Development Level

Tbio 112 | 11,445
Tchem 23 | 1,598
Tclin 20 | 613
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 10 | 499
abnormal behavior 5 | 298
decreased total body fat amoun... 5 | 207
enlarged heart 4 | 210
abnormal seminal vesicle morph... 3 | 114
decreased vertical activity 3 | 208
enlarged spleen 3 | 41
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal sleep behavior 2 | 70
abnormal snout morphology 2 | 23
decreased body length 2 | 101
decreased heart rate 2 | 18
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating choleste... 2 | 66
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
abnormal behavioral response t... 1 | 66
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal hindlimb morphology 1 | 2
abnormal incisor morphology 1 | 4
abnormal limb position 1 | 3
abnormal liver morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal radius morphology 1 | 8
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal urination 1 | 1
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased monocyte cell number 1 | 8
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased vertical activity 1 | 24
limb grasping 1 | 41
microphthalmia 1 | 26
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 113 | 11,493
osteosarcoma 101 | 7,950
ovarian cancer 90 | 8,520
glioblastoma 75 | 5,792
lung cancer 73 | 4,740
medulloblastoma, large-cell 71 | 6,241
psoriasis 69 | 6,694
Cancer 68 | 2,499
lung carcinoma 65 | 2,843
interstitial cystitis 63 | 2,312
atypical teratoid / rhabdoid tumor 56 | 5,112
ependymoma 51 | 4,679
invasive ductal carcinoma 51 | 2,951
malignant mesothelioma 49 | 3,232
Astrocytoma, Pilocytic 47 | 3,081
ulcerative colitis 46 | 1,819
adult high grade glioma 44 | 3,801
subependymal giant cell astrocytoma 43 | 2,287
pancreatic cancer 42 | 2,398
Breast cancer 41 | 3,578
non-small cell lung cancer 40 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
cutaneous lupus erythematosus 38 | 1,057
diabetes mellitus 37 | 1,728
lung adenocarcinoma 37 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,955
tuberculosis 35 | 2,010
Rheumatoid arthritis 34 | 1,191
oligodendroglioma 32 | 2,850
primary Sjogren syndrome 31 | 735
ductal carcinoma in situ 28 | 1,745
group 3 medulloblastoma 28 | 4,104
Multiple Sclerosis 27 | 540
breast carcinoma 26 | 1,638
dermatomyositis 26 | 966
primitive neuroectodermal tumor 26 | 3,035
Kidney cancer 25 | 2,613
cystic fibrosis 25 | 1,696
Hypersensitivity reaction type II disease 24 | 253
Multiple myeloma 24 | 1,332
juvenile dermatomyositis 24 | 1,187
primary pancreatic ductal adenocarcinoma 24 | 1,109
Autosomal recessive predisposition 23 | 1,442
astrocytoma 23 | 1,146
Liver Cirrhosis, Experimental 22 | 769
Pick disease 22 | 1,894
Schizophrenia 22 | 1,160
astrocytic glioma 22 | 2,597
group 4 medulloblastoma 22 | 1,855
Duchenne muscular dystrophy 19 | 601
pituitary cancer 19 | 1,972
colon cancer 18 | 1,478
esophageal adenocarcinoma 18 | 737
Waldenstrons macroglobulinemia 17 | 765
adrenocortical carcinoma 17 | 1,428
nasopharyngeal carcinoma 17 | 1,058
Kidney disease 16 | 430
acute myeloid leukemia 16 | 783
acute quadriplegic myopathy 16 | 1,158
gastric carcinoma 16 | 807
mucosa-associated lymphoid tissue lymphoma 16 | 484
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
pediatric high grade glioma 16 | 1,064
Alzheimer's disease 15 | 658
Anemia 15 | 365
Arthritis 15 | 290
Asthma 14 | 385
Down syndrome 14 | 499
Hepatitis B 14 | 108
active Crohn's disease 14 | 922
active ulcerative colitis 14 | 764
periodontitis 14 | 293
sarcoidosis 14 | 370
Atopic dermatitis 13 | 952
Breast Neoplasms 12 | 445
Mammary Neoplasms 12 | 425
Chronic Lymphocytic Leukemia 11 | 262
Human immunodeficiency virus infectious disease 11 | 138
Hypertension 11 | 396
Lymphoproliferative syndrome 11 | 58
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
pancreatic carcinoma 11 | 562
Atherosclerosis 10 | 291
Crohn's disease 10 | 321
Endometriosis 10 | 540
Inflammatory bowel disease 10 | 151
Juvenile rheumatoid arthritis 10 | 111
Neurodegenerative disease 10 | 414
Recurrent respiratory infections 10 | 141
Systemic lupus erythematosus 10 | 194
head and neck cancer and chronic obstructive pulmonary disease 10 | 239
nephrosclerosis 10 | 333
Dermatitis 9 | 157
Fever 9 | 138
Liver disease 9 | 237
Obesity 9 | 678
Vascular disease 9 | 319
posterior fossa group A ependymoma 9 | 468
progressive supranuclear palsy 9 | 676

Tissue

Blood and immune system 148 | 16,909
Endocrine System 148 | 18,159
Female tissues 148 | 17,400
Respiratory system 148 | 16,393
Urinary Tract 148 | 16,678
Digestive Tract 147 | 17,369
Liver and Pancreas 147 | 16,750
Male tissues 147 | 17,142
Skin and soft tissues 147 | 17,230
Cardiovascular System 143 | 15,192
Nervous System 143 | 16,725

Target Family

Non-IDG 118 | 12,091
Enzyme 15 | 4,145
Transporter 14 | 473
Kinase 7 | 634
GPCR 4 | 408
Ion Channel 2 | 344

CSPA Cell Line

SU-DHL-6 160 | 160
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Leukocyte-associated immunoglobulin-like receptor 1 LAIR1 Tbio Non-IDG -1.74760 64.2 487
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Zinc transporter ZIP10 SLC39A10 Tbio Transporter -1.20558 16.3 102
T-lymphocyte surface antigen Ly-9 LY9 Tbio Non-IDG -1.58527 43.8 383
Transmembrane 9 superfamily member 3 TM9SF3 Tdark Non-IDG -1.62419 41.9 40
UL-16 binding protein 5 RAET1G Tbio Non-IDG -0.77225 5.67 20