Development Level

Tbio 4 | 11,445

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal stomach morphology 1 | 10
decreased mean corpuscular vol... 1 | 79
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 36
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 4 | 8,520
Carcinoma 3 | 11,493
Abnormally small eyeball 2 | 97
Cancer 2 | 2,499
Coloboma of iris 2 | 38
Decreased size of eyeball 2 | 97
Microphthalmos 2 | 100
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
spina bifida 2 | 1,074
Accessory rib 1 | 10
Basal Cell Nevus Syndrome 1 | 5
Basal cell carcinoma 1 | 54
Basal cell nevi 1 | 23
Big calvaria 1 | 147
Brachydactyly 1 | 156
Brain Neoplasms 1 | 33
Breast Neoplasms 1 | 445
Calcification of falx cerebri 1 | 6
Carcinoma, Basal Cell 1 | 28
Carcinoma, squamous cell of head and neck 1 | 31
Cardiac fibroma 1 | 3
Cardiac rhabdomyoma 1 | 5
Cerebral calcification 1 | 43
Class III malocclusion 1 | 78
Cleft palate and bilateral cleft lip 1 | 4
Coarse facial features 1 | 108
Coloboma, Ocular, Autosomal Dominant 1 | 6
Congenital anomaly of neck 1 | 19
Congenital fusion of ribs 1 | 4
Congenital hemivertebra 1 | 25
Decreased mitochondrial complex I activity 1 | 2
Decreased mitochondrial complex III activity 1 | 2
Deformity of neck 1 | 19
Dyspnea 1 | 76
Friedreich ataxia 1 | 24
Frontal bossing 1 | 157
Fundus coloboma 1 | 18
Fused vertebrae 1 | 25
Gastrointestinal Stromal Tumors 1 | 48
Gorlin syndrome 1 | 4
Hamartomatous stomach polyps 1 | 3
Hematuria 1 | 36
Highly variable severity 1 | 157
Hypertrophy of lower jaw 1 | 78
Increased head circumference 1 | 147
Increased intramyocellular lipid droplets 1 | 13
Increased serum lactate 1 | 60
Increased size of cranium 1 | 147
Increased size of mandible 1 | 78
Increased size of skull 1 | 147
Irregular ossification of hand bones 1 | 3
Keratocystic Odontogenic Tumor 1 | 3
Kyphoscoliosis deformity of spine 1 | 60
Malformation of the neck 1 | 19
Mandibular hyperplasia 1 | 78
Melanocytic nevus 1 | 43
Meningioma, Familial, Susceptibility to 1 | 5
Meningioma, familial 1 | 6
Milium Cyst 1 | 16
Mitochondrial Myopathies 1 | 21
Motor delay 1 | 147
Muscle Cramp 1 | 55
Muscle Weakness 1 | 170
Neoplasm Metastasis 1 | 168
Nevoid basal cell carcinoma syndrome 1 | 16
No development of motor milestones 1 | 147
Noncancerous mole 1 | 28
Orbital cyst 1 | 8
Ovarian Fibromata 1 | 3
Ovarian Neoplasms 1 | 102
Palmar pit 1 | 4
Palpitations 1 | 18
Parietal bossing 1 | 5
Plantar pits 1 | 4
Respiratory complex I deficiency 1 | 2
Respiratory complex III deficiency 1 | 2
Sella Turcica, Bridged 1 | 3
Sensorineural Hearing Loss (disorder) 1 | 284
Short 4th metacarpal 1 | 7
Short ribs 1 | 30
Short thumb terminal phalanx 1 | 5
Sideroblastic anemia 1 | 20
Skin tag 1 | 14
Sloping shoulders 1 | 21
Spinal fusion 1 | 25
Sprengel deformity 1 | 16
Squamous cell carcinoma of the head and neck 1 | 29
Sternal anomalies 1 | 19
Thickened facial skin with coarse facial features 1 | 108
Variable expressivity 1 | 157
Vertebral body fusion 1 | 25
Vertebral wedging 1 | 4
Wilson-Turner syndrome 1 | 14
infantile cerebellar-retinal degeneration 1 | 3
interstitial lung disease 1 | 298
mandibular excess (physical finding) 1 | 78
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 4 | 12,091

Compartment GO Term

3-isopropylmalate dehydratase ... 4 | 4
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytosolic Fe-S cluster assembly factor NUBP1 NUBP1 Tbio Non-IDG -1.31867 20.0 105
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial ISCU Tbio Non-IDG -2.25839 167.3 167
Suppressor of fused homolog SUFU Tbio Non-IDG -2.33544 208.6 168
Transcriptional coactivator YAP1 YAP1 Tbio Non-IDG -2.62274 411.7 581