Development Level

Tbio 186 | 11,445
Tchem 36 | 1,598
Tclin 32 | 613
Tdark 22 | 6,588

Collection

GPCR: IDG Consortium (Complete... 3 | 25
RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 12 | 979
abnormal behavior 9 | 298
preweaning lethality, incomple... 9 | 499
abnormal embryo size 6 | 220
decreased total body fat amoun... 6 | 207
embryonic lethality prior to t... 5 | 278
abnormal bone structure 4 | 187
decreased grip strength 4 | 116
decreased vertical activity 4 | 208
increased bone mineral content 4 | 108
increased lean body mass 4 | 172
increased total body fat amoun... 4 | 134
abnormal eye morphology 3 | 68
abnormal limb bud morphology 3 | 17
abnormal seminal vesicle morph... 3 | 114
decreased body length 3 | 101
decreased circulating glucose ... 3 | 126
embryonic growth retardation 3 | 106
enlarged heart 3 | 210
increased erythrocyte cell num... 3 | 39
increased heart weight 3 | 62
abnormal coat appearance 2 | 31
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 31
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
enlarged spleen 2 | 41
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased circulating choleste... 2 | 66
increased circulating glycerol... 2 | 9
increased circulating triglyce... 2 | 42
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
male infertility 2 | 123
pallor 2 | 34
prolonged ST segment 2 | 36
tremors 2 | 39
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean platelet volume 1 | 25
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hypoactivity 1 | 132
increased aggression 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased vertical activity 1 | 24
microphthalmia 1 | 26
premature death 1 | 5
syndactyly 1 | 23
trunk curl 1 | 16
unresponsive to tactile stimul... 1 | 8
vertebral fusion 1 | 23

Disease

Carcinoma 222 | 11,493
ovarian cancer 184 | 8,520
glioblastoma 153 | 5,792
osteosarcoma 149 | 7,950
medulloblastoma, large-cell 134 | 6,241
psoriasis 127 | 6,694
atypical teratoid / rhabdoid tumor 125 | 5,112
ependymoma 120 | 4,679
Cancer 113 | 2,499
malignant mesothelioma 113 | 3,232
Breast cancer 108 | 3,578
lung cancer 107 | 4,740
lung carcinoma 104 | 2,843
Astrocytoma, Pilocytic 98 | 3,081
invasive ductal carcinoma 93 | 2,951
pancreatic cancer 93 | 2,398
non-small cell lung cancer 90 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 83 | 2,955
group 3 medulloblastoma 81 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 81 | 3,291
ulcerative colitis 81 | 1,819
adult high grade glioma 80 | 3,801
lung adenocarcinoma 79 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 77 | 2,989
Kidney cancer 75 | 2,613
interstitial cystitis 75 | 2,312
oligodendroglioma 70 | 2,850
subependymal giant cell astrocytoma 69 | 2,287
cystic fibrosis 66 | 1,696
primary pancreatic ductal adenocarcinoma 63 | 1,109
primitive neuroectodermal tumor 59 | 3,035
astrocytic glioma 58 | 2,597
ductal carcinoma in situ 55 | 1,745
pituitary cancer 55 | 1,972
juvenile dermatomyositis 53 | 1,187
tuberculosis 53 | 2,010
diabetes mellitus 51 | 1,728
breast carcinoma 50 | 1,638
gastric carcinoma 50 | 807
pancreatic ductal adenocarcinoma liver metastasis 49 | 1,962
Duchenne muscular dystrophy 47 | 601
colon cancer 45 | 1,478
adrenocortical carcinoma 43 | 1,428
group 4 medulloblastoma 42 | 1,855
Pick disease 41 | 1,894
Autosomal recessive predisposition 40 | 1,442
astrocytoma 40 | 1,146
acute quadriplegic myopathy 39 | 1,158
dermatomyositis 38 | 966
cutaneous lupus erythematosus 35 | 1,057
esophageal adenocarcinoma 35 | 737
pediatric high grade glioma 35 | 1,064
Schizophrenia 34 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 34 | 510
Rheumatoid arthritis 33 | 1,191
active Crohn's disease 30 | 922
nasopharyngeal carcinoma 30 | 1,058
Alzheimer's disease 29 | 658
Multiple myeloma 29 | 1,332
Liver Cirrhosis, Experimental 28 | 769
Multiple Sclerosis 27 | 540
fibroadenoma 25 | 559
Atopic dermatitis 24 | 952
Breast Neoplasms 24 | 445
primary Sjogren syndrome 24 | 735
Liver cancer 23 | 604
Mammary Neoplasms 23 | 425
Down syndrome 22 | 499
Melanoma 22 | 711
Endometriosis 21 | 540
Prostatic Neoplasms 21 | 495
active ulcerative colitis 21 | 764
aldosterone-producing adenoma 21 | 665
Kidney disease 19 | 430
spina bifida 19 | 1,074
Arthritis 18 | 290
Hypersensitivity reaction type II disease 18 | 253
Vascular disease 18 | 319
mucosa-associated lymphoid tissue lymphoma 18 | 484
posterior fossa group A ependymoma 18 | 468
sonic hedgehog group medulloblastoma 18 | 467
Anemia 17 | 365
Asthma 17 | 385
Short stature 17 | 531
acute myeloid leukemia 17 | 783
medulloblastoma 17 | 720
Becker muscular dystrophy 16 | 191
Intellectual disability 16 | 1,016
Lung Neoplasms 16 | 232
Neoplasm Invasiveness 16 | 161
Skin cancer 16 | 469
Stomach Neoplasms 16 | 300
Acquired scoliosis 15 | 281
Atherosclerosis 15 | 291
Curvature of spine 15 | 282
Epilepsy 15 | 792
Hypertensive disease 15 | 292
Liver carcinoma 15 | 240
Waldenstrons macroglobulinemia 15 | 765
non primary Sjogren syndrome sicca 15 | 891

Tissue

Endocrine System 270 | 18,159
Digestive Tract 269 | 17,369
Female tissues 269 | 17,400
Male tissues 269 | 17,142
Respiratory system 269 | 16,393
Urinary Tract 269 | 16,678
Blood and immune system 268 | 16,909
Liver and Pancreas 268 | 16,750
Nervous System 268 | 16,725
Skin and soft tissues 267 | 17,230
Cardiovascular System 264 | 15,192

Target Family

Non-IDG 189 | 12,091
Enzyme 36 | 4,145
Kinase 16 | 634
Transporter 14 | 473
GPCR 13 | 408
Ion Channel 6 | 344
Transcription Factor 2 | 1,400

CSPA Cell Line

T98G 276 | 276
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier organic anion transporter family member 3A1 SLCO3A1 Tbio Transporter -1.39614 24.1 46
Carbonic anhydrase 12 CA12 Tclin Enzyme -2.28368 173.2 309
Proteinase-activated receptor 1 F2R Tclin GPCR -2.78393 551.0 453
Endothelial protein C receptor PROCR Tbio Non-IDG -2.70271 541.0 367
Epsilon-sarcoglycan SGCE Tbio Non-IDG -2.19042 158.3 93
Discoidin, CUB and LCCL domain-containing protein 2 DCBLD2 Tbio Non-IDG -1.08601 14.5 196
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.23182 177.1 76
Ephrin type-B receptor 4 EPHB4 Tchem Kinase -2.26622 206.3 514
Plexin-D1 PLXND1 Tbio Non-IDG -1.64721 46.3 171
Leukemia inhibitory factor receptor LIFR Tbio Non-IDG -2.35146 221.3 249