Development Level

Tbio 189 | 10,625
Tchem 58 | 1,890
Tdark 39 | 7,003
Tclin 19 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 2 | 24
GPCR: IDG Consortium (Targets) 1 | 128
Ion Channel: IDG Consortium (Targets) 1 | 102

IMPC Phenotype

preweaning lethality, complete... 10 | 633
abnormal behavior 7 | 226
preweaning lethality, incomple... 7 | 260
decreased total body fat amoun... 6 | 186
decreased lean body mass 5 | 195
enlarged heart 5 | 111
increased lean body mass 4 | 107
abnormal bone structure 3 | 131
abnormal coat appearance 3 | 25
abnormal coat-hair pigmentatio... 3 | 54
abnormal retina morphology 3 | 100
abnormal sleep behavior 3 | 63
decreased bone mineral density 3 | 126
decreased erythrocyte cell num... 3 | 43
decreased grip strength 3 | 123
embryonic lethality prior to t... 3 | 187
hypoactivity 3 | 89
impaired glucose tolerance 3 | 52
increased B cell number 3 | 23
increased body weight 3 | 42
increased bone mineral content 3 | 92
increased mean corpuscular hem... 3 | 93
increased or absent threshold ... 3 | 128
short tibia 3 | 82
straub tail 3 | 26
tremors 3 | 34
abnormal QRS complex 2 | 25
abnormal bone mineralization 2 | 55
abnormal gait 2 | 51
abnormal limb position 2 | 3
abnormal lung morphology 2 | 15
cardiovascular system phenotyp... 2 | 35
decreased body length 2 | 108
decreased body weight 2 | 174
decreased circulating glycerol... 2 | 19
decreased eosinophil cell numb... 2 | 41
decreased fasted circulating g... 2 | 49
decreased monocyte cell number 2 | 28
decreased rib number 2 | 59
enlarged spleen 2 | 26
hyperactivity 2 | 108
improved glucose tolerance 2 | 56
increased circulating glycerol... 2 | 11
increased circulating thyroxin... 2 | 7
increased exploration in new e... 2 | 56
increased grip strength 2 | 83
increased mean corpuscular vol... 2 | 91
vertebral fusion 2 | 23
abnormal behavioral response t... 1 | 52
abnormal ear morphology 1 | 5
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
abnormal tail movements 1 | 12
abnormal thoracic vertebrae mo... 1 | 16
abnormal urinary bladder morph... 1 | 2
abnormal vibrissa morphology 1 | 17
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased cardiac muscle contr... 1 | 5
decreased caudal vertebrae num... 1 | 49
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating triglyce... 1 | 83
decreased heart rate 1 | 10
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased neutrophil cell numb... 1 | 37
decreased threshold for audito... 1 | 32
enlarged heart atrium 1 | 2
enlarged lymph nodes 1 | 27
increased NK cell number 1 | 19
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 25
increased mean platelet volume 1 | 19
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
long tibia 1 | 13
persistence of hyaloid vascula... 1 | 22
premature death 1 | 5
prenatal lethality prior to he... 1 | 64
prolonged PR interval 1 | 4
thrombocytopenia 1 | 46

Disease

ovarian cancer 197 | 8,491
osteosarcoma 162 | 7,933
glioblastoma 160 | 5,572
psoriasis 141 | 6,685
medulloblastoma, large-cell 133 | 6,234
lung cancer 115 | 4,473
pilocytic astrocytoma 109 | 3,086
invasive ductal carcinoma 105 | 2,950
malignant mesothelioma 104 | 3,163
atypical teratoid / rhabdoid tumor 103 | 4,369
Cancer 99 | 2,346
Breast cancer 97 | 3,098
intraductal papillary-mucinous adenoma (IPMA) 96 | 2,956
lung carcinoma 95 | 2,844
pediatric high grade glioma 90 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 89 | 3,289
non-small cell lung cancer 89 | 2,798
pancreatic cancer 85 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 84 | 2,988
lung adenocarcinoma 84 | 2,714
subependymal giant cell astrocytoma 82 | 2,287
ulcerative colitis 81 | 2,087
oligodendroglioma 80 | 2,849
Carcinoma 74 | 2,147
interstitial cystitis 74 | 2,299
cystic fibrosis 71 | 1,670
primary pancreatic ductal adenocarcinoma 66 | 1,271
ependymoma 65 | 2,514
diabetes mellitus 63 | 1,663
breast carcinoma 60 | 1,614
primitive neuroectodermal tumor 59 | 3,031
ductal carcinoma in situ 58 | 1,745
group 4 medulloblastoma 58 | 1,875
juvenile dermatomyositis 55 | 1,189
pituitary cancer 53 | 1,972
colon cancer 51 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 51 | 1,795
astrocytoma 49 | 1,493
posterior fossa group A ependymoma 48 | 1,511
tuberculosis 48 | 1,563
Pick disease 47 | 1,893
astrocytic glioma 47 | 2,241
adrenocortical carcinoma 46 | 1,427
gastric carcinoma 46 | 832
Duchenne muscular dystrophy 45 | 602
group 3 medulloblastoma 44 | 2,254
adult high grade glioma 43 | 2,148
dermatomyositis 41 | 966
sonic hedgehog group medulloblastoma 38 | 1,482
esophageal adenocarcinoma 36 | 737
cutaneous lupus erythematosus 35 | 1,056
Rheumatoid Arthritis 33 | 1,170
Multiple myeloma 32 | 1,327
active Crohn's disease 32 | 918
acute quadriplegic myopathy 32 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 32 | 499
atypical teratoid/rhabdoid tumor 31 | 1,095
Alzheimer's disease 27 | 644
Multiple Sclerosis 27 | 498
Down syndrome 26 | 548
nasopharyngeal carcinoma 26 | 1,056
posterior fossa group B ependymoma 26 | 1,530
medulloblastoma 23 | 1,524
primary Sjogren syndrome 23 | 788
Atopic dermatitis 22 | 944
Endometriosis 22 | 535
Mammary Neoplasms 22 | 410
fibroadenoma 22 | 557
mucosa-associated lymphoid tissue lymphoma 21 | 480
progressive supranuclear palsy 20 | 674
Obesity 19 | 616
aldosterone-producing adenoma 19 | 664
Kidney disease 18 | 397
Waldenstrons macroglobulinemia 18 | 764
acute myeloid leukemia 18 | 785
Hypersensitivity reaction type II disease 17 | 235
spina bifida 17 | 1,064
Asthma 16 | 349
Atherosclerosis 16 | 275
non-small cell lung carcinoma 16 | 413
Arthritis 15 | 248
Coronary artery disease 15 | 240
Prostatic Neoplasms 15 | 471
interstitial lung disease 15 | 292
non primary Sjogren syndrome sicca 15 | 840
Anemia 14 | 252
Autistic Disorder 14 | 320
Becker muscular dystrophy 14 | 187
Colorectal Neoplasms 14 | 217
Melanoma 14 | 261
Neurodegenerative disease 14 | 383
Vascular disease 14 | 281
glioblastoma multiforme 14 | 347
pancreatic carcinoma 14 | 567
Intellectual disability 13 | 573
active ulcerative colitis 13 | 477
head and neck cancer 13 | 270
nephrosclerosis 13 | 329
Crohn's disease 12 | 304
Heart disease 12 | 279

Tissue

Cardiovascular System 298 | 17,957
Digestive Tract 298 | 18,472
Female tissues 298 | 18,646
Nervous System 298 | 18,560
Blood and immune system 297 | 17,994
Endocrine System 297 | 18,511
Liver and Pancreas 297 | 18,135
Male tissues 297 | 17,968
Urinary Tract 297 | 18,443
Respiratory system 296 | 17,483
Skin and soft tissues 293 | 18,114

Target Family

Non-IDG 209 | 11,969
Enzyme 51 | 4,146
Transporter 19 | 473
GPCR 11 | 408
Kinase 9 | 634
Ion Channel 6 | 341

CSPA Cell Line

Melanoma NSph 305 | 305
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-cell surface protein tactile CD96 Tbio Non-IDG -2.03517 108.7 142
Insulin-like growth factor-binding protein 3 IGFBP3 Tchem Non-IDG -3.34747 2121.3 411
N-acetylglucosamine-1-phosphotransferase subunit gamma GNPTG Tbio Enzyme -1.17901 15.7 80
Folate receptor alpha FOLR1 Tchem Non-IDG -2.27944 181.4 235
Sodium/potassium-transporting ATPase subunit beta-3 ATP1B3 Tclin Transporter -1.08214 10.9 189
Metalloproteinase inhibitor 1 TIMP1 Tbio Enzyme -3.55219 3513.4 673
Endothelial protein C receptor PROCR Tbio Non-IDG -2.67797 519.6 324
Receptor-type tyrosine-protein phosphatase mu PTPRM Tbio Enzyme -1.82872 68.8 135
Proteinase-activated receptor 1 F2R Tclin GPCR -2.76897 534.6 399
Dipeptidyl peptidase 4 DPP4 Tclin Enzyme -3.60140 4091.0 900