Development Level

Tchem 29 | 1,598
Tbio 5 | 11,445
Tdark 3 | 6,588

Collection

Kinase: IDG Consortium (Comple... 37 | 37
GPCR: IDG Consortium (Targets) 126 | 126
Kinase: IDG Consortium (Target... 125 | 125
Ion Channel: IDG Consortium (T... 99 | 99
GPCR: IDG Consortium (Complete... 25 | 25

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
edema 1 | 59
embryonic growth retardation 1 | 106
hypoactivity 1 | 132
increased circulating alkaline... 1 | 122
increased circulating iron lev... 1 | 30
increased leukocyte cell numbe... 1 | 47
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 31 | 11,493
osteosarcoma 21 | 7,950
medulloblastoma, large-cell 19 | 6,241
ovarian cancer 19 | 8,520
ependymoma 16 | 4,679
glioblastoma 14 | 5,792
atypical teratoid / rhabdoid tumor 13 | 5,112
psoriasis 13 | 6,694
Kidney cancer 12 | 2,613
adult high grade glioma 10 | 3,801
group 4 medulloblastoma 10 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
malignant mesothelioma 10 | 3,232
Astrocytoma, Pilocytic 9 | 3,081
Pick disease 9 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
lung cancer 9 | 4,740
primitive neuroectodermal tumor 9 | 3,035
Breast cancer 8 | 3,578
Rheumatoid arthritis 8 | 1,191
oligodendroglioma 8 | 2,850
subependymal giant cell astrocytoma 8 | 2,287
astrocytic glioma 7 | 2,597
interstitial cystitis 7 | 2,312
pancreatic cancer 7 | 2,398
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
non-small cell lung cancer 5 | 2,890
primary pancreatic ductal adenocarcinoma 5 | 1,109
aldosterone-producing adenoma 4 | 665
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
medulloblastoma 4 | 720
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
tuberculosis 4 | 2,010
Autosomal recessive predisposition 3 | 1,442
Ciliopathy 3 | 71
Intellectual disability 3 | 1,016
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
pediatric high grade glioma 3 | 1,064
progressive supranuclear palsy 3 | 676
Ambiguous Genitalia 2 | 24
Amyotrophic lateral sclerosis 2 | 451
Autistic Disorder 2 | 364
Autosomal dominant polycystic kidney disease 2 | 31
Autosomal recessive polycystic kidney disease 2 | 41
Chronic Lymphocytic Leukemia 2 | 262
Cleft Palate 2 | 271
Congenital hereditary endothelial dystrophy of cornea 2 | 8
Cystic kidney disease 2 | 26
Dilated ventricles (finding) 2 | 121
Gaucher disease type 1 2 | 180
Hamman-Rich syndrome 2 | 34
Hemolytic anemia 2 | 77
Liver cancer 2 | 604
Nephronophthisis 2 | 80
Prostate cancer 2 | 175
Pseudohypoaldosteronism 2 | 23
Uranostaphyloschisis 2 | 167
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
colon cancer 2 | 1,478
cystic fibrosis and chronic rhinosinusitis 2 | 214
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
hepatocellular carcinoma 2 | 547
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 416
tuberculosis and treatment for 6 months 2 | 409
ulcerative colitis 2 | 1,819
Abnormality of the fingernails 1 | 51
Acute myeloid leukemia, disease 1 | 30
Auricular malformation 1 | 41
Chromosome 17q11.2 deletion syndrome, 1.4Mb 1 | 15
Decreased projection of midface 1 | 105
Ellis-Van Creveld syndrome 1 | 19
Epileptic encephalopathy 1 | 26
Fine hair 1 | 42
Gastrointestinal Stromal Tumors 1 | 48
Hypotrophic midface 1 | 105
Malignant neoplasm of prostate 1 | 11
Midface retrusion 1 | 105
Myoclonus 1 | 74
Neurogenic bladder 1 | 16
Ovarian Neoplasms 1 | 102
Pitt-Hopkins syndrome 1 | 20
Poor eye contact 1 | 12
Premature ovarian failure 1 | 65
Progressive microcephaly 1 | 32
Short ribs 1 | 30
Simple ear 1 | 41
Small midface 1 | 105

Tissue

Endocrine System 37 | 18,159
Blood and immune system 36 | 16,909
Digestive Tract 36 | 17,369
Female tissues 36 | 17,400
Liver and Pancreas 35 | 16,750
Nervous System 35 | 16,725
Skin and soft tissues 35 | 17,230
Urinary Tract 35 | 16,678
Male tissues 34 | 17,142
Respiratory system 34 | 16,393
Cardiovascular System 32 | 15,192

Target Family

Kinase 36 | 634
Enzyme 1 | 4,145

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAP kinase-interacting serine/threonine-protein kinase 1 MKNK1 Tchem Kinase -1.71576 46.7 408
Serine/threonine-protein kinase TAO2 TAOK2 Tchem Kinase -1.52454 36.1 154
Testis-specific serine/threonine-protein kinase 2 TSSK2 Tchem Kinase -1.03725 12.0 54
Mitogen-activated protein kinase kinase kinase 21 MAP3K21 Tdark Kinase -0.42420 4.24 174
Serine/threonine-protein kinase BRSK2 BRSK2 Tchem Kinase -1.92813 85.3 187
Serine/threonine-protein kinase LMTK2 LMTK2 Tbio Kinase -1.46351 31.6 189
Serine/threonine-protein kinase WNK3 WNK3 Tchem Kinase -1.14290 17.3 193
Cyclin-dependent kinase 12 CDK12 Tchem Kinase -1.38476 29.4 157
Mitogen-activated protein kinase kinase kinase 15 MAP3K15 Tchem Kinase -0.94156 6.81 97
Calcium/calmodulin-dependent protein kinase kinase 2 CAMKK2 Tchem Kinase -2.09841 125.5 257