Development Level

Tbio 170 | 11,445
Tchem 33 | 1,598
Tdark 25 | 6,588
Tclin 12 | 613

Collection

GPCR: IDG Consortium (Complete... 3 | 25

IMPC Phenotype

abnormal behavior 9 | 298
preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 9 | 499
decreased grip strength 5 | 116
increased bone mineral content 5 | 108
abnormal bone structure 4 | 187
decreased body length 4 | 101
decreased total body fat amoun... 4 | 207
increased heart weight 4 | 62
increased mean corpuscular vol... 4 | 92
abnormal eye morphology 3 | 68
abnormal sleep behavior 3 | 70
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
hypoactivity 3 | 132
increased lean body mass 3 | 172
abnormal behavioral response t... 2 | 66
abnormal coat appearance 2 | 31
abnormal embryo size 2 | 220
abnormal femur morphology 2 | 14
abnormal limb bud morphology 2 | 17
abnormal limb position 2 | 3
abnormal urinary bladder morph... 2 | 11
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating creatini... 2 | 39
decreased circulating glucose ... 2 | 126
decreased erythrocyte cell num... 2 | 62
decreased mean corpuscular hem... 2 | 31
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
dilated heart left ventricle 2 | 11
impaired glucose tolerance 2 | 75
increased circulating choleste... 2 | 66
increased circulating glycerol... 2 | 9
increased circulating iron lev... 2 | 30
increased circulating thyroxin... 2 | 7
increased erythrocyte cell num... 2 | 39
increased total body fat amoun... 2 | 134
pallor 2 | 34
short tibia 2 | 97
tremors 2 | 39
abnormal coat-hair pigmentatio... 1 | 64
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal tail movements 1 | 12
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
increased B cell number 1 | 9
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased vertical activity 1 | 24
pale yolk sac 1 | 25
premature death 1 | 5
prolonged RR interval 1 | 8
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 185 | 11,493
ovarian cancer 181 | 8,520
glioblastoma 146 | 5,792
osteosarcoma 141 | 7,950
medulloblastoma, large-cell 122 | 6,241
ependymoma 111 | 4,679
psoriasis 108 | 6,694
atypical teratoid / rhabdoid tumor 106 | 5,112
lung cancer 101 | 4,740
Astrocytoma, Pilocytic 96 | 3,081
Breast cancer 91 | 3,578
pancreatic cancer 91 | 2,398
invasive ductal carcinoma 90 | 2,951
Cancer 88 | 2,499
malignant mesothelioma 88 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 85 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 79 | 2,989
lung carcinoma 78 | 2,843
group 3 medulloblastoma 77 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 76 | 3,291
ulcerative colitis 75 | 1,819
lung adenocarcinoma 74 | 2,716
adult high grade glioma 73 | 3,801
non-small cell lung cancer 73 | 2,890
oligodendroglioma 66 | 2,850
primary pancreatic ductal adenocarcinoma 65 | 1,109
cystic fibrosis 64 | 1,696
Kidney cancer 62 | 2,613
primitive neuroectodermal tumor 59 | 3,035
subependymal giant cell astrocytoma 59 | 2,287
astrocytic glioma 56 | 2,597
juvenile dermatomyositis 55 | 1,187
Duchenne muscular dystrophy 52 | 601
breast carcinoma 52 | 1,638
diabetes mellitus 52 | 1,728
ductal carcinoma in situ 52 | 1,745
interstitial cystitis 50 | 2,312
tuberculosis 49 | 2,010
gastric carcinoma 48 | 807
pancreatic ductal adenocarcinoma liver metastasis 47 | 1,962
pituitary cancer 47 | 1,972
colon cancer 42 | 1,478
acute quadriplegic myopathy 41 | 1,158
adrenocortical carcinoma 41 | 1,428
group 4 medulloblastoma 41 | 1,855
Liver Cirrhosis, Experimental 39 | 769
autosomal dominant Emery-Dreifuss muscular dystrophy 39 | 510
pediatric high grade glioma 39 | 1,064
dermatomyositis 38 | 966
Pick disease 36 | 1,894
Multiple myeloma 34 | 1,332
Autosomal recessive predisposition 33 | 1,442
esophageal adenocarcinoma 31 | 737
nasopharyngeal carcinoma 29 | 1,058
Atopic dermatitis 28 | 952
Alzheimer's disease 26 | 658
Rheumatoid arthritis 25 | 1,191
active Crohn's disease 25 | 922
astrocytoma 25 | 1,146
Becker muscular dystrophy 22 | 191
Down syndrome 22 | 499
limb girdle muscular dystrophy 2A 21 | 213
Breast Neoplasms 20 | 445
active ulcerative colitis 20 | 764
cutaneous lupus erythematosus 20 | 1,057
fibroadenoma 20 | 559
medulloblastoma 20 | 720
Mammary Neoplasms 19 | 425
Multiple Sclerosis 19 | 540
Schizophrenia 19 | 1,160
mucosa-associated lymphoid tissue lymphoma 19 | 484
Prostatic Neoplasms 18 | 495
interstitial lung disease 18 | 298
Kidney disease 17 | 430
Muscle hypotonia 17 | 571
acute myeloid leukemia 17 | 783
primary Sjogren syndrome 17 | 735
Endometriosis 16 | 540
Melanoma 16 | 711
Vascular disease 16 | 319
aldosterone-producing adenoma 16 | 665
non primary Sjogren syndrome sicca 16 | 891
Waldenstrons macroglobulinemia 15 | 765
spina bifida 15 | 1,074
urothelial carcinoma 15 | 318
Acquired scoliosis 14 | 281
Curvature of spine 14 | 282
Liver cancer 14 | 604
Neoplasm Invasiveness 14 | 161
Stomach Neoplasms 14 | 300
sonic hedgehog group medulloblastoma 14 | 467
Anemia 13 | 365
Hypertensive disease 13 | 292
Short stature 13 | 531
Arthritis 12 | 290
Cardiovascular system disease 12 | 246
Hypersensitivity reaction type II disease 12 | 253
Hypertension 12 | 396
Osteoarthritis 12 | 184
progressive supranuclear palsy 12 | 676

Tissue

Blood and immune system 234 | 16,909
Endocrine System 234 | 18,159
Female tissues 234 | 17,400
Respiratory system 234 | 16,393
Urinary Tract 234 | 16,678
Digestive Tract 233 | 17,369
Liver and Pancreas 233 | 16,750
Male tissues 233 | 17,142
Nervous System 233 | 16,725
Skin and soft tissues 233 | 17,230
Cardiovascular System 232 | 15,192

Target Family

Non-IDG 168 | 12,091
Enzyme 44 | 4,145
Transporter 12 | 473
Kinase 7 | 634
GPCR 5 | 408
Ion Channel 4 | 344

CSPA Cell Line

Ruch-2 240 | 240
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Carboxypeptidase Q CPQ Tbio Enzyme -2.51783 330.9 81
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Transmembrane glycoprotein NMB GPNMB Tbio Non-IDG -2.05817 130.8 293
Leucine-rich repeat transmembrane protein FLRT2 FLRT2 Tbio Non-IDG -1.09240 12.6 50
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
Protocadherin gamma-A9 PCDHGA9 Tdark Non-IDG 0.51 0.72 31
Trophoblast glycoprotein TPBG Tbio Non-IDG -2.10560 136.9 206
CD276 antigen CD276 Tbio Non-IDG -3.03140 785.5 481