Development Level

Tbio 145 | 11,445
Tchem 36 | 1,598
Tclin 21 | 613
Tdark 9 | 6,588

Collection

GPCR: IDG Consortium (Complete... 3 | 25
GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

preweaning lethality, incomple... 8 | 499
abnormal behavior 7 | 298
decreased total body fat amoun... 6 | 207
enlarged heart 6 | 210
decreased vertical activity 5 | 208
increased heart weight 5 | 62
increased bone mineral content 4 | 108
increased mean corpuscular vol... 4 | 92
preweaning lethality, complete... 4 | 979
abnormal seminal vesicle morph... 3 | 114
enlarged spleen 3 | 41
increased lean body mass 3 | 172
tremors 3 | 39
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal eye morphology 2 | 68
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
abnormal vibrissa morphology 2 | 25
cardiovascular system phenotyp... 2 | 36
decreased body length 2 | 101
decreased cardiac muscle contr... 2 | 11
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased startle reflex 2 | 75
dilated heart left ventricle 2 | 11
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased bone mineral density 2 | 72
increased circulating choleste... 2 | 66
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 11
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased mean corpuscular hem... 1 | 31
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
impaired righting response 1 | 26
increased aggression 1 | 4
increased body weight 1 | 25
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
male infertility 1 | 123
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prolonged PQ interval 1 | 5
short tibia 1 | 97
trunk curl 1 | 16

Disease

Carcinoma 179 | 11,493
ovarian cancer 137 | 8,520
glioblastoma 115 | 5,792
osteosarcoma 108 | 7,950
medulloblastoma, large-cell 101 | 6,241
Cancer 97 | 2,499
atypical teratoid / rhabdoid tumor 95 | 5,112
lung cancer 95 | 4,740
malignant mesothelioma 93 | 3,232
psoriasis 92 | 6,694
ependymoma 90 | 4,679
lung carcinoma 85 | 2,843
Breast cancer 82 | 3,578
Astrocytoma, Pilocytic 79 | 3,081
pancreatic cancer 78 | 2,398
non-small cell lung cancer 73 | 2,890
invasive ductal carcinoma 72 | 2,951
lung adenocarcinoma 72 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 70 | 2,955
adult high grade glioma 69 | 3,801
ulcerative colitis 69 | 1,819
group 3 medulloblastoma 62 | 4,104
interstitial cystitis 62 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 62 | 2,989
Kidney cancer 61 | 2,613
cystic fibrosis 59 | 1,696
oligodendroglioma 59 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 58 | 3,291
subependymal giant cell astrocytoma 51 | 2,287
primitive neuroectodermal tumor 50 | 3,035
astrocytic glioma 47 | 2,597
ductal carcinoma in situ 47 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 47 | 1,962
primary pancreatic ductal adenocarcinoma 47 | 1,109
tuberculosis 46 | 2,010
breast carcinoma 43 | 1,638
diabetes mellitus 43 | 1,728
pituitary cancer 41 | 1,972
gastric carcinoma 40 | 807
juvenile dermatomyositis 40 | 1,187
Duchenne muscular dystrophy 39 | 601
colon cancer 39 | 1,478
Autosomal recessive predisposition 38 | 1,442
adrenocortical carcinoma 34 | 1,428
group 4 medulloblastoma 33 | 1,855
Rheumatoid arthritis 32 | 1,191
acute quadriplegic myopathy 31 | 1,158
nasopharyngeal carcinoma 31 | 1,058
Liver Cirrhosis, Experimental 29 | 769
pediatric high grade glioma 29 | 1,064
Schizophrenia 28 | 1,160
esophageal adenocarcinoma 28 | 737
autosomal dominant Emery-Dreifuss muscular dystrophy 27 | 510
dermatomyositis 27 | 966
Pick disease 26 | 1,894
cutaneous lupus erythematosus 26 | 1,057
Atopic dermatitis 24 | 952
Breast Neoplasms 23 | 445
Alzheimer's disease 22 | 658
Mammary Neoplasms 22 | 425
astrocytoma 22 | 1,146
fibroadenoma 22 | 559
Kidney disease 21 | 430
Multiple Sclerosis 21 | 540
Multiple myeloma 20 | 1,332
Asthma 19 | 385
Coronary artery disease 19 | 268
Down syndrome 19 | 499
Melanoma 19 | 711
Atherosclerosis 18 | 291
Vascular disease 18 | 319
active Crohn's disease 18 | 922
posterior fossa group A ependymoma 18 | 468
Hypersensitivity reaction type II disease 17 | 253
Liver cancer 17 | 604
Prostatic Neoplasms 17 | 495
aldosterone-producing adenoma 17 | 665
spina bifida 17 | 1,074
Becker muscular dystrophy 16 | 191
Endometriosis 16 | 540
Liver disease 16 | 237
Neoplasm Invasiveness 16 | 161
acute myeloid leukemia 16 | 783
primary Sjogren syndrome 16 | 735
Hypertension 15 | 396
Short stature 15 | 531
head and neck cancer 15 | 271
interstitial lung disease 15 | 298
mucosa-associated lymphoid tissue lymphoma 15 | 484
non-small cell lung carcinoma 15 | 317
Neoplasm Metastasis 14 | 168
Waldenstrons macroglobulinemia 14 | 765
active ulcerative colitis 14 | 764
limb girdle muscular dystrophy 2A 14 | 213
non primary Sjogren syndrome sicca 14 | 891
sonic hedgehog group medulloblastoma 14 | 467
Arthritis 13 | 290
Cerebrovascular disease 13 | 238
Muscle hypotonia 13 | 571
urothelial carcinoma 13 | 318

Tissue

Endocrine System 205 | 18,159
Digestive Tract 204 | 17,369
Female tissues 204 | 17,400
Nervous System 204 | 16,725
Skin and soft tissues 204 | 17,230
Liver and Pancreas 203 | 16,750
Male tissues 203 | 17,142
Respiratory system 203 | 16,393
Urinary Tract 203 | 16,678
Blood and immune system 202 | 16,909
Cardiovascular System 196 | 15,192

Target Family

Non-IDG 147 | 12,091
Enzyme 26 | 4,145
Kinase 13 | 634
Transporter 11 | 473
GPCR 9 | 408
Ion Channel 3 | 344
Transcription Factor 2 | 1,400

CSPA Cell Line

SDM4 211 | 211
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
G-protein coupled receptor 39 GPR39 Tchem GPCR -1.77076 66.5 232
Trophoblast glycoprotein TPBG Tbio Non-IDG -2.10560 136.9 206
Zinc transporter ZIP10 SLC39A10 Tbio Transporter -1.20558 16.3 102
CD276 antigen CD276 Tbio Non-IDG -3.03140 785.5 481
Collagen alpha-1(XII) chain COL12A1 Tbio Non-IDG -1.36571 21.4 38
Zinc transporter ZIP6 SLC39A6 Tbio Transporter -1.66663 50.0 172
Disintegrin and metalloproteinase domain-containing protein 15 ADAM15 Tbio Enzyme -1.87408 84.1 301