Development Level

Tbio 186 | 11,445
Tchem 36 | 1,598
Tclin 32 | 613
Tdark 22 | 6,588

Collection

GPCR: IDG Consortium (Complete... 3 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 12 | 979
abnormal behavior 9 | 298
preweaning lethality, incomple... 9 | 499
abnormal embryo size 6 | 220
decreased total body fat amoun... 6 | 207
embryonic lethality prior to t... 5 | 278
abnormal bone structure 4 | 187
decreased grip strength 4 | 116
decreased vertical activity 4 | 208
increased bone mineral content 4 | 108
increased lean body mass 4 | 172
increased total body fat amoun... 4 | 134
abnormal eye morphology 3 | 68
abnormal limb bud morphology 3 | 17
abnormal seminal vesicle morph... 3 | 114
decreased body length 3 | 101
decreased circulating glucose ... 3 | 126
embryonic growth retardation 3 | 106
enlarged heart 3 | 210
increased erythrocyte cell num... 3 | 39
increased heart weight 3 | 62
abnormal coat appearance 2 | 31
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 31
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
enlarged spleen 2 | 41
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased circulating choleste... 2 | 66
increased circulating glycerol... 2 | 9
increased circulating triglyce... 2 | 42
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
male infertility 2 | 123
pallor 2 | 34
prolonged ST segment 2 | 36
tremors 2 | 39
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean platelet volume 1 | 25
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hypoactivity 1 | 132
increased aggression 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased vertical activity 1 | 24
microphthalmia 1 | 26
premature death 1 | 5
syndactyly 1 | 23
trunk curl 1 | 16
unresponsive to tactile stimul... 1 | 8
vertebral fusion 1 | 23

Disease

Carcinoma 222 | 11,493
ovarian cancer 184 | 8,520
glioblastoma 153 | 5,792
osteosarcoma 149 | 7,950
medulloblastoma, large-cell 134 | 6,241
psoriasis 127 | 6,694
atypical teratoid / rhabdoid tumor 125 | 5,112
ependymoma 120 | 4,679
Cancer 113 | 2,499
malignant mesothelioma 113 | 3,232
Breast cancer 108 | 3,578
lung cancer 107 | 4,740
lung carcinoma 104 | 2,843
Astrocytoma, Pilocytic 98 | 3,081
invasive ductal carcinoma 93 | 2,951
pancreatic cancer 93 | 2,398
non-small cell lung cancer 90 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 83 | 2,955
group 3 medulloblastoma 81 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 81 | 3,291
ulcerative colitis 81 | 1,819
adult high grade glioma 80 | 3,801
lung adenocarcinoma 79 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 77 | 2,989
Kidney cancer 75 | 2,613
interstitial cystitis 75 | 2,312
oligodendroglioma 70 | 2,850
subependymal giant cell astrocytoma 69 | 2,287
cystic fibrosis 66 | 1,696
primary pancreatic ductal adenocarcinoma 63 | 1,109
primitive neuroectodermal tumor 59 | 3,035
astrocytic glioma 58 | 2,597
ductal carcinoma in situ 55 | 1,745
pituitary cancer 55 | 1,972
juvenile dermatomyositis 53 | 1,187
tuberculosis 53 | 2,010
diabetes mellitus 51 | 1,728
breast carcinoma 50 | 1,638
gastric carcinoma 50 | 807
pancreatic ductal adenocarcinoma liver metastasis 49 | 1,962
Duchenne muscular dystrophy 47 | 601
colon cancer 45 | 1,478
adrenocortical carcinoma 43 | 1,428
group 4 medulloblastoma 42 | 1,855
Pick disease 41 | 1,894
Autosomal recessive predisposition 40 | 1,442
astrocytoma 40 | 1,146
acute quadriplegic myopathy 39 | 1,158
dermatomyositis 38 | 966
cutaneous lupus erythematosus 35 | 1,057
esophageal adenocarcinoma 35 | 737
pediatric high grade glioma 35 | 1,064
Schizophrenia 34 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 34 | 510
Rheumatoid arthritis 33 | 1,191
active Crohn's disease 30 | 922
nasopharyngeal carcinoma 30 | 1,058
Alzheimer's disease 29 | 658
Multiple myeloma 29 | 1,332
Liver Cirrhosis, Experimental 28 | 769
Multiple Sclerosis 27 | 540
fibroadenoma 25 | 559
Atopic dermatitis 24 | 952
Breast Neoplasms 24 | 445
primary Sjogren syndrome 24 | 735
Liver cancer 23 | 604
Mammary Neoplasms 23 | 425
Down syndrome 22 | 499
Melanoma 22 | 711
Endometriosis 21 | 540
Prostatic Neoplasms 21 | 495
active ulcerative colitis 21 | 764
aldosterone-producing adenoma 21 | 665
Kidney disease 19 | 430
spina bifida 19 | 1,074
Arthritis 18 | 290
Hypersensitivity reaction type II disease 18 | 253
Vascular disease 18 | 319
mucosa-associated lymphoid tissue lymphoma 18 | 484
posterior fossa group A ependymoma 18 | 468
sonic hedgehog group medulloblastoma 18 | 467
Anemia 17 | 365
Asthma 17 | 385
Short stature 17 | 531
acute myeloid leukemia 17 | 783
medulloblastoma 17 | 720
Becker muscular dystrophy 16 | 191
Intellectual disability 16 | 1,016
Lung Neoplasms 16 | 232
Neoplasm Invasiveness 16 | 161
Skin cancer 16 | 469
Stomach Neoplasms 16 | 300
Acquired scoliosis 15 | 281
Atherosclerosis 15 | 291
Curvature of spine 15 | 282
Epilepsy 15 | 792
Hypertensive disease 15 | 292
Liver carcinoma 15 | 240
Waldenstrons macroglobulinemia 15 | 765
non primary Sjogren syndrome sicca 15 | 891

Tissue

Endocrine System 270 | 18,159
Digestive Tract 269 | 17,369
Female tissues 269 | 17,400
Male tissues 269 | 17,142
Respiratory system 269 | 16,393
Urinary Tract 269 | 16,678
Blood and immune system 268 | 16,909
Liver and Pancreas 268 | 16,750
Nervous System 268 | 16,725
Skin and soft tissues 267 | 17,230
Cardiovascular System 264 | 15,192

Target Family

Non-IDG 189 | 12,091
Enzyme 36 | 4,145
Kinase 16 | 634
Transporter 14 | 473
GPCR 13 | 408
Ion Channel 6 | 344
Transcription Factor 2 | 1,400

CSPA Cell Line

T98G 276 | 276
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.11308 129.3 11
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Cadherin-10 CDH10 Tbio Non-IDG -0.86821 9.34 155
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Protocadherin gamma-A9 PCDHGA9 Tdark Non-IDG 0.51 0.72 31
Trophoblast glycoprotein TPBG Tbio Non-IDG -2.10560 136.9 206