Development Level

Tbio 119 | 11,445
Tchem 28 | 1,598
Tclin 24 | 613
Tdark 11 | 6,588

Collection

GPCR: IDG Consortium (Complete... 3 | 25
GPCR: IDG Consortium (Targets) 3 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
abnormal behavior 5 | 298
enlarged heart 4 | 210
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
decreased body length 2 | 101
decreased startle reflex 2 | 75
enlarged epididymis 2 | 31
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
increased spleen weight 2 | 10
male infertility 2 | 123
abnormal anxiety-related respo... 1 | 1
abnormal bone structure 1 | 187
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal placenta size 1 | 20
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal social-conspecific in... 1 | 3
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cataract 1 | 92
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating glycerol... 1 | 16
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased monocyte cell number 1 | 8
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased aggression 1 | 4
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
limb grasping 1 | 41
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, complete... 1 | 979
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 130 | 11,493
osteosarcoma 113 | 7,950
ovarian cancer 92 | 8,520
Cancer 84 | 2,499
lung carcinoma 81 | 2,843
psoriasis 81 | 6,694
interstitial cystitis 77 | 2,312
lung cancer 77 | 4,740
glioblastoma 75 | 5,792
medulloblastoma, large-cell 65 | 6,241
tuberculosis 58 | 2,010
Astrocytoma, Pilocytic 53 | 3,081
non-small cell lung cancer 53 | 2,890
invasive ductal carcinoma 50 | 2,951
atypical teratoid / rhabdoid tumor 49 | 5,112
adult high grade glioma 48 | 3,801
malignant mesothelioma 48 | 3,232
ulcerative colitis 47 | 1,819
lung adenocarcinoma 46 | 2,716
ependymoma 45 | 4,679
cutaneous lupus erythematosus 43 | 1,057
Breast cancer 42 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
pancreatic cancer 39 | 2,398
Rheumatoid arthritis 38 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 38 | 2,955
Multiple Sclerosis 37 | 540
diabetes mellitus 36 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 36 | 2,989
subependymal giant cell astrocytoma 34 | 2,287
Hypersensitivity reaction type II disease 32 | 253
group 3 medulloblastoma 32 | 4,104
primary Sjogren syndrome 30 | 735
dermatomyositis 28 | 966
Liver Cirrhosis, Experimental 27 | 769
cystic fibrosis 27 | 1,696
oligodendroglioma 27 | 2,850
juvenile dermatomyositis 26 | 1,187
Kidney cancer 25 | 2,613
mucosa-associated lymphoid tissue lymphoma 25 | 484
Arthritis 24 | 290
Autosomal recessive predisposition 24 | 1,442
pituitary cancer 24 | 1,972
Multiple myeloma 23 | 1,332
primary pancreatic ductal adenocarcinoma 23 | 1,109
Schizophrenia 22 | 1,160
ductal carcinoma in situ 22 | 1,745
primitive neuroectodermal tumor 22 | 3,035
Human immunodeficiency virus infectious disease 21 | 138
gastric carcinoma 21 | 807
group 4 medulloblastoma 21 | 1,855
Asthma 19 | 385
Kidney disease 19 | 430
acute myeloid leukemia 19 | 783
astrocytic glioma 19 | 2,597
periodontitis 19 | 293
Anemia 18 | 365
Duchenne muscular dystrophy 18 | 601
active Crohn's disease 18 | 922
astrocytoma 18 | 1,146
breast carcinoma 18 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
pediatric high grade glioma 18 | 1,064
Pick disease 17 | 1,894
Waldenstrons macroglobulinemia 17 | 765
esophageal adenocarcinoma 17 | 737
Liver disease 16 | 237
Vascular disease 16 | 319
acute quadriplegic myopathy 16 | 1,158
nasopharyngeal carcinoma 16 | 1,058
Down syndrome 15 | 499
Hepatitis B 15 | 108
adrenocortical carcinoma 15 | 1,428
Atherosclerosis 14 | 291
Breast Neoplasms 14 | 445
Mammary Neoplasms 14 | 425
active ulcerative colitis 14 | 764
head and neck cancer and chronic obstructive pulmonary disease 14 | 239
Alzheimer's disease 13 | 658
Ankylosing spondylitis 13 | 140
Endometriosis 13 | 540
Inflammatory bowel disease 13 | 151
Lymphoproliferative syndrome 13 | 58
colon cancer 13 | 1,478
nephrosclerosis 13 | 333
sarcoidosis 13 | 370
Chronic Lymphocytic Leukemia 12 | 262
Crohn's disease 12 | 321
Atopic dermatitis 11 | 952
Dermatitis 11 | 157
Hepatomegaly 11 | 285
Juvenile rheumatoid arthritis 11 | 111
Thrombocytopenia 11 | 197
Bipolar Disorder 10 | 666
Coronary artery disease 10 | 268
Epilepsy 10 | 792
Splenomegaly 10 | 190
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
hepatocellular carcinoma 10 | 547
pancreatic carcinoma 10 | 562

Tissue

Blood and immune system 165 | 16,909
Digestive Tract 164 | 17,369
Liver and Pancreas 164 | 16,750
Respiratory system 164 | 16,393
Endocrine System 163 | 18,159
Female tissues 163 | 17,400
Urinary Tract 163 | 16,678
Male tissues 162 | 17,142
Skin and soft tissues 162 | 17,230
Cardiovascular System 160 | 15,192
Nervous System 159 | 16,725

Target Family

Non-IDG 130 | 12,091
GPCR 20 | 408
Transporter 12 | 473
Enzyme 11 | 4,145
Ion Channel 6 | 344
Kinase 3 | 634

CSPA Cell Line

NK cells 182 | 182
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Leukocyte-associated immunoglobulin-like receptor 1 LAIR1 Tbio Non-IDG -1.74760 64.2 487
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.11308 129.3 11
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Prostaglandin D2 receptor 2 PTGDR2 Tchem GPCR -2.38441 265.9 439
Solute carrier organic anion transporter family member 3A1 SLCO3A1 Tbio Transporter -1.39614 24.1 46
Zinc transporter ZIP6 SLC39A6 Tbio Transporter -1.66663 50.0 172