Development Level

Tbio 101 | 11,445
Tclin 23 | 613
Tchem 22 | 1,598
Tdark 8 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, incomple... 11 | 499
abnormal behavior 7 | 298
decreased total body fat amoun... 5 | 207
decreased vertical activity 4 | 208
hyperactivity 4 | 148
increased bone mineral content 4 | 108
abnormal bone structure 3 | 187
abnormal seminal vesicle morph... 3 | 114
enlarged heart 3 | 210
improved glucose tolerance 3 | 79
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
decreased grip strength 2 | 116
decreased heart rate 2 | 18
decreased startle reflex 2 | 75
enlarged spleen 2 | 41
hypoactivity 2 | 132
increased circulating choleste... 2 | 66
increased erythrocyte cell num... 2 | 39
increased mean corpuscular vol... 2 | 92
increased spleen weight 2 | 10
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent startle reflex 1 | 24
absent testes 1 | 6
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased cardiac muscle contr... 1 | 11
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased monocyte cell number 1 | 8
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased aggression 1 | 4
increased circulating alkaline... 1 | 122
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating thyroxin... 1 | 7
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 115 | 11,493
ovarian cancer 94 | 8,520
osteosarcoma 92 | 7,950
glioblastoma 85 | 5,792
lung cancer 71 | 4,740
Cancer 68 | 2,499
lung carcinoma 67 | 2,843
psoriasis 67 | 6,694
medulloblastoma, large-cell 63 | 6,241
interstitial cystitis 57 | 2,312
Astrocytoma, Pilocytic 55 | 3,081
atypical teratoid / rhabdoid tumor 52 | 5,112
invasive ductal carcinoma 52 | 2,951
ependymoma 50 | 4,679
non-small cell lung cancer 47 | 2,890
adult high grade glioma 44 | 3,801
malignant mesothelioma 42 | 3,232
ulcerative colitis 42 | 1,819
Breast cancer 41 | 3,578
lung adenocarcinoma 40 | 2,716
subependymal giant cell astrocytoma 40 | 2,287
pancreatic cancer 39 | 2,398
tuberculosis 39 | 2,010
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,291
diabetes mellitus 37 | 1,728
cutaneous lupus erythematosus 35 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
oligodendroglioma 33 | 2,850
primary Sjogren syndrome 33 | 735
Rheumatoid arthritis 30 | 1,191
juvenile dermatomyositis 30 | 1,187
group 3 medulloblastoma 28 | 4,104
Multiple Sclerosis 27 | 540
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
Multiple myeloma 26 | 1,332
Pick disease 26 | 1,894
cystic fibrosis 26 | 1,696
dermatomyositis 26 | 966
Kidney cancer 25 | 2,613
ductal carcinoma in situ 25 | 1,745
primitive neuroectodermal tumor 25 | 3,035
astrocytic glioma 24 | 2,597
astrocytoma 24 | 1,146
Autosomal recessive predisposition 23 | 1,442
group 4 medulloblastoma 22 | 1,855
pituitary cancer 22 | 1,972
Duchenne muscular dystrophy 21 | 601
Schizophrenia 21 | 1,160
breast carcinoma 21 | 1,638
pediatric high grade glioma 21 | 1,064
Hypersensitivity reaction type II disease 20 | 253
Liver Cirrhosis, Experimental 20 | 769
primary pancreatic ductal adenocarcinoma 20 | 1,109
acute quadriplegic myopathy 19 | 1,158
Down syndrome 18 | 499
Waldenstrons macroglobulinemia 18 | 765
adrenocortical carcinoma 18 | 1,428
esophageal adenocarcinoma 18 | 737
nasopharyngeal carcinoma 18 | 1,058
colon cancer 17 | 1,478
active ulcerative colitis 16 | 764
gastric carcinoma 16 | 807
periodontitis 16 | 293
Arthritis 15 | 290
Kidney disease 15 | 430
active Crohn's disease 15 | 922
Alzheimer's disease 14 | 658
Asthma 14 | 385
acute myeloid leukemia 14 | 783
Anemia 12 | 365
Hepatitis B 12 | 108
Human immunodeficiency virus infectious disease 12 | 138
mucosa-associated lymphoid tissue lymphoma 12 | 484
sarcoidosis 12 | 370
Atopic dermatitis 11 | 952
Chronic Lymphocytic Leukemia 11 | 262
Crohn's disease 11 | 321
Endometriosis 11 | 540
Lymphoproliferative syndrome 11 | 58
Splenomegaly 11 | 190
Vascular disease 11 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
nephrosclerosis 11 | 333
Breast Neoplasms 10 | 445
Mammary Neoplasms 10 | 425
Neurodegenerative disease 10 | 414
Obesity 10 | 678
non primary Sjogren syndrome sicca 10 | 891
non-small cell lung carcinoma 10 | 317
pancreatic carcinoma 10 | 562
Ankylosing spondylitis 9 | 140
Atherosclerosis 9 | 291
Hepatomegaly 9 | 285
Intellectual disability 9 | 1,016
Systemic lupus erythematosus 9 | 194
head and neck cancer and chronic obstructive pulmonary disease 9 | 239
progressive supranuclear palsy 9 | 676
spina bifida 9 | 1,074
Becker muscular dystrophy 8 | 191

Tissue

Digestive Tract 144 | 17,369
Endocrine System 144 | 18,159
Female tissues 144 | 17,400
Liver and Pancreas 144 | 16,750
Male tissues 144 | 17,142
Respiratory system 144 | 16,393
Skin and soft tissues 144 | 17,230
Urinary Tract 144 | 16,678
Blood and immune system 143 | 16,909
Nervous System 143 | 16,725
Cardiovascular System 140 | 15,192

Target Family

Non-IDG 109 | 12,091
Enzyme 17 | 4,145
Transporter 16 | 473
GPCR 5 | 408
Kinase 5 | 634
Ion Channel 2 | 344

CSPA Cell Line

SU4 (SU-DHL-4) 154 | 154
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.11308 129.3 11
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.90516 156.1 254
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
Zinc transporter ZIP10 SLC39A10 Tbio Transporter -1.20558 16.3 102
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Zinc transporter ZIP6 SLC39A6 Tbio Transporter -1.66663 50.0 172
Disintegrin and metalloproteinase domain-containing protein 15 ADAM15 Tbio Enzyme -1.87408 84.1 301
Solute carrier family 12 member 6 SLC12A6 Tbio Transporter -1.73943 58.4 161