Development Level

Tbio 63 | 10,625
Tdark 48 | 7,003
Tchem 27 | 1,890
Tclin 5 | 602

Collection

Eligible non-olfactory GPCR Proteins 143 | 143
Eligible Kinase Proteins 134 | 134
Eligible Ion Channel Proteins 117 | 117

IMPC Term

decreased bone mineral density 4 | 126
hyperactivity 3 | 108
abnormal behavior 2 | 226
abnormal gait 2 | 51
abnormal skin coloration 2 | 18
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased total body fat amoun... 2 | 186
improved glucose tolerance 2 | 56
increased exploration in new e... 2 | 56
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
absent pinna reflex 1 | 21
decreased circulating HDL chol... 1 | 77
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
enlarged epididymis 1 | 27
enlarged heart 1 | 111
female infertility 1 | 34
impaired glucose tolerance 1 | 52
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 32
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased red blood cell distr... 1 | 21
preweaning lethality, complete... 1 | 633
short tibia 1 | 82

Disease

psoriasis 40 | 6,685
medulloblastoma, large-cell 29 | 6,234
osteosarcoma 28 | 7,933
glioblastoma 20 | 5,572
atypical teratoid / rhabdoid tumor 19 | 4,369
lung carcinoma 19 | 2,844
ovarian cancer 19 | 8,484
interstitial cystitis 17 | 2,299
Breast cancer 16 | 3,094
lung cancer 15 | 4,466
lung adenocarcinoma 14 | 2,713
Carcinoma 12 | 2,147
adult high grade glioma 12 | 2,148
diabetes mellitus 12 | 1,663
malignant mesothelioma 12 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
oligodendroglioma 11 | 2,849
pituitary cancer 11 | 1,972
primitive neuroectodermal tumor 11 | 3,031
breast carcinoma 10 | 1,614
ductal carcinoma in situ 10 | 1,745
ependymoma 10 | 2,514
medulloblastoma 10 | 1,524
non-small cell lung cancer 10 | 2,798
invasive ductal carcinoma 9 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
pilocytic astrocytoma 8 | 3,086
posterior fossa group A ependymoma 8 | 1,511
ulcerative colitis 8 | 2,087
Schizophrenia 7 | 501
astrocytic glioma 7 | 2,241
esophageal adenocarcinoma 7 | 737
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
pediatric high grade glioma 7 | 2,712
group 4 medulloblastoma 6 | 1,875
pancreatic cancer 6 | 2,300
Pelvic inflammatory disease 5 | 21
astrocytoma 5 | 1,493
colon cancer 5 | 1,475
cutaneous lupus erythematosus 5 | 1,056
cystic fibrosis 5 | 1,665
mucosa-associated lymphoid tissue lymphoma 5 | 480
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
subependymal giant cell astrocytoma 5 | 2,287
Atopic dermatitis 4 | 944
Obesity 4 | 616
adrenocortical carcinoma 4 | 1,427
atypical teratoid/rhabdoid tumor 4 | 1,095
gastric carcinoma 4 | 832
non-small cell lung carcinoma 4 | 413
primary Sjogren syndrome 4 | 789
spina bifida 4 | 1,064
tuberculosis 4 | 1,557
Duchenne muscular dystrophy 3 | 602
Multiple Sclerosis 3 | 498
juvenile dermatomyositis 3 | 1,189
nasopharyngeal carcinoma 3 | 1,056
posterior fossa group B ependymoma 3 | 1,530
sonic hedgehog group medulloblastoma 3 | 1,482
tuberculosis and treatment for 3 months 3 | 327
Acromegaly 2 | 40
Adenoma 2 | 165
Alcoholic Intoxication, Chronic 2 | 41
Attention deficit hyperactivity disorder 2 | 156
Autistic Disorder 2 | 320
Cardiovascular system disease 2 | 194
Cocaine-Related Disorders 2 | 88
Cognitive disorder 2 | 44
Epilepsy 2 | 346
Major Depressive Disorder 2 | 106
Migraine 2 | 79
Substance Withdrawal Syndrome 2 | 52
Urticaria 2 | 53
active Crohn's disease 2 | 918
active ulcerative colitis 2 | 477
acute myeloid leukemia 2 | 780
acute quadriplegic myopathy 2 | 1,157
aldosterone-producing adenoma 2 | 664
chronic rhinosinusitis 2 | 512
facioscapulohumeral dystrophy 2 | 286
glioblastoma multiforme 2 | 347
group 3 medulloblastoma 2 | 2,254
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
non primary Sjogren syndrome sicca 2 | 840
non-inflammatory breast cancer 2 | 208
sarcoidosis 2 | 358
Asperger syndrome 1 | 35
Asthma management 1 | 20
Cone dystrophy 1 | 57
Gilles de la Tourette syndrome 1 | 47
Metabolic acidosis 1 | 49
Mitral valve insufficiency 1 | 17
Nasal polyp 1 | 2
Nicotine dependence 1 | 53
Primary immunodeficiency disease 1 | 52
Rectal neoplasm 1 | 7
Rhinitis 1 | 46
Vasomotor rhinitis 1 | 15
axial spondyloarthropathy 1 | 28
obsessive-compulsive disorder 1 | 34

Tissue

Nervous System 130 | 18,561
Female tissues 129 | 18,647
Urinary Tract 127 | 18,444
Endocrine System 126 | 18,512
Digestive Tract 123 | 18,473
Skin and soft tissues 120 | 18,115
Cardiovascular System 115 | 17,958
Liver and Pancreas 114 | 18,136
Blood and immune system 108 | 17,995
Male tissues 106 | 17,969
Respiratory system 104 | 17,484

Target Family

GPCR 143 | 406

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuropeptides B/W receptor type 1 NPBWR1 Tchem GPCR -1.34565 19.5 151
Neuropeptides B/W receptor type 2 NPBWR2 Tbio GPCR -1.14202 8.84 57
G-protein coupled receptor 26 GPR26 Tbio GPCR -0.57545 4.04 88
Probable G-protein coupled receptor 150 GPR150 Tdark GPCR 0.32 0.42 116
G-protein coupled receptor 42 GPR42 Tdark GPCR 0.30 0.38 4
G-protein coupled receptor 4 GPR4 Tchem GPCR -1.57104 43.8 104
G-protein coupled receptor 6 GPR6 Tchem GPCR -1.01435 10.3 60
Probable G-protein coupled receptor 139 GPR139 Tchem GPCR -1.13244 14.2 92
Adhesion G protein-coupled receptor F5 ADGRF5 Tbio GPCR -0.84160 8.64 151
Adhesion G protein-coupled receptor F4 ADGRF4 Tdark GPCR -0.30222 1.74 150