Development Level

Tbio 199 | 11,445
Tchem 35 | 1,598
Tdark 28 | 6,588
Tclin 24 | 613

Collection

RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Complete... 2 | 25
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal behavior 13 | 298
preweaning lethality, incomple... 13 | 499
preweaning lethality, complete... 12 | 979
enlarged heart 9 | 210
decreased vertical activity 6 | 208
abnormal seminal vesicle morph... 5 | 114
decreased grip strength 5 | 116
decreased total body fat amoun... 5 | 207
abnormal bone structure 4 | 187
abnormal heart morphology 4 | 162
hyperactivity 4 | 148
increased bone mineral content 4 | 108
increased heart weight 4 | 62
increased lean body mass 4 | 172
abnormal coat appearance 3 | 31
abnormal eye morphology 3 | 68
decreased body length 3 | 101
decreased body weight 3 | 161
decreased circulating glucose ... 3 | 126
decreased circulating triglyce... 3 | 79
enlarged spleen 3 | 41
hypoactivity 3 | 132
impaired glucose tolerance 3 | 75
improved glucose tolerance 3 | 79
increased mean corpuscular vol... 3 | 92
increased total body fat amoun... 3 | 134
male infertility 3 | 123
tremors 3 | 39
abnormal bone mineralization 2 | 38
abnormal embryo size 2 | 220
abnormal kidney morphology 2 | 65
abnormal limb bud morphology 2 | 17
abnormal pericardium morpholog... 2 | 26
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
cardiovascular system phenotyp... 2 | 36
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased cardiac muscle contr... 2 | 11
decreased circulating creatini... 2 | 39
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased heart rate 2 | 18
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 31
decreased startle reflex 2 | 75
embryonic lethality prior to t... 2 | 278
increased B cell number 2 | 9
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased erythrocyte cell num... 2 | 39
pallor 2 | 34
abnormal behavioral response t... 1 | 66
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal liver morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal tail movements 1 | 12
abnormal vibrissa morphology 1 | 25
abnormal vitelline vasculature... 1 | 6
abnormal vocalization 1 | 21
absent vibrissae 1 | 12
decreased T cell number 1 | 15
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased mean platelet volume 1 | 25
decreased total retina thickne... 1 | 17
dilated heart left ventricle 1 | 11
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
increased aggression 1 | 4
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased exploration in new e... 1 | 8
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
increased vertical activity 1 | 24
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
premature death 1 | 5
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 221 | 11,493
ovarian cancer 194 | 8,520
glioblastoma 170 | 5,792
osteosarcoma 155 | 7,950
medulloblastoma, large-cell 135 | 6,241
psoriasis 135 | 6,694
ependymoma 132 | 4,679
atypical teratoid / rhabdoid tumor 124 | 5,112
Breast cancer 109 | 3,578
malignant mesothelioma 108 | 3,232
Astrocytoma, Pilocytic 105 | 3,081
lung cancer 100 | 4,740
Cancer 97 | 2,499
adult high grade glioma 96 | 3,801
group 3 medulloblastoma 95 | 4,104
invasive ductal carcinoma 94 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 93 | 2,955
pancreatic cancer 92 | 2,398
lung carcinoma 90 | 2,843
non-small cell lung cancer 82 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 81 | 3,291
lung adenocarcinoma 79 | 2,716
oligodendroglioma 79 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 78 | 2,989
Kidney cancer 74 | 2,613
ulcerative colitis 74 | 1,819
primitive neuroectodermal tumor 72 | 3,035
subependymal giant cell astrocytoma 68 | 2,287
cystic fibrosis 67 | 1,696
astrocytic glioma 66 | 2,597
primary pancreatic ductal adenocarcinoma 64 | 1,109
interstitial cystitis 62 | 2,312
pituitary cancer 56 | 1,972
diabetes mellitus 54 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 54 | 1,962
tuberculosis 54 | 2,010
breast carcinoma 53 | 1,638
juvenile dermatomyositis 52 | 1,187
ductal carcinoma in situ 51 | 1,745
gastric carcinoma 51 | 807
group 4 medulloblastoma 47 | 1,855
Autosomal recessive predisposition 46 | 1,442
Duchenne muscular dystrophy 45 | 601
Pick disease 43 | 1,894
dermatomyositis 40 | 966
pediatric high grade glioma 40 | 1,064
adrenocortical carcinoma 39 | 1,428
colon cancer 39 | 1,478
acute quadriplegic myopathy 37 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 37 | 510
astrocytoma 36 | 1,146
Liver Cirrhosis, Experimental 35 | 769
Schizophrenia 34 | 1,160
Rheumatoid arthritis 30 | 1,191
esophageal adenocarcinoma 29 | 737
Alzheimer's disease 28 | 658
Multiple Sclerosis 28 | 540
nasopharyngeal carcinoma 28 | 1,058
Multiple myeloma 27 | 1,332
Atopic dermatitis 26 | 952
cutaneous lupus erythematosus 24 | 1,057
Liver cancer 23 | 604
Melanoma 23 | 711
fibroadenoma 23 | 559
Down syndrome 22 | 499
Kidney disease 22 | 430
active Crohn's disease 22 | 922
active ulcerative colitis 22 | 764
Vascular disease 21 | 319
mucosa-associated lymphoid tissue lymphoma 21 | 484
interstitial lung disease 20 | 298
primary Sjogren syndrome 20 | 735
Hypersensitivity reaction type II disease 19 | 253
Becker muscular dystrophy 18 | 191
aldosterone-producing adenoma 18 | 665
medulloblastoma 18 | 720
Acquired scoliosis 17 | 281
Atherosclerosis 17 | 291
Breast Neoplasms 17 | 445
Curvature of spine 17 | 282
Intellectual disability 17 | 1,016
Liver Cirrhosis 17 | 181
Prostatic Neoplasms 17 | 495
spina bifida 17 | 1,074
Endometriosis 16 | 540
Mammary Neoplasms 16 | 425
Muscle hypotonia 16 | 571
Neoplasm Invasiveness 16 | 161
Obesity 16 | 678
Short stature 16 | 531
limb girdle muscular dystrophy 2A 16 | 213
progressive supranuclear palsy 16 | 676
Arthritis 15 | 290
Asthma 15 | 385
Coronary artery disease 15 | 268
Skin cancer 15 | 469
sonic hedgehog group medulloblastoma 15 | 467
urothelial carcinoma 15 | 318
Low intelligence 14 | 645
Mental Retardation 14 | 645

Tissue

Endocrine System 279 | 18,159
Urinary Tract 279 | 16,678
Digestive Tract 278 | 17,369
Female tissues 278 | 17,400
Liver and Pancreas 278 | 16,750
Male tissues 278 | 17,142
Skin and soft tissues 278 | 17,230
Blood and immune system 277 | 16,909
Respiratory system 277 | 16,393
Nervous System 276 | 16,725
Cardiovascular System 274 | 15,192

Target Family

Non-IDG 206 | 12,091
Enzyme 37 | 4,145
GPCR 14 | 408
Transporter 14 | 473
Kinase 9 | 634
Ion Channel 5 | 344
Transcription Factor 1 | 1,400

CSPA Cell Line

U-2 OS 286 | 286
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier organic anion transporter family member 3A1 SLCO3A1 Tbio Transporter -1.39614 24.1 46
Proteinase-activated receptor 1 F2R Tclin GPCR -2.78393 551.0 453
Endothelial protein C receptor PROCR Tbio Non-IDG -2.70271 541.0 367
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Epsilon-sarcoglycan SGCE Tbio Non-IDG -2.19042 158.3 93
Collagen alpha-2(V) chain COL5A2 Tbio Non-IDG -1.69982 44.6 96
Discoidin, CUB and LCCL domain-containing protein 2 DCBLD2 Tbio Non-IDG -1.08601 14.5 196
Cadherin EGF LAG seven-pass G-type receptor 2 CELSR2 Tbio GPCR -1.22995 16.7 139
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.23182 177.1 76
Ephrin type-B receptor 3 EPHB3 Tchem Kinase -1.68968 47.7 409