Development Level

Tbio 209 | 11,651
Tchem 41 | 1,388
Tdark 36 | 6,593
Tclin 19 | 612

Collection

GPCR: IDG Consortium (Complete... 2 | 25
RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 12 | 499
abnormal behavior 7 | 298
enlarged heart 7 | 210
increased lean body mass 6 | 172
increased total body fat amoun... 6 | 134
decreased grip strength 5 | 116
decreased total body fat amoun... 5 | 207
increased bone mineral content 5 | 108
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
abnormal skin morphology 4 | 50
decreased vertical activity 4 | 208
embryonic lethality prior to t... 4 | 278
abnormal coat appearance 3 | 31
abnormal coat-hair pigmentatio... 3 | 64
abnormal eye morphology 3 | 68
abnormal heart morphology 3 | 162
abnormal limb bud morphology 3 | 17
abnormal sleep behavior 3 | 70
decreased body length 3 | 101
decreased bone mineral density 3 | 126
decreased circulating glucose ... 3 | 126
decreased circulating triglyce... 3 | 79
decreased erythrocyte cell num... 3 | 62
decreased fasted circulating g... 3 | 65
decreased startle reflex 3 | 75
enlarged spleen 3 | 41
hyperactivity 3 | 148
hypoactivity 3 | 132
impaired glucose tolerance 3 | 75
improved glucose tolerance 3 | 79
increased circulating choleste... 3 | 66
increased mean corpuscular vol... 3 | 92
pallor 3 | 34
tremors 3 | 39
abnormal behavioral response t... 2 | 66
abnormal bone mineralization 2 | 38
abnormal gait 2 | 69
abnormal kidney morphology 2 | 65
abnormal limb position 2 | 3
abnormal lung morphology 2 | 26
abnormal pericardium morpholog... 2 | 26
abnormal seminal vesicle morph... 2 | 114
abnormal urinary bladder morph... 2 | 11
abnormal vibrissa morphology 2 | 25
cardiovascular system phenotyp... 2 | 36
decreased body weight 2 | 161
decreased circulating choleste... 2 | 93
decreased circulating glycerol... 2 | 16
decreased heart rate 2 | 18
decreased lean body mass 2 | 135
decreased mean corpuscular hem... 2 | 31
decreased prepulse inhibition 2 | 82
embryonic growth retardation 2 | 106
increased B cell number 2 | 9
increased body weight 2 | 25
increased circulating glycerol... 2 | 9
increased heart weight 2 | 62
increased startle reflex 2 | 112
male infertility 2 | 123
pale yolk sac 2 | 25
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal head morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal retina morphology 1 | 71
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
absent vibrissae 1 | 12
cataract 1 | 92
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased circulating calcium ... 1 | 36
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased neutrophil cell numb... 1 | 42
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
increased aggression 1 | 4
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
long tibia 1 | 25
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
small superior vagus ganglion 1 | 74
unresponsive to tactile stimul... 1 | 8
vertebral fusion 1 | 23

Disease

Carcinoma 240 | 11,493
ovarian cancer 196 | 8,520
glioblastoma 169 | 5,792
osteosarcoma 162 | 7,950
psoriasis 141 | 6,694
medulloblastoma, large-cell 133 | 6,241
atypical teratoid / rhabdoid tumor 123 | 5,112
lung cancer 119 | 4,740
ependymoma 117 | 4,679
Breast cancer 110 | 3,578
Astrocytoma, Pilocytic 109 | 3,081
malignant mesothelioma 108 | 3,232
invasive ductal carcinoma 105 | 2,951
Cancer 103 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 95 | 2,955
lung carcinoma 94 | 2,843
non-small cell lung cancer 93 | 2,890
adult high grade glioma 90 | 3,801
group 3 medulloblastoma 90 | 4,104
pancreatic cancer 89 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 88 | 3,291
lung adenocarcinoma 84 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 83 | 2,989
subependymal giant cell astrocytoma 81 | 2,287
oligodendroglioma 80 | 2,850
Kidney cancer 79 | 2,613
interstitial cystitis 74 | 2,312
cystic fibrosis 71 | 1,696
ulcerative colitis 66 | 1,819
diabetes mellitus 65 | 1,728
breast carcinoma 61 | 1,638
primitive neuroectodermal tumor 59 | 3,035
ductal carcinoma in situ 58 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 58 | 1,962
primary pancreatic ductal adenocarcinoma 58 | 1,109
astrocytic glioma 56 | 2,597
tuberculosis 56 | 2,010
juvenile dermatomyositis 54 | 1,187
pituitary cancer 53 | 1,972
colon cancer 51 | 1,478
Pick disease 47 | 1,894
adrenocortical carcinoma 46 | 1,428
Autosomal recessive predisposition 45 | 1,442
group 4 medulloblastoma 45 | 1,855
Duchenne muscular dystrophy 44 | 601
gastric carcinoma 43 | 807
pediatric high grade glioma 42 | 1,064
dermatomyositis 40 | 966
astrocytoma 39 | 1,146
Rheumatoid arthritis 36 | 1,191
esophageal adenocarcinoma 36 | 737
cutaneous lupus erythematosus 34 | 1,057
autosomal dominant Emery-Dreifuss muscular dystrophy 33 | 510
Schizophrenia 32 | 1,160
active Crohn's disease 32 | 922
acute quadriplegic myopathy 32 | 1,158
Multiple Sclerosis 31 | 540
Multiple myeloma 30 | 1,332
Alzheimer's disease 28 | 658
Down syndrome 26 | 499
Liver Cirrhosis, Experimental 26 | 769
nasopharyngeal carcinoma 26 | 1,058
Melanoma 25 | 711
active ulcerative colitis 25 | 764
Intellectual disability 23 | 1,016
Atopic dermatitis 22 | 952
Breast Neoplasms 22 | 445
Endometriosis 22 | 540
Kidney disease 22 | 430
Mammary Neoplasms 22 | 425
fibroadenoma 22 | 559
primary Sjogren syndrome 22 | 735
mucosa-associated lymphoid tissue lymphoma 21 | 484
Obesity 20 | 678
progressive supranuclear palsy 20 | 676
Atherosclerosis 19 | 291
Hypersensitivity reaction type II disease 19 | 253
aldosterone-producing adenoma 19 | 665
Coronary artery disease 18 | 268
Dull intelligence 18 | 645
Low intelligence 18 | 645
Mental Retardation 18 | 645
Mental deficiency 18 | 645
Neurodegenerative disease 18 | 414
Poor school performance 18 | 645
Waldenstrons macroglobulinemia 18 | 765
acute myeloid leukemia 18 | 783
posterior fossa group A ependymoma 18 | 468
spina bifida 18 | 1,074
Muscle hypotonia 17 | 571
Vascular disease 17 | 319
Arthritis 16 | 290
non primary Sjogren syndrome sicca 16 | 891
Anemia 15 | 365
Bipolar Disorder 15 | 666
Epilepsy 15 | 792
Liver cancer 15 | 604
Prostatic Neoplasms 15 | 495
Skin cancer 15 | 469
sonic hedgehog group medulloblastoma 15 | 467

Tissue

Endocrine System 293 | 18,159
Female tissues 293 | 17,400
Skin and soft tissues 293 | 17,230
Blood and immune system 292 | 16,909
Liver and Pancreas 292 | 16,750
Male tissues 292 | 17,142
Nervous System 292 | 16,725
Respiratory system 292 | 16,393
Urinary Tract 292 | 16,678
Digestive Tract 291 | 17,369
Cardiovascular System 285 | 15,192

Target Family

Non-IDG 209 | 12,091
Enzyme 51 | 4,145
Transporter 19 | 473
GPCR 11 | 408
Kinase 9 | 634
Ion Channel 6 | 344

CSPA Cell Line

Melanoma NSph 305 | 305
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
Protein disulfide-isomerase TMX3 TMX3 Tbio Enzyme -0.72922 5.29 80
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Protein tweety homolog 3 TTYH3 Tbio Ion Channel -0.17609 1.56 17
Interleukin-6 receptor subunit beta IL6ST Tclin Non-IDG -1.72489 55.4 555
EMILIN-1 EMILIN1 Tbio Non-IDG -1.54226 36.3 0
Integrin alpha-9 ITGA9 Tbio Non-IDG -1.46619 29.0 124
Integrin beta-8 ITGB8 Tbio Non-IDG -1.47947 27.7 99
Integrin alpha-3 ITGA3 Tbio Non-IDG -2.08360 104.1 587