Development Level

Tbio 143 | 11,445
Tchem 41 | 1,598
Tclin 20 | 613
Tdark 17 | 6,588

Collection

GPCR: IDG Consortium (Complete... 3 | 25
GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal behavior 7 | 298
decreased vertical activity 7 | 208
preweaning lethality, incomple... 6 | 499
abnormal embryo size 5 | 220
decreased total body fat amoun... 5 | 207
abnormal seminal vesicle morph... 4 | 114
embryonic lethality prior to t... 4 | 278
enlarged heart 4 | 210
increased heart weight 4 | 62
abnormal eye morphology 3 | 68
abnormal vibrissa morphology 3 | 25
embryonic growth retardation 3 | 106
increased bone mineral content 3 | 108
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
abnormal coat appearance 2 | 31
abnormal limb bud morphology 2 | 17
abnormal retina morphology 2 | 71
cardiovascular system phenotyp... 2 | 36
decreased body length 2 | 101
decreased cardiac muscle contr... 2 | 11
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
enlarged spleen 2 | 41
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
pallor 2 | 34
prolonged ST segment 2 | 36
tremors 2 | 39
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal response to new envir... 1 | 10
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 11
abnormal urination 1 | 1
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
absent testes 1 | 6
absent vibrissae 1 | 12
cataract 1 | 92
decreased body weight 1 | 161
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating glycerol... 1 | 16
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased monocyte cell number 1 | 8
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
increased aggression 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating calcium ... 1 | 34
increased circulating iron lev... 1 | 30
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased total retina thickne... 1 | 4
male infertility 1 | 123
microphthalmia 1 | 26
pale yolk sac 1 | 25
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
trunk curl 1 | 16
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 177 | 11,493
ovarian cancer 148 | 8,520
glioblastoma 124 | 5,792
osteosarcoma 119 | 7,950
ependymoma 98 | 4,679
Cancer 96 | 2,499
atypical teratoid / rhabdoid tumor 96 | 5,112
psoriasis 96 | 6,694
medulloblastoma, large-cell 95 | 6,241
lung cancer 94 | 4,740
lung carcinoma 91 | 2,843
malignant mesothelioma 90 | 3,232
Astrocytoma, Pilocytic 87 | 3,081
Breast cancer 79 | 3,578
invasive ductal carcinoma 78 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 74 | 2,955
adult high grade glioma 72 | 3,801
non-small cell lung cancer 71 | 2,890
lung adenocarcinoma 70 | 2,716
group 3 medulloblastoma 68 | 4,104
pancreatic cancer 68 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 63 | 3,291
subependymal giant cell astrocytoma 61 | 2,287
Kidney cancer 58 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 58 | 2,989
oligodendroglioma 58 | 2,850
interstitial cystitis 57 | 2,312
ulcerative colitis 56 | 1,819
cystic fibrosis 55 | 1,696
ductal carcinoma in situ 52 | 1,745
tuberculosis 50 | 2,010
primitive neuroectodermal tumor 49 | 3,035
primary pancreatic ductal adenocarcinoma 48 | 1,109
pancreatic ductal adenocarcinoma liver metastasis 45 | 1,962
astrocytic glioma 43 | 2,597
breast carcinoma 43 | 1,638
diabetes mellitus 40 | 1,728
gastric carcinoma 39 | 807
pituitary cancer 39 | 1,972
colon cancer 38 | 1,478
juvenile dermatomyositis 36 | 1,187
Duchenne muscular dystrophy 34 | 601
adrenocortical carcinoma 34 | 1,428
astrocytoma 32 | 1,146
Atopic dermatitis 30 | 952
group 4 medulloblastoma 30 | 1,855
acute quadriplegic myopathy 28 | 1,158
cutaneous lupus erythematosus 28 | 1,057
pediatric high grade glioma 28 | 1,064
dermatomyositis 27 | 966
esophageal adenocarcinoma 27 | 737
nasopharyngeal carcinoma 27 | 1,058
Autosomal recessive predisposition 26 | 1,442
Pick disease 26 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 26 | 510
Rheumatoid arthritis 24 | 1,191
Kidney disease 23 | 430
Liver Cirrhosis, Experimental 23 | 769
Multiple Sclerosis 23 | 540
Schizophrenia 23 | 1,160
fibroadenoma 22 | 559
active Crohn's disease 21 | 922
Hypersensitivity reaction type II disease 20 | 253
Multiple myeloma 20 | 1,332
active ulcerative colitis 20 | 764
Alzheimer's disease 19 | 658
Atherosclerosis 19 | 291
Breast Neoplasms 19 | 445
Endometriosis 19 | 540
Melanoma 19 | 711
acute myeloid leukemia 19 | 783
Arthritis 18 | 290
Down syndrome 18 | 499
Mammary Neoplasms 17 | 425
aldosterone-producing adenoma 17 | 665
Coronary artery disease 15 | 268
Hypertension 15 | 396
Liver cancer 15 | 604
Prostatic Neoplasms 15 | 495
primary Sjogren syndrome 15 | 735
spina bifida 15 | 1,074
Anemia 14 | 365
Asthma 14 | 385
Cerebrovascular disease 14 | 238
Liver disease 14 | 237
Stomach Neoplasms 14 | 300
interstitial lung disease 14 | 298
posterior fossa group A ependymoma 14 | 468
Hypertensive disease 13 | 292
Skin cancer 13 | 469
Vascular disease 13 | 319
sonic hedgehog group medulloblastoma 12 | 467
Intellectual disability 11 | 1,016
Neoplasm Invasiveness 11 | 161
Neoplasm Metastasis 11 | 168
Short stature 11 | 531
Waldenstrons macroglobulinemia 11 | 765
head and neck cancer 11 | 271
medulloblastoma 11 | 720
mucosa-associated lymphoid tissue lymphoma 11 | 484

Tissue

Endocrine System 212 | 18,159
Female tissues 212 | 17,400
Nervous System 212 | 16,725
Urinary Tract 212 | 16,678
Digestive Tract 211 | 17,369
Male tissues 211 | 17,142
Respiratory system 211 | 16,393
Liver and Pancreas 210 | 16,750
Skin and soft tissues 210 | 17,230
Blood and immune system 209 | 16,909
Cardiovascular System 206 | 15,192

Target Family

Non-IDG 150 | 12,091
Enzyme 30 | 4,145
Kinase 14 | 634
Transporter 14 | 473
GPCR 8 | 408
Ion Channel 4 | 344
Transcription Factor 1 | 1,400

CSPA Cell Line

SDM5 221 | 221
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.11308 129.3 11
Cadherin-10 CDH10 Tbio Non-IDG -0.86821 9.34 155
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
G-protein coupled receptor 39 GPR39 Tchem GPCR -1.77076 66.5 232
Trophoblast glycoprotein TPBG Tbio Non-IDG -2.10560 136.9 206
Zinc transporter ZIP10 SLC39A10 Tbio Transporter -1.20558 16.3 102
CD276 antigen CD276 Tbio Non-IDG -3.03140 785.5 481