Development Level

Tbio 170 | 11,651
Tchem 31 | 1,388
Tclin 21 | 612
Tdark 20 | 6,593

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, incomple... 10 | 499
abnormal behavior 9 | 298
preweaning lethality, complete... 9 | 979
abnormal sleep behavior 4 | 70
decreased total body fat amoun... 4 | 207
abnormal bone structure 3 | 187
abnormal coat appearance 3 | 31
abnormal embryo size 3 | 220
abnormal eye morphology 3 | 68
decreased body length 3 | 101
decreased circulating glucose ... 3 | 126
decreased grip strength 3 | 116
decreased vertical activity 3 | 208
impaired glucose tolerance 3 | 75
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
increased heart weight 3 | 62
abnormal limb bud morphology 2 | 17
abnormal limb position 2 | 3
abnormal seminal vesicle morph... 2 | 114
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased exploration in new e... 2 | 11
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular hem... 2 | 31
decreased startle reflex 2 | 75
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hypoactivity 2 | 132
increased circulating glycerol... 2 | 9
increased circulating thyroxin... 2 | 7
increased circulating triglyce... 2 | 42
increased erythrocyte cell num... 2 | 39
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
pallor 2 | 34
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal response to new envir... 1 | 10
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hemorrhage 1 | 23
hyperactivity 1 | 148
increased aggression 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
male infertility 1 | 123
pale yolk sac 1 | 25
premature death 1 | 5
prolonged RR interval 1 | 8
short tibia 1 | 97
trunk curl 1 | 16
unresponsive to tactile stimul... 1 | 8
vertebral fusion 1 | 23

Disease

Carcinoma 191 | 11,493
ovarian cancer 163 | 8,520
osteosarcoma 138 | 7,950
glioblastoma 135 | 5,792
medulloblastoma, large-cell 119 | 6,241
atypical teratoid / rhabdoid tumor 108 | 5,112
psoriasis 108 | 6,694
ependymoma 105 | 4,679
lung cancer 103 | 4,740
Breast cancer 93 | 3,578
Cancer 93 | 2,499
malignant mesothelioma 89 | 3,232
lung carcinoma 88 | 2,843
non-small cell lung cancer 81 | 2,890
Astrocytoma, Pilocytic 79 | 3,081
adult high grade glioma 76 | 3,801
invasive ductal carcinoma 76 | 2,951
pancreatic cancer 76 | 2,398
group 3 medulloblastoma 73 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 71 | 3,291
oligodendroglioma 71 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 69 | 2,955
lung adenocarcinoma 67 | 2,716
Kidney cancer 66 | 2,613
ulcerative colitis 65 | 1,819
interstitial cystitis 64 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 63 | 2,989
cystic fibrosis 60 | 1,696
astrocytic glioma 59 | 2,597
primitive neuroectodermal tumor 56 | 3,035
pancreatic ductal adenocarcinoma liver metastasis 53 | 1,962
subependymal giant cell astrocytoma 52 | 2,287
primary pancreatic ductal adenocarcinoma 51 | 1,109
diabetes mellitus 47 | 1,728
pituitary cancer 44 | 1,972
tuberculosis 44 | 2,010
juvenile dermatomyositis 43 | 1,187
ductal carcinoma in situ 41 | 1,745
group 4 medulloblastoma 41 | 1,855
acute quadriplegic myopathy 40 | 1,158
breast carcinoma 40 | 1,638
colon cancer 39 | 1,478
gastric carcinoma 39 | 807
Duchenne muscular dystrophy 35 | 601
Pick disease 35 | 1,894
adrenocortical carcinoma 33 | 1,428
Autosomal recessive predisposition 31 | 1,442
Alzheimer's disease 30 | 658
pediatric high grade glioma 30 | 1,064
autosomal dominant Emery-Dreifuss muscular dystrophy 29 | 510
Rheumatoid arthritis 28 | 1,191
Schizophrenia 28 | 1,160
dermatomyositis 28 | 966
esophageal adenocarcinoma 28 | 737
astrocytoma 27 | 1,146
Liver Cirrhosis, Experimental 26 | 769
Multiple myeloma 26 | 1,332
Down syndrome 23 | 499
Multiple Sclerosis 23 | 540
nasopharyngeal carcinoma 23 | 1,058
aldosterone-producing adenoma 22 | 665
Breast Neoplasms 21 | 445
cutaneous lupus erythematosus 21 | 1,057
Atopic dermatitis 20 | 952
Endometriosis 20 | 540
Mammary Neoplasms 20 | 425
Melanoma 19 | 711
Vascular disease 19 | 319
mucosa-associated lymphoid tissue lymphoma 19 | 484
Liver cancer 18 | 604
Prostatic Neoplasms 18 | 495
active Crohn's disease 18 | 922
primary Sjogren syndrome 18 | 735
Atherosclerosis 17 | 291
Hypersensitivity reaction type II disease 17 | 253
Kidney disease 17 | 430
medulloblastoma 17 | 720
spina bifida 17 | 1,074
acute myeloid leukemia 16 | 783
Liver carcinoma 15 | 240
Neoplasm Invasiveness 15 | 161
fibroadenoma 15 | 559
Anemia 14 | 365
Carcinoma, Hepatocellular 14 | 228
Stomach Neoplasms 14 | 300
active ulcerative colitis 14 | 764
interstitial lung disease 14 | 298
posterior fossa group A ependymoma 14 | 468
sonic hedgehog group medulloblastoma 14 | 467
Barrett's esophagus 13 | 182
Coronary artery disease 13 | 268
Hypertension 13 | 396
Intellectual disability 13 | 1,016
Liver disease 13 | 237
Skin cancer 13 | 469
Waldenstrons macroglobulinemia 13 | 765
progressive supranuclear palsy 13 | 676
Arthritis 12 | 290
Cerebrovascular disease 12 | 238
Myocardial Ischemia 12 | 169

Tissue

Endocrine System 235 | 18,159
Female tissues 235 | 17,400
Male tissues 235 | 17,142
Nervous System 235 | 16,725
Respiratory system 235 | 16,393
Skin and soft tissues 235 | 17,230
Blood and immune system 234 | 16,909
Digestive Tract 234 | 17,369
Liver and Pancreas 234 | 16,750
Urinary Tract 234 | 16,678
Cardiovascular System 231 | 15,192

Target Family

Non-IDG 165 | 12,091
Enzyme 38 | 4,145
Transporter 15 | 473
Kinase 13 | 634
GPCR 7 | 408
Ion Channel 3 | 344
Transcription Factor 1 | 1,400

CSPA Cell Line

U-87 MG 242 | 242
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
Protein phosphatase 1 regulatory subunit 29 ELFN2 Tdark Enzyme 0.06 0.68 51
Protein tweety homolog 3 TTYH3 Tbio Ion Channel -0.17609 1.56 17
Interleukin-6 receptor subunit beta IL6ST Tclin Non-IDG -1.72489 55.4 555
Integrin alpha-9 ITGA9 Tbio Non-IDG -1.46619 29.0 124
Integrin beta-8 ITGB8 Tbio Non-IDG -1.47947 27.7 99
Integrin alpha-3 ITGA3 Tbio Non-IDG -2.08360 104.1 587
Interferon gamma receptor 1 IFNGR1 Tbio Non-IDG -2.23009 172.7 518
CD166 antigen ALCAM Tbio Non-IDG -2.49297 326.4 492