Development Level

Tbio 36 | 11,445
Tdark 9 | 6,588
Tchem 2 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

hyperactivity 3 | 148
increased or absent threshold ... 3 | 101
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
cardiovascular system phenotyp... 2 | 36
decreased mean corpuscular hem... 2 | 50
enlarged heart 2 | 210
increased lean body mass 2 | 172
increased prepulse inhibition 2 | 32
preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal cecum morphology 1 | 7
abnormal femur morphology 1 | 14
abnormal heart shape 1 | 5
abnormal kidney morphology 1 | 65
abnormal nail morphology 1 | 8
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
absent adrenal gland 1 | 2
absent pinna reflex 1 | 23
decreased cardiac output 1 | 3
decreased cardiac stroke volum... 1 | 6
decreased circulating calcium ... 1 | 36
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased respiratory quotient 1 | 16
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
enlarged spleen 1 | 41
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating free fat... 1 | 20
increased coping response 1 | 4
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased startle reflex 1 | 112
limb grasping 1 | 41
male infertility 1 | 123
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 37 | 11,493
ovarian cancer 27 | 8,520
osteosarcoma 23 | 7,950
medulloblastoma, large-cell 19 | 6,241
atypical teratoid / rhabdoid tumor 15 | 5,112
psoriasis 15 | 6,694
glioblastoma 14 | 5,792
ependymoma 13 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
malignant mesothelioma 12 | 3,232
adult high grade glioma 11 | 3,801
Cataract 8 multiple types 10 | 33
Pick disease 10 | 1,894
group 3 medulloblastoma 10 | 4,104
subependymal giant cell astrocytoma 10 | 2,287
astrocytic glioma 9 | 2,597
oligodendroglioma 9 | 2,850
Astrocytoma, Pilocytic 8 | 3,081
Autosomal recessive predisposition 8 | 1,442
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
lung cancer 8 | 4,740
primitive neuroectodermal tumor 8 | 3,035
Intellectual disability 7 | 1,016
Kidney cancer 7 | 2,613
diabetes mellitus 7 | 1,728
interstitial cystitis 7 | 2,312
non-small cell lung cancer 7 | 2,890
pituitary cancer 7 | 1,972
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Neurodegenerative disease 6 | 414
Paraplegia 6 | 74
group 4 medulloblastoma 6 | 1,855
hereditary spastic paraplegia 6 | 318
invasive ductal carcinoma 6 | 2,951
lung carcinoma 6 | 2,843
tuberculosis 6 | 2,010
Alzheimer's disease 5 | 658
Coarse facial features 5 | 108
Mucoepidermoid carcinoma 5 | 26
Prenatal onset 5 | 139
Rheumatoid arthritis 5 | 1,191
Spastic Paraplegia 5 | 42
Thickened facial skin with coarse facial features 5 | 108
dermatomyositis 5 | 966
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Babinski Reflex 4 | 100
Breast cancer 4 | 3,578
Bulbous nasal tip 4 | 48
Bulbous nose 4 | 48
Cancer 4 | 2,499
Cerebral palsy 4 | 40
Dilated ventricles (finding) 4 | 121
Epilepsy 4 | 792
Horner's syndrome 4 | 11
Hyperreflexia 4 | 209
Liver cancer 4 | 604
Macrostomia 4 | 72
Microcephaly 4 | 166
Multiple myeloma 4 | 1,332
Pain agnosia 4 | 104
Potato nose 4 | 48
Quadriplegia 4 | 20
Severe mental retardation (I.Q. 20-34) 4 | 99
Short philtrum 4 | 53
Small head 4 | 374
colon cancer 4 | 1,478
lung adenocarcinoma 4 | 2,716
Congenital clubfoot 3 | 109
Liver Cirrhosis, Experimental 3 | 769
Narrow forehead 3 | 34
Neonatal Hypotonia 3 | 64
Seizures 3 | 596
Waldenstrons macroglobulinemia 3 | 765
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
pancreatic cancer 3 | 2,398
pediatric high grade glioma 3 | 1,064
posterior fossa group B ependymoma 3 | 416
ulcerative colitis 3 | 1,819
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Kidney disease 2 | 430
Nasal bridge wide 2 | 236
Schizophrenia 2 | 1,160
Strabismus 2 | 270
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
juvenile dermatomyositis 2 | 1,187
mucosa-associated lymphoid tissue lymphoma 2 | 484
nephrosclerosis 2 | 333
spina bifida 2 | 1,074

Tissue

Female tissues 48 | 17,400
Digestive Tract 47 | 17,369
Skin and soft tissues 47 | 17,230
Endocrine System 45 | 18,159
Blood and immune system 44 | 16,909
Liver and Pancreas 44 | 16,750
Male tissues 44 | 17,142
Respiratory system 44 | 16,393
Urinary Tract 44 | 16,678
Cardiovascular System 43 | 15,192
Nervous System 43 | 16,725

Target Family

Non-IDG 39 | 12,091
Enzyme 3 | 4,145
Transporter 3 | 473
Transcription Factor 2 | 1,400
Kinase 1 | 634

Compartment GO Term

AP-type membrane coat adaptor ... 48 | 48
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor-like 5 protein TCFL5 Tbio Transcription Factor -2.62447 404.7 161
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
AP-5 complex subunit sigma-1 AP5S1 Tdark Non-IDG 0.00000 4
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
Keratin, type I cuticular Ha7 KRT37 Tdark Non-IDG -1.63304 35.5 15
Calcium/calmodulin-dependent protein kinase type 1B PNCK Tbio Kinase -2.14753 82.1 161
AP-5 complex subunit zeta-1 AP5Z1 Tbio Transcription Factor -0.53740 2.90 61
Synergin gamma SYNRG Tdark Non-IDG -1.69335 48.2 24
Unconventional myosin-Ig MYO1G Tbio Non-IDG -1.98465 98.3 35
AP-5 complex subunit beta-1 AP5B1 Tdark Non-IDG -3.06187 1110.1 7