Development Level

Tbio 147 | 11,445
Tchem 33 | 1,598
Tclin 25 | 613
Tdark 12 | 6,588

Collection

GPCR: IDG Consortium (Complete... 3 | 25
GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 8 | 499
embryonic lethality prior to t... 7 | 278
abnormal behavior 6 | 298
increased bone mineral content 5 | 108
abnormal embryo size 4 | 220
abnormal eye morphology 4 | 68
abnormal seminal vesicle morph... 4 | 114
decreased startle reflex 4 | 75
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
enlarged heart 4 | 210
increased heart weight 4 | 62
abnormal heart morphology 3 | 162
improved glucose tolerance 3 | 79
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
abnormal femur morphology 2 | 14
abnormal limb bud morphology 2 | 17
abnormal pericardium morpholog... 2 | 26
decreased circulating glucose ... 2 | 126
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
hypoactivity 2 | 132
increased bone mineral density 2 | 72
increased circulating glycerol... 2 | 9
increased circulating triglyce... 2 | 42
increased erythrocyte cell num... 2 | 39
increased hematocrit 2 | 46
increased mean corpuscular hem... 2 | 96
increased total body fat amoun... 2 | 134
pale yolk sac 2 | 25
pallor 2 | 34
prolonged ST segment 2 | 36
tremors 2 | 39
abnormal bone structure 1 | 187
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal placenta size 1 | 20
abnormal response to new envir... 1 | 10
abnormal sleep behavior 1 | 70
abnormal urinary bladder morph... 1 | 11
abnormal urination 1 | 1
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent startle reflex 1 | 24
absent testes 1 | 6
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating glycerol... 1 | 16
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
dilated heart left ventricle 1 | 11
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased body weight 1 | 25
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating thyroxin... 1 | 7
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
long tibia 1 | 25
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
trunk curl 1 | 16
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 177 | 11,493
ovarian cancer 146 | 8,520
osteosarcoma 122 | 7,950
glioblastoma 121 | 5,792
medulloblastoma, large-cell 101 | 6,241
Cancer 96 | 2,499
atypical teratoid / rhabdoid tumor 94 | 5,112
lung cancer 94 | 4,740
ependymoma 92 | 4,679
psoriasis 92 | 6,694
lung carcinoma 89 | 2,843
invasive ductal carcinoma 88 | 2,951
malignant mesothelioma 88 | 3,232
Breast cancer 84 | 3,578
Astrocytoma, Pilocytic 81 | 3,081
non-small cell lung cancer 80 | 2,890
pancreatic cancer 75 | 2,398
lung adenocarcinoma 72 | 2,716
adult high grade glioma 71 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 67 | 2,955
ulcerative colitis 66 | 1,819
intraductal papillary-mucinous carcinoma (IPMC) 65 | 2,989
Kidney cancer 62 | 2,613
interstitial cystitis 62 | 2,312
oligodendroglioma 61 | 2,850
cystic fibrosis 60 | 1,696
group 3 medulloblastoma 59 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 59 | 3,291
primary pancreatic ductal adenocarcinoma 56 | 1,109
primitive neuroectodermal tumor 55 | 3,035
ductal carcinoma in situ 53 | 1,745
subependymal giant cell astrocytoma 53 | 2,287
tuberculosis 47 | 2,010
astrocytic glioma 46 | 2,597
breast carcinoma 46 | 1,638
gastric carcinoma 45 | 807
juvenile dermatomyositis 44 | 1,187
adrenocortical carcinoma 43 | 1,428
diabetes mellitus 43 | 1,728
colon cancer 41 | 1,478
pituitary cancer 40 | 1,972
Duchenne muscular dystrophy 37 | 601
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
group 4 medulloblastoma 33 | 1,855
Pick disease 32 | 1,894
astrocytoma 32 | 1,146
dermatomyositis 32 | 966
Liver Cirrhosis, Experimental 30 | 769
autosomal dominant Emery-Dreifuss muscular dystrophy 30 | 510
acute quadriplegic myopathy 29 | 1,158
Autosomal recessive predisposition 28 | 1,442
esophageal adenocarcinoma 28 | 737
pediatric high grade glioma 28 | 1,064
Atopic dermatitis 25 | 952
Rheumatoid arthritis 25 | 1,191
Multiple Sclerosis 24 | 540
Alzheimer's disease 22 | 658
aldosterone-producing adenoma 22 | 665
Schizophrenia 21 | 1,160
cutaneous lupus erythematosus 21 | 1,057
nasopharyngeal carcinoma 21 | 1,058
Kidney disease 20 | 430
primary Sjogren syndrome 20 | 735
Breast Neoplasms 19 | 445
Multiple myeloma 19 | 1,332
Vascular disease 19 | 319
Hypertension 18 | 396
active Crohn's disease 18 | 922
fibroadenoma 18 | 559
posterior fossa group A ependymoma 18 | 468
Endometriosis 17 | 540
Hypersensitivity reaction type II disease 17 | 253
Mammary Neoplasms 17 | 425
mucosa-associated lymphoid tissue lymphoma 17 | 484
Arthritis 16 | 290
Down syndrome 16 | 499
Melanoma 16 | 711
Stomach Neoplasms 16 | 300
active ulcerative colitis 16 | 764
Anemia 15 | 365
Liver cancer 15 | 604
Liver disease 15 | 237
Prostatic Neoplasms 15 | 495
nephrosclerosis 15 | 333
sonic hedgehog group medulloblastoma 15 | 467
spina bifida 15 | 1,074
Barrett's esophagus 14 | 182
Cerebrovascular disease 13 | 238
Coronary artery disease 13 | 268
Neoplasm Invasiveness 13 | 161
Neoplasm Metastasis 13 | 168
Obesity 13 | 678
Skin cancer 13 | 469
Waldenstrons macroglobulinemia 13 | 765
acute myeloid leukemia 13 | 783
interstitial lung disease 13 | 298
medulloblastoma 13 | 720
urothelial carcinoma 13 | 318
Asthma 12 | 385
Hypertensive disease 12 | 292

Tissue

Endocrine System 209 | 18,159
Female tissues 209 | 17,400
Nervous System 209 | 16,725
Respiratory system 209 | 16,393
Blood and immune system 208 | 16,909
Digestive Tract 208 | 17,369
Male tissues 208 | 17,142
Skin and soft tissues 208 | 17,230
Liver and Pancreas 207 | 16,750
Urinary Tract 207 | 16,678
Cardiovascular System 205 | 15,192

Target Family

Non-IDG 147 | 12,091
Enzyme 27 | 4,145
Kinase 16 | 634
Transporter 14 | 473
GPCR 9 | 408
Ion Channel 3 | 344
Transcription Factor 1 | 1,400

CSPA Cell Line

PASMC 217 | 217
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Trophoblast glycoprotein TPBG Tbio Non-IDG -2.10560 136.9 206
Protocadherin gamma-B5 PCDHGB5 Tdark Non-IDG 0.00000 25
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.11308 129.3 11
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Leucine-rich repeat transmembrane protein FLRT2 FLRT2 Tbio Non-IDG -1.09240 12.6 50