Development Level

Tbio 194 | 11,445
Tchem 36 | 1,598
Tdark 30 | 6,588
Tclin 17 | 613

Collection

GPCR: IDG Consortium (Complete... 3 | 25
Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, incomple... 16 | 499
abnormal behavior 11 | 298
preweaning lethality, complete... 11 | 979
increased bone mineral content 6 | 108
abnormal bone structure 5 | 187
decreased grip strength 5 | 116
decreased total body fat amoun... 5 | 207
enlarged heart 5 | 210
decreased body length 4 | 101
decreased startle reflex 4 | 75
hyperactivity 4 | 148
impaired glucose tolerance 4 | 75
increased lean body mass 4 | 172
abnormal heart morphology 3 | 162
decreased body weight 3 | 161
decreased vertical activity 3 | 208
increased fasted circulating g... 3 | 76
increased total body fat amoun... 3 | 134
increased vertical activity 3 | 24
abnormal coat appearance 2 | 31
abnormal coat-hair pigmentatio... 2 | 64
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal limb position 2 | 3
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating triglyce... 2 | 79
decreased eosinophil cell numb... 2 | 24
decreased erythrocyte cell num... 2 | 62
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
embryonic lethality prior to t... 2 | 278
enlarged lymph nodes 2 | 37
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased circulating glycerol... 2 | 9
increased heart weight 2 | 62
increased hematocrit 2 | 46
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
male infertility 2 | 123
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
corneal opacity 1 | 32
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating insulin ... 1 | 76
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
edema 1 | 59
enlarged epididymis 1 | 31
enlarged uterus 1 | 11
hydrometra 1 | 53
increased aggression 1 | 4
increased body length 1 | 32
increased body weight 1 | 25
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased exploration in new e... 1 | 8
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
limb grasping 1 | 41
polycystic kidney 1 | 15
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
prolonged RR interval 1 | 8
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 217 | 11,493
ovarian cancer 200 | 8,520
glioblastoma 171 | 5,792
osteosarcoma 158 | 7,950
atypical teratoid / rhabdoid tumor 134 | 5,112
medulloblastoma, large-cell 132 | 6,241
psoriasis 130 | 6,694
ependymoma 129 | 4,679
lung cancer 121 | 4,740
Astrocytoma, Pilocytic 111 | 3,081
pancreatic cancer 102 | 2,398
malignant mesothelioma 101 | 3,232
invasive ductal carcinoma 100 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 98 | 2,955
Breast cancer 97 | 3,578
lung carcinoma 94 | 2,843
adult high grade glioma 90 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 90 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 90 | 3,291
Kidney cancer 86 | 2,613
group 3 medulloblastoma 85 | 4,104
lung adenocarcinoma 85 | 2,716
Cancer 84 | 2,499
non-small cell lung cancer 84 | 2,890
oligodendroglioma 82 | 2,850
ulcerative colitis 78 | 1,819
primitive neuroectodermal tumor 73 | 3,035
subependymal giant cell astrocytoma 71 | 2,287
interstitial cystitis 70 | 2,312
astrocytic glioma 63 | 2,597
cystic fibrosis 63 | 1,696
ductal carcinoma in situ 61 | 1,745
primary pancreatic ductal adenocarcinoma 61 | 1,109
juvenile dermatomyositis 60 | 1,187
Duchenne muscular dystrophy 57 | 601
diabetes mellitus 56 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 56 | 1,962
breast carcinoma 53 | 1,638
colon cancer 52 | 1,478
pituitary cancer 52 | 1,972
adrenocortical carcinoma 51 | 1,428
group 4 medulloblastoma 51 | 1,855
gastric carcinoma 50 | 807
Autosomal recessive predisposition 48 | 1,442
acute quadriplegic myopathy 46 | 1,158
pediatric high grade glioma 46 | 1,064
tuberculosis 46 | 2,010
Pick disease 43 | 1,894
Alzheimer's disease 41 | 658
Liver Cirrhosis, Experimental 41 | 769
autosomal dominant Emery-Dreifuss muscular dystrophy 41 | 510
astrocytoma 39 | 1,146
dermatomyositis 36 | 966
Multiple myeloma 35 | 1,332
Atopic dermatitis 32 | 952
nasopharyngeal carcinoma 32 | 1,058
esophageal adenocarcinoma 29 | 737
Schizophrenia 28 | 1,160
Intellectual disability 27 | 1,016
Rheumatoid arthritis 26 | 1,191
Down syndrome 25 | 499
Becker muscular dystrophy 24 | 191
Liver cancer 24 | 604
Prostatic Neoplasms 24 | 495
active Crohn's disease 24 | 922
cutaneous lupus erythematosus 24 | 1,057
Muscle hypotonia 23 | 571
interstitial lung disease 23 | 298
Dull intelligence 22 | 645
Low intelligence 22 | 645
Melanoma 22 | 711
Mental Retardation 22 | 645
Mental deficiency 22 | 645
Poor school performance 22 | 645
Multiple Sclerosis 21 | 540
acute myeloid leukemia 21 | 783
aldosterone-producing adenoma 21 | 665
fibroadenoma 21 | 559
limb girdle muscular dystrophy 2A 21 | 213
mucosa-associated lymphoid tissue lymphoma 21 | 484
Short stature 20 | 531
Obesity 19 | 678
Skin cancer 19 | 469
active ulcerative colitis 19 | 764
urothelial carcinoma 19 | 318
Breast Neoplasms 18 | 445
medulloblastoma 18 | 720
non primary Sjogren syndrome sicca 18 | 891
sonic hedgehog group medulloblastoma 18 | 467
Endometriosis 17 | 540
Epilepsy 17 | 792
Hypertensive disease 17 | 292
Mammary Neoplasms 17 | 425
Waldenstrons macroglobulinemia 17 | 765
Acquired scoliosis 16 | 281
Curvature of spine 16 | 282
Hypertension 16 | 396
Kidney disease 16 | 430
Neoplasm Invasiveness 16 | 161
Seizures 16 | 596

Tissue

Endocrine System 276 | 18,159
Female tissues 276 | 17,400
Male tissues 276 | 17,142
Skin and soft tissues 276 | 17,230
Nervous System 275 | 16,725
Blood and immune system 274 | 16,909
Digestive Tract 274 | 17,369
Liver and Pancreas 274 | 16,750
Respiratory system 274 | 16,393
Urinary Tract 274 | 16,678
Cardiovascular System 270 | 15,192

Target Family

Non-IDG 197 | 12,091
Enzyme 47 | 4,145
Transporter 11 | 473
GPCR 9 | 408
Kinase 9 | 634
Ion Channel 4 | 344

CSPA Cell Line

RD 277 | 277
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin gamma-A9 PCDHGA9 Tdark Non-IDG 0.51 0.72 31
Trophoblast glycoprotein TPBG Tbio Non-IDG -2.10560 136.9 206
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Protocadherin-18 PCDH18 Tbio Non-IDG -0.69395 5.31 87
Integrin alpha-7 ITGA7 Tbio Non-IDG -1.63563 42.4 193
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Carboxypeptidase Q CPQ Tbio Enzyme -2.51783 330.9 81
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
VPS10 domain-containing receptor SorCS1 SORCS1 Tbio Non-IDG -1.36030 24.0 81