Development Level

Tbio 158 | 11,445
Tchem 40 | 1,598
Tclin 23 | 613
Tdark 6 | 6,588

Collection

GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

enlarged heart 9 | 210
preweaning lethality, complete... 9 | 979
abnormal behavior 8 | 298
preweaning lethality, incomple... 8 | 499
abnormal seminal vesicle morph... 6 | 114
abnormal heart morphology 5 | 162
abnormal eye morphology 4 | 68
decreased grip strength 4 | 116
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
enlarged spleen 4 | 41
abnormal embryo size 3 | 220
abnormal limb bud morphology 3 | 17
embryonic lethality prior to t... 3 | 278
hydrometra 3 | 53
increased bone mineral content 3 | 108
increased circulating choleste... 3 | 66
increased heart weight 3 | 62
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
abnormal bone structure 2 | 187
abnormal coat appearance 2 | 31
abnormal kidney morphology 2 | 65
abnormal neural tube closure 2 | 46
decreased body length 2 | 101
decreased cardiac muscle contr... 2 | 11
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased heart rate 2 | 18
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
female infertility 2 | 60
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased erythrocyte cell num... 2 | 39
increased fasted circulating g... 2 | 76
increased mean corpuscular vol... 2 | 92
male infertility 2 | 123
pale yolk sac 2 | 25
pallor 2 | 34
small superior vagus ganglion 2 | 74
tremors 2 | 39
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal chorioallantoic fusio... 1 | 8
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal left-right axis patte... 1 | 2
abnormal lens morphology 1 | 81
abnormal neural tube morpholog... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal snout morphology 1 | 23
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tail bud morphology 1 | 8
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 11
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
absent vibrissae 1 | 12
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased total retina thickne... 1 | 17
dilated heart left ventricle 1 | 11
edema 1 | 59
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
increased aggression 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating creatini... 1 | 38
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
polycystic kidney 1 | 15
syndactyly 1 | 23

Disease

Carcinoma 170 | 11,493
ovarian cancer 145 | 8,520
osteosarcoma 123 | 7,950
glioblastoma 120 | 5,792
psoriasis 114 | 6,694
Cancer 112 | 2,499
lung cancer 100 | 4,740
atypical teratoid / rhabdoid tumor 98 | 5,112
medulloblastoma, large-cell 95 | 6,241
lung carcinoma 93 | 2,843
ependymoma 90 | 4,679
malignant mesothelioma 90 | 3,232
Breast cancer 80 | 3,578
Astrocytoma, Pilocytic 77 | 3,081
invasive ductal carcinoma 77 | 2,951
non-small cell lung cancer 77 | 2,890
adult high grade glioma 75 | 3,801
interstitial cystitis 74 | 2,312
pancreatic cancer 73 | 2,398
ulcerative colitis 72 | 1,819
intraductal papillary-mucinous carcinoma (IPMC) 71 | 2,989
lung adenocarcinoma 70 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 69 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 65 | 2,955
cystic fibrosis 60 | 1,696
group 3 medulloblastoma 59 | 4,104
Kidney cancer 58 | 2,613
oligodendroglioma 57 | 2,850
subependymal giant cell astrocytoma 57 | 2,287
tuberculosis 53 | 2,010
diabetes mellitus 48 | 1,728
primitive neuroectodermal tumor 48 | 3,035
ductal carcinoma in situ 46 | 1,745
primary pancreatic ductal adenocarcinoma 44 | 1,109
breast carcinoma 41 | 1,638
Autosomal recessive predisposition 40 | 1,442
astrocytic glioma 40 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 40 | 1,962
Rheumatoid arthritis 39 | 1,191
gastric carcinoma 39 | 807
group 4 medulloblastoma 39 | 1,855
Multiple Sclerosis 36 | 540
colon cancer 36 | 1,478
cutaneous lupus erythematosus 36 | 1,057
juvenile dermatomyositis 36 | 1,187
adrenocortical carcinoma 35 | 1,428
pituitary cancer 35 | 1,972
astrocytoma 33 | 1,146
dermatomyositis 33 | 966
Duchenne muscular dystrophy 32 | 601
esophageal adenocarcinoma 30 | 737
Pick disease 29 | 1,894
Liver Cirrhosis, Experimental 28 | 769
acute quadriplegic myopathy 27 | 1,158
nasopharyngeal carcinoma 27 | 1,058
primary Sjogren syndrome 27 | 735
Hypersensitivity reaction type II disease 26 | 253
Multiple myeloma 24 | 1,332
pediatric high grade glioma 24 | 1,064
active Crohn's disease 23 | 922
Arthritis 22 | 290
Breast Neoplasms 21 | 445
Schizophrenia 21 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 21 | 510
mucosa-associated lymphoid tissue lymphoma 21 | 484
Atopic dermatitis 20 | 952
Down syndrome 20 | 499
Endometriosis 20 | 540
Kidney disease 20 | 430
Mammary Neoplasms 20 | 425
Anemia 19 | 365
aldosterone-producing adenoma 19 | 665
Alzheimer's disease 18 | 658
Liver cancer 18 | 604
active ulcerative colitis 18 | 764
fibroadenoma 18 | 559
acute myeloid leukemia 17 | 783
non-small cell lung carcinoma 17 | 317
spina bifida 17 | 1,074
Melanoma 16 | 711
Prostatic Neoplasms 16 | 495
Vascular disease 16 | 319
Asthma 15 | 385
Intellectual disability 15 | 1,016
Waldenstrons macroglobulinemia 15 | 765
sarcoidosis 15 | 370
Acquired immunodeficiency syndrome 14 | 197
Hypertension 14 | 396
Proteinuria 14 | 144
Atherosclerosis 13 | 291
Dull intelligence 13 | 645
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Obesity 13 | 678
Poor school performance 13 | 645
Seizures 13 | 596
hepatocellular carcinoma 13 | 547
progressive supranuclear palsy 13 | 676
sonic hedgehog group medulloblastoma 13 | 467

Tissue

Endocrine System 215 | 18,159
Female tissues 215 | 17,400
Respiratory system 215 | 16,393
Blood and immune system 214 | 16,909
Digestive Tract 214 | 17,369
Skin and soft tissues 214 | 17,230
Male tissues 213 | 17,142
Nervous System 213 | 16,725
Urinary Tract 213 | 16,678
Liver and Pancreas 212 | 16,750
Cardiovascular System 210 | 15,192

Target Family

Non-IDG 162 | 12,091
Enzyme 21 | 4,145
Kinase 14 | 634
Transporter 14 | 473
GPCR 11 | 408
Ion Channel 4 | 344
Transcription Factor 1 | 1,400

CSPA Cell Line

P493-6 227 | 227
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Mucin-16 MUC16 Tbio Non-IDG -2.09951 138.4 0
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.11308 129.3 11
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303