Development Level

Tbio 192 | 11,651
Tchem 30 | 1,388
Tdark 25 | 6,593
Tclin 18 | 612

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, incomple... 12 | 499
abnormal behavior 10 | 298
preweaning lethality, complete... 10 | 979
decreased vertical activity 5 | 208
abnormal bone structure 4 | 187
decreased body length 4 | 101
decreased grip strength 4 | 116
abnormal sleep behavior 3 | 70
decreased body weight 3 | 161
enlarged heart 3 | 210
impaired glucose tolerance 3 | 75
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal limb position 2 | 3
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating creatini... 2 | 39
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 31
decreased total body fat amoun... 2 | 207
enlarged uterus 2 | 11
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating glycerol... 2 | 9
increased circulating thyroxin... 2 | 7
increased fasted circulating g... 2 | 76
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
male infertility 2 | 123
abnormal behavioral response t... 1 | 66
abnormal brain morphology 1 | 13
abnormal cecum morphology 1 | 7
abnormal coat appearance 1 | 31
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased circulating bilirubi... 1 | 19
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hydrometra 1 | 53
increased B cell number 1 | 9
increased body length 1 | 32
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased exploration in new e... 1 | 8
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased vertical activity 1 | 24
pallor 1 | 34
polycystic kidney 1 | 15
premature death 1 | 5
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 201 | 11,493
ovarian cancer 194 | 8,520
glioblastoma 162 | 5,792
osteosarcoma 147 | 7,950
medulloblastoma, large-cell 127 | 6,241
psoriasis 126 | 6,694
ependymoma 124 | 4,679
atypical teratoid / rhabdoid tumor 120 | 5,112
lung cancer 109 | 4,740
Astrocytoma, Pilocytic 105 | 3,081
Breast cancer 101 | 3,578
malignant mesothelioma 101 | 3,232
pancreatic cancer 91 | 2,398
invasive ductal carcinoma 89 | 2,951
lung carcinoma 89 | 2,843
Cancer 88 | 2,499
lung adenocarcinoma 86 | 2,716
non-small cell lung cancer 84 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 83 | 2,955
Kidney cancer 78 | 2,613
adult high grade glioma 78 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 78 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 78 | 3,291
ulcerative colitis 78 | 1,819
oligodendroglioma 77 | 2,850
group 3 medulloblastoma 75 | 4,104
subependymal giant cell astrocytoma 67 | 2,287
astrocytic glioma 65 | 2,597
cystic fibrosis 63 | 1,696
interstitial cystitis 63 | 2,312
primitive neuroectodermal tumor 63 | 3,035
primary pancreatic ductal adenocarcinoma 58 | 1,109
Duchenne muscular dystrophy 54 | 601
diabetes mellitus 54 | 1,728
juvenile dermatomyositis 54 | 1,187
breast carcinoma 53 | 1,638
colon cancer 52 | 1,478
ductal carcinoma in situ 52 | 1,745
group 4 medulloblastoma 50 | 1,855
gastric carcinoma 49 | 807
pancreatic ductal adenocarcinoma liver metastasis 49 | 1,962
acute quadriplegic myopathy 46 | 1,158
pituitary cancer 46 | 1,972
adrenocortical carcinoma 44 | 1,428
pediatric high grade glioma 44 | 1,064
Autosomal recessive predisposition 43 | 1,442
Liver Cirrhosis, Experimental 43 | 769
Pick disease 42 | 1,894
tuberculosis 41 | 2,010
dermatomyositis 40 | 966
Multiple myeloma 39 | 1,332
astrocytoma 34 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 33 | 510
Alzheimer's disease 32 | 658
Atopic dermatitis 30 | 952
Schizophrenia 29 | 1,160
esophageal adenocarcinoma 28 | 737
nasopharyngeal carcinoma 26 | 1,058
active Crohn's disease 25 | 922
cutaneous lupus erythematosus 25 | 1,057
Down syndrome 24 | 499
Intellectual disability 23 | 1,016
Liver cancer 23 | 604
Prostatic Neoplasms 23 | 495
Rheumatoid arthritis 23 | 1,191
Melanoma 22 | 711
Multiple Sclerosis 22 | 540
aldosterone-producing adenoma 22 | 665
Becker muscular dystrophy 21 | 191
fibroadenoma 21 | 559
Muscle hypotonia 20 | 571
acute myeloid leukemia 20 | 783
Breast Neoplasms 19 | 445
Dull intelligence 19 | 645
Low intelligence 19 | 645
Mental Retardation 19 | 645
Mental deficiency 19 | 645
Poor school performance 19 | 645
Skin cancer 19 | 469
progressive supranuclear palsy 19 | 676
sonic hedgehog group medulloblastoma 19 | 467
Mammary Neoplasms 18 | 425
active ulcerative colitis 18 | 764
interstitial lung disease 18 | 298
Bipolar Disorder 17 | 666
Neoplasm Invasiveness 17 | 161
medulloblastoma 17 | 720
mucosa-associated lymphoid tissue lymphoma 17 | 484
Acquired scoliosis 16 | 281
Curvature of spine 16 | 282
Endometriosis 16 | 540
Hypertensive disease 16 | 292
limb girdle muscular dystrophy 2A 16 | 213
Asthma 15 | 385
Hypertension 15 | 396
Obesity 15 | 678
Atherosclerosis 14 | 291
Kidney disease 14 | 430
Short stature 14 | 531
Vascular disease 14 | 319

Tissue

Digestive Tract 261 | 17,369
Endocrine System 261 | 18,159
Female tissues 261 | 17,400
Liver and Pancreas 261 | 16,750
Male tissues 261 | 17,142
Nervous System 261 | 16,725
Skin and soft tissues 261 | 17,230
Blood and immune system 260 | 16,909
Urinary Tract 260 | 16,678
Respiratory system 258 | 16,393
Cardiovascular System 257 | 15,192

Target Family

Non-IDG 188 | 12,091
Enzyme 39 | 4,145
Transporter 14 | 473
Kinase 12 | 634
GPCR 7 | 408
Ion Channel 4 | 344
Transcription Factor 1 | 1,400

CSPA Cell Line

Rh28 265 | 265
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Protein disulfide-isomerase TMX3 TMX3 Tbio Enzyme -0.72922 5.29 80
Cysteine-rich with EGF-like domain protein 2 CRELD2 Tbio Non-IDG -0.79330 8.01 176
Protein tweety homolog 3 TTYH3 Tbio Ion Channel -0.17609 1.56 17
EMILIN-1 EMILIN1 Tbio Non-IDG -1.54226 36.3 0
Integrin alpha-3 ITGA3 Tbio Non-IDG -2.08360 104.1 587
Tolloid-like protein 2 TLL2 Tbio Non-IDG -1.00652 6.10 35
Semaphorin-3C SEMA3C Tbio Non-IDG -1.95299 88.1 184
Roundabout homolog 1 ROBO1 Tbio Non-IDG -2.15518 129.8 261
HEPACAM family member 2 HEPACAM2 Tbio Non-IDG -0.86200 6.23 109