 | 2,398
Atrial Fibrillation 11 | 124
Lynch syndrome 11 | 35
Muscle hypotonia 11 | 571
Osteoporosis 11 | 363
Parkinson's disease 11 | 392
Schizophrenia 11 | 1,160
astrocytoma 11 | 1,146
tuberculosis 11 | 2,010
Cerebrovascular disease 10 | 238
Constipation 10 | 181
Dementia 10 | 175
Intellectual disability 10 | 1,016
Kidney disease 10 | 430
Anxiety 9 | 136
Anxiety disease 9 | 113
Bipolar Disorder 9 | 666
Chronic heart failure 9 | 46
Coronary artery disease 9 | 268
Familial adenomatous polyposis 9 | 32
Fatigue 9 | 182
Hypertensive disease 9 | 292
Osteopetrosis 9 | 43
breast carcinoma 9 | 1,638
dermatomyositis 9 | 966
medulloblastoma 9 | 720
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Congestive heart failure 8 | 113
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Metabolic acidosis 8 | 90
Poisoning by digitalis glycoside 8 | 8
Poor school performance 8 | 645
Rheumatoid arthritis 8 | 1,191
Sebaceous adenoma 8 | 26
Short stature 8 | 531
Weight decreased 8 | 103
acute quadriplegic myopathy 8 | 1,158
hepatocellular carcinoma 8 | 547
interstitial cystitis 8 | 2,312
Arthritis 7 | 290
Attention deficit hyperactivity disorder 7 | 278
Cognitive delay 7 | 608
Endometrial cancer 7 | 311
Failure to gain weight 7 | 365
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Myopathy 7 | 185
Pediatric failure to thrive 7 | 365
ductal carcinoma in situ 7 | 1,745
nasopharyngeal carcinoma 7 | 1,058
pancreatic carcinoma 7 | 562
pediatric high grade glioma 7 | 1,064
ulcerative colitis 7 | 1,819

Tissue

Digestive Tract 114 | 17,369
Endocrine System 114 | 18,159
Urinary Tract 114 | 16,678
Female tissues 113 | 17,400
Male tissues 113 | 17,142
Nervous System 113 | 16,725
Skin and soft tissues 112 | 17,230
Liver and Pancreas 111 | 16,750
Blood and immune system 110 | 16,909
Respiratory system 109 | 16,393
Cardiovascular System 106 | 15,192

Target Family

Enzyme 46 | 4,145
Non-IDG 31 | 12,091
Transporter 31 | 473
Ion Channel 5 | 344
Epigenetic 3 | 242
Kinase 2 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

ATPase complex 119 | 119
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

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