Development Level

Tbio 73 | 10,625
Tchem 13 | 1,890
Tclin 13 | 602
Tdark 7 | 7,003

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 14 | 633
embryonic lethality prior to o... 7 | 148
embryonic lethality prior to t... 7 | 187
abnormal seminal vesicle morph... 3 | 47
hypoactivity 3 | 89
abnormal behavior 2 | 226
abnormal epididymis morphology 2 | 31
abnormal kidney morphology 2 | 30
abnormal retinal pigmentation 2 | 61
abnormal skin morphology 2 | 23
absent vibrissae 2 | 14
cardiovascular system phenotyp... 2 | 35
decreased circulating HDL chol... 2 | 77
decreased mean corpuscular vol... 2 | 50
decreased prepulse inhibition 2 | 52
decreased total body fat amoun... 2 | 186
enlarged epididymis 2 | 27
impaired glucose tolerance 2 | 52
increased fasted circulating g... 2 | 68
increased leukocyte cell numbe... 2 | 37
preweaning lethality, incomple... 2 | 260
short tibia 2 | 82
abnormal body wall morphology 1 | 7
abnormal embryo size 1 | 112
abnormal response to new envir... 1 | 8
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal sensory capabilities/... 1 | 3
abnormal vibrissa morphology 1 | 17
abnormal vocalization 1 | 21
cataract 1 | 26
decreased blood urea nitrogen ... 1 | 31
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating amylase ... 1 | 24
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased memory-marker CD4-po... 1 | 4
enlarged spleen 1 | 26
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased B cell number 1 | 23
increased NK T cell number 1 | 11
increased T cell number 1 | 15
increased body length 1 | 20
increased bone mineral density 1 | 52
increased caudal vertebrae num... 1 | 8
increased eosinophil cell numb... 1 | 9
increased gamma-delta T cell n... 1 | 16
increased heart rate variabili... 1 | 4
increased heart weight 1 | 37
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
increased startle reflex 1 | 38
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
protruding tongue 1 | 1
small adrenal glands 1 | 15
small lymph nodes 1 | 1
small testis 1 | 37
straub tail 1 | 26

Disease

ovarian cancer 58 | 8,484
psoriasis 46 | 6,685
medulloblastoma, large-cell 41 | 6,234
osteosarcoma 40 | 7,933
glioblastoma 36 | 5,572
atypical teratoid / rhabdoid tumor 30 | 4,369
Cancer 29 | 2,346
Pick disease 28 | 1,893
lung cancer 28 | 4,466
primitive neuroectodermal tumor 27 | 3,031
oligodendroglioma 23 | 2,849
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,289
subependymal giant cell astrocytoma 21 | 2,287
Breast cancer 20 | 3,094
Carcinoma 20 | 2,147
Multiple myeloma 20 | 1,327
diabetes mellitus 20 | 1,663
ependymoma 20 | 2,514
lung adenocarcinoma 20 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
lung carcinoma 18 | 2,844
pilocytic astrocytoma 18 | 3,086
adult high grade glioma 17 | 2,148
astrocytoma 17 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
pediatric high grade glioma 16 | 2,712
Hypertension 15 | 287
astrocytic glioma 15 | 2,241
invasive ductal carcinoma 15 | 2,950
malignant mesothelioma 15 | 3,162
Adenoma 14 | 165
cystic fibrosis 14 | 1,665
medulloblastoma 14 | 1,524
pituitary cancer 14 | 1,972
Neurodegenerative disease 13 | 383
colon cancer 13 | 1,475
sonic hedgehog group medulloblastoma 13 | 1,482
Heart disease 12 | 279
Parkinson's disease 11 | 364
non-small cell lung cancer 11 | 2,798
Coronary artery disease 10 | 240
Kidney disease 10 | 396
Lynch syndrome 10 | 33
Waldenstrons macroglobulinemia 10 | 765
atypical teratoid/rhabdoid tumor 10 | 1,095
Alzheimer's disease 9 | 644
Anemia 9 | 252
Chronic heart failure 9 | 46
Familial adenomatous polyposis 9 | 31
group 3 medulloblastoma 9 | 2,254
interstitial cystitis 9 | 2,299
pancreatic cancer 9 | 2,300
tuberculosis 9 | 1,557
Atrial Fibrillation 8 | 110
Cerebrovascular disease 8 | 231
Congestive heart failure 8 | 30
Metabolic acidosis 8 | 49
Osteopetrosis 8 | 40
Poisoning by digitalis glycoside 8 | 8
Sebaceous adenoma 8 | 11
acute quadriplegic myopathy 8 | 1,157
dermatomyositis 8 | 933
ulcerative colitis 8 | 2,087
Diarrhea 7 | 155
Gaucher disease type 1 7 | 171
Hypertensive disease 7 | 193
Osteoporosis 7 | 257
Primary cutaneous amyloidosis 7 | 26
Rheumatoid Arthritis 7 | 1,160
hepatocellular carcinoma 7 | 532
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
posterior fossa group B ependymoma 7 | 1,530
Dementia 6 | 129
Epilepsy 6 | 346
IGA Glomerulonephritis 6 | 454
Myopathy 6 | 128
Neuropathy 6 | 210
Prostatic Neoplasms 6 | 471
acute myeloid leukemia 6 | 780
ductal carcinoma in situ 6 | 1,745
nasopharyngeal carcinoma 6 | 1,056
pancreatic carcinoma 6 | 567
Amyotrophic Lateral Sclerosis 5 | 431
Arthritis 5 | 248
Atherosclerosis 5 | 275
Barrett's esophagus 5 | 183
Cockayne syndrome 5 | 54
Colorectal Neoplasms 5 | 217
Down syndrome 5 | 548
Heart failure 5 | 80
Hypersensitivity reaction type II disease 5 | 235
Inflammatory bowel disease 5 | 142
Intellectual disability 5 | 573
Migraine 5 | 79
Obesity 5 | 616
Schizophrenia 5 | 501
adrenocortical carcinoma 5 | 1,427
breast carcinoma 5 | 1,614
juvenile dermatomyositis 5 | 1,189
progressive supranuclear palsy 5 | 674

Tissue

Cardiovascular System 102 | 17,958
Digestive Tract 102 | 18,473
Male tissues 102 | 17,969
Nervous System 102 | 18,561
Skin and soft tissues 102 | 18,115
Urinary Tract 102 | 18,444
Blood and immune system 101 | 17,995
Endocrine System 101 | 18,512
Female tissues 101 | 18,647
Liver and Pancreas 101 | 18,136
Respiratory system 100 | 17,484

Target Family

Enzyme 40 | 4,146
Transporter 30 | 473
Non-IDG 26 | 11,971
Ion Channel 4 | 341
Epigenetic 3 | 242
Kinase 2 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

ATPase complex 106 | 106
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cardiac phospholamban PLN Tbio Non-IDG -1.89899 84.7 326
ATP-binding cassette sub-family A member 2 ABCA2 Tbio Transporter -1.41708 32.2 125
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.80191 64.7 120
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
V-type proton ATPase 116 kDa subunit a isoform 1 ATP6V0A1 Tbio Enzyme -1.36455 23.7 59
Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2 Tclin Transporter -2.04732 117.9 108
ATP-binding cassette sub-family A member 7 ABCA7 Tbio Transporter -2.14140 148.7 123
Sodium/potassium-transporting ATPase subunit alpha-3 ATP1A3 Tclin Transporter -2.09703 131.9 103
MutS protein homolog 4 MSH4 Tbio Non-IDG -1.85039 70.8 78
V-type proton ATPase subunit E 1 ATP6V1E1 Tbio Enzyme -0.98803 10.3 111