Development Level

Tbio 180 | 11,178
Tchem 42 | 1,885
Tdark 25 | 6,569
Tclin 18 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, incomple... 12 | 499
abnormal behavior 10 | 298
preweaning lethality, complete... 10 | 979
decreased vertical activity 5 | 208
abnormal bone structure 4 | 187
decreased body length 4 | 101
decreased grip strength 4 | 116
abnormal sleep behavior 3 | 70
decreased body weight 3 | 161
enlarged heart 3 | 210
impaired glucose tolerance 3 | 75
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal limb position 2 | 3
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating creatini... 2 | 39
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 31
decreased total body fat amoun... 2 | 207
enlarged uterus 2 | 11
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating glycerol... 2 | 9
increased circulating thyroxin... 2 | 7
increased fasted circulating g... 2 | 76
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
male infertility 2 | 123
abnormal behavioral response t... 1 | 66
abnormal brain morphology 1 | 13
abnormal cecum morphology 1 | 7
abnormal coat appearance 1 | 31
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased circulating bilirubi... 1 | 19
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hydrometra 1 | 53
increased B cell number 1 | 9
increased body length 1 | 32
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased exploration in new e... 1 | 8
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased vertical activity 1 | 24
pallor 1 | 34
polycystic kidney 1 | 15
premature death 1 | 5
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 192 | 11,192
ovarian cancer 185 | 8,297
glioblastoma 155 | 5,635
osteosarcoma 142 | 7,766
psoriasis 125 | 6,514
medulloblastoma, large-cell 122 | 6,086
ependymoma 120 | 4,559
atypical teratoid / rhabdoid tumor 114 | 4,971
lung cancer 105 | 4,607
Astrocytoma, Pilocytic 101 | 3,006
malignant mesothelioma 99 | 3,135
Breast cancer 96 | 3,469
lung carcinoma 86 | 2,755
pancreatic cancer 86 | 2,322
invasive ductal carcinoma 85 | 2,867
Cancer 82 | 2,388
lung adenocarcinoma 82 | 2,627
intraductal papillary-mucinous adenoma (IPMA) 81 | 2,872
non-small cell lung cancer 81 | 2,799
Kidney cancer 74 | 2,548
adult high grade glioma 74 | 3,701
intraductal papillary-mucinous carcinoma (IPMC) 74 | 2,902
oligodendroglioma 74 | 2,768
ulcerative colitis 74 | 1,765
intraductal papillary-mucinous neoplasm (IPMN) 73 | 3,204
group 3 medulloblastoma 72 | 4,002
subependymal giant cell astrocytoma 64 | 2,230
astrocytic glioma 62 | 2,530
interstitial cystitis 62 | 2,237
cystic fibrosis 61 | 1,629
primitive neuroectodermal tumor 59 | 2,957
diabetes mellitus 53 | 1,683
primary pancreatic ductal adenocarcinoma 53 | 1,071
breast carcinoma 51 | 1,589
Duchenne muscular dystrophy 50 | 587
colon cancer 50 | 1,428
juvenile dermatomyositis 50 | 1,147
ductal carcinoma in situ 48 | 1,686
group 4 medulloblastoma 48 | 1,806
pancreatic ductal adenocarcinoma liver metastasis 47 | 1,911
gastric carcinoma 46 | 781
pituitary cancer 45 | 1,915
Autosomal recessive predisposition 43 | 1,407
adrenocortical carcinoma 43 | 1,385
pediatric high grade glioma 43 | 1,035
acute quadriplegic myopathy 40 | 1,133
tuberculosis 40 | 1,963
Liver Cirrhosis, Experimental 39 | 733
Pick disease 39 | 1,856
dermatomyositis 39 | 941
Multiple myeloma 37 | 1,296
astrocytoma 32 | 1,113
Atopic dermatitis 30 | 915
Schizophrenia 29 | 1,136
autosomal dominant Emery-Dreifuss muscular dystrophy 29 | 492
Alzheimer's disease 28 | 640
esophageal adenocarcinoma 25 | 696
nasopharyngeal carcinoma 25 | 1,024
Down syndrome 24 | 480
active Crohn's disease 24 | 882
cutaneous lupus erythematosus 24 | 1,016
Intellectual disability 23 | 998
Liver cancer 22 | 589
Melanoma 22 | 689
Prostatic Neoplasms 22 | 472
aldosterone-producing adenoma 22 | 646
fibroadenoma 21 | 538
Becker muscular dystrophy 20 | 184
Multiple Sclerosis 20 | 527
Muscle hypotonia 20 | 562
Rheumatoid arthritis 20 | 1,156
Dull intelligence 19 | 634
Low intelligence 19 | 634
Mental Retardation 19 | 634
Mental deficiency 19 | 634
Poor school performance 19 | 634
Skin cancer 19 | 451
acute myeloid leukemia 19 | 760
interstitial lung disease 18 | 287
progressive supranuclear palsy 18 | 656
Breast Neoplasms 17 | 423
active ulcerative colitis 17 | 736
medulloblastoma 17 | 702
sonic hedgehog group medulloblastoma 17 | 459
Acquired scoliosis 16 | 274
Curvature of spine 16 | 275
Mammary Neoplasms 16 | 403
Neoplasm Invasiveness 16 | 151
mucosa-associated lymphoid tissue lymphoma 16 | 473
Bipolar Disorder 15 | 646
limb girdle muscular dystrophy 2A 15 | 208
Endometriosis 14 | 521
Hypertensive disease 14 | 278
Short stature 14 | 514
non-small cell lung carcinoma 14 | 302
Asthma 13 | 370
Atherosclerosis 13 | 276
Epilepsy 13 | 775
Liver carcinoma 13 | 229
pancreatic carcinoma 13 | 555

Tissue

Digestive Tract 261 | 17,369
Endocrine System 261 | 18,159
Female tissues 261 | 17,400
Liver and Pancreas 261 | 16,750
Male tissues 261 | 17,142
Nervous System 261 | 16,725
Skin and soft tissues 261 | 17,230
Blood and immune system 260 | 16,909
Urinary Tract 260 | 16,678
Respiratory system 258 | 16,393
Cardiovascular System 257 | 15,192

Target Family

Non-IDG 188 | 12,091
Enzyme 39 | 4,145
Transporter 14 | 473
Kinase 12 | 634
GPCR 7 | 408
Ion Channel 4 | 344
Transcription Factor 1 | 1,400

CSPA Cell Line

Rh28 265 | 265
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Protocadherin-7 PCDH7 Tbio Non-IDG -1.42056 26.3 248
Cathepsin D CTSD Tchem Enzyme -3.47061 2866.8 779
Insulin receptor INSR Tclin Kinase -2.50045 306.8 1417
Embigin EMB Tbio Non-IDG -2.79800 638.6 103
Fukutin-related protein FKRP Tbio Non-IDG -2.01629 107.6 173
Prostaglandin F2 receptor negative regulator PTGFRN Tbio Non-IDG -1.42165 26.8 105
SUN domain-containing ossification factor SUCO Tdark Non-IDG -2.13361 126.0 4
Translocon-associated protein subunit beta SSR2 Tbio Non-IDG -1.59509 38.4 129
C-type mannose receptor 2 MRC2 Tbio Non-IDG -1.86592 83.0 174