Development Level

Tbio 110 | 10,625
Tchem 37 | 1,890
Tclin 28 | 602
Tdark 14 | 7,003

Collection

GPCR: IDG Consortium (Complete/Control) 1 | 24
Ion Channel: IDG Consortium (Targets) 1 | 102

IMPC Phenotype

decreased total body fat amoun... 5 | 186
preweaning lethality, incomple... 5 | 260
abnormal behavior 4 | 226
preweaning lethality, complete... 4 | 633
abnormal bone structure 2 | 131
decreased body weight 2 | 174
decreased bone mineral density 2 | 126
decreased circulating triglyce... 2 | 83
decreased eosinophil cell numb... 2 | 41
decreased erythrocyte cell num... 2 | 43
decreased heart rate 2 | 10
decreased lean body mass 2 | 195
decreased leukocyte cell numbe... 2 | 54
decreased monocyte cell number 2 | 28
decreased prepulse inhibition 2 | 52
decreased rib number 2 | 59
enlarged heart 2 | 111
enlarged spleen 2 | 26
hypoactivity 2 | 89
impaired glucose tolerance 2 | 52
improved glucose tolerance 2 | 56
increased B cell number 2 | 23
increased body weight 2 | 42
increased circulating total pr... 2 | 20
increased grip strength 2 | 83
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
straub tail 2 | 26
abnormal QRS complex 1 | 25
abnormal bone mineralization 1 | 55
abnormal cervical vertebrae mo... 1 | 4
abnormal coat appearance 1 | 25
abnormal digit morphology 1 | 13
abnormal ear morphology 1 | 5
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal pancreas morphology 1 | 6
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal tail movements 1 | 12
abnormal thoracic vertebrae mo... 1 | 16
abnormal vibrissa morphology 1 | 17
absent startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 35
decreased CD4-positive, alpha ... 1 | 19
decreased CD5-positive Ly6C-po... 1 | 4
decreased CD8-positive, alpha-... 1 | 26
decreased Ly6C low monocyte nu... 1 | 23
decreased T cell number 1 | 31
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased cardiac muscle contr... 1 | 5
decreased caudal vertebrae num... 1 | 49
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased grip strength 1 | 123
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased startle reflex 1 | 48
decreased threshold for audito... 1 | 32
enlarged lymph nodes 1 | 27
female infertility 1 | 34
hyperactivity 1 | 108
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating glycerol... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 19
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
increased spleen weight 1 | 3
increased startle reflex 1 | 38
increased vertical activity 1 | 18
persistence of hyaloid vascula... 1 | 22
premature death 1 | 5
prolonged RR interval 1 | 2
rib fusion 1 | 2
short tibia 1 | 82
thrombocytopenia 1 | 46
tremors 1 | 34
vertebral fusion 1 | 23

Disease

osteosarcoma 113 | 7,933
ovarian cancer 113 | 8,491
glioblastoma 96 | 5,572
psoriasis 92 | 6,685
medulloblastoma, large-cell 83 | 6,234
Cancer 76 | 2,346
lung cancer 76 | 4,473
lung carcinoma 70 | 2,844
interstitial cystitis 62 | 2,299
atypical teratoid / rhabdoid tumor 57 | 4,369
pilocytic astrocytoma 55 | 3,086
ulcerative colitis 55 | 2,087
invasive ductal carcinoma 53 | 2,950
malignant mesothelioma 53 | 3,163
non-small cell lung cancer 50 | 2,798
Breast cancer 49 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 48 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 47 | 3,289
subependymal giant cell astrocytoma 47 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 43 | 2,956
pancreatic cancer 43 | 2,300
pediatric high grade glioma 43 | 2,712
tuberculosis 42 | 1,563
diabetes mellitus 39 | 1,663
oligodendroglioma 39 | 2,849
lung adenocarcinoma 38 | 2,714
primary Sjogren syndrome 36 | 788
cutaneous lupus erythematosus 35 | 1,056
ependymoma 33 | 2,514
astrocytoma 32 | 1,493
Rheumatoid Arthritis 31 | 1,170
juvenile dermatomyositis 31 | 1,189
Pick disease 30 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,795
pituitary cancer 30 | 1,972
Multiple myeloma 29 | 1,327
adult high grade glioma 29 | 2,148
group 4 medulloblastoma 29 | 1,875
Multiple Sclerosis 28 | 498
primitive neuroectodermal tumor 28 | 3,031
ductal carcinoma in situ 27 | 1,745
breast carcinoma 26 | 1,614
dermatomyositis 26 | 966
cystic fibrosis 25 | 1,670
primary pancreatic ductal adenocarcinoma 25 | 1,271
Carcinoma 24 | 2,147
Down syndrome 24 | 548
Duchenne muscular dystrophy 24 | 602
astrocytic glioma 23 | 2,241
posterior fossa group A ependymoma 23 | 1,511
acute quadriplegic myopathy 22 | 1,157
adrenocortical carcinoma 22 | 1,427
esophageal adenocarcinoma 22 | 737
Hypersensitivity reaction type II disease 21 | 235
group 3 medulloblastoma 21 | 2,254
mucosa-associated lymphoid tissue lymphoma 21 | 480
gastric carcinoma 20 | 832
medulloblastoma 20 | 1,524
Alzheimer's disease 19 | 644
nasopharyngeal carcinoma 19 | 1,056
Asthma 18 | 349
Atopic dermatitis 17 | 944
Waldenstrons macroglobulinemia 17 | 764
active Crohn's disease 16 | 918
colon cancer 15 | 1,475
Atherosclerosis 14 | 275
atypical teratoid/rhabdoid tumor 14 | 1,095
Anemia 13 | 252
IGA Glomerulonephritis 13 | 454
acute myeloid leukemia 13 | 785
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 499
pancreatic carcinoma 13 | 567
sarcoidosis 13 | 368
sonic hedgehog group medulloblastoma 13 | 1,482
Human immunodeficiency virus infectious disease 12 | 129
Kidney disease 12 | 397
Allergic hypersensitivity disease 11 | 123
Hepatitis B 11 | 103
Mammary Neoplasms 11 | 410
periodontitis 11 | 269
posterior fossa group B ependymoma 11 | 1,530
spina bifida 11 | 1,064
Endometriosis 10 | 535
Inflammatory bowel disease 10 | 142
Obesity 10 | 616
head and neck cancer and chronic obstructive pulmonary disease 10 | 237
Dermatitis 9 | 141
Hypertension 9 | 293
Influenza 9 | 142
Peripheral Neuropathy 9 | 303
active ulcerative colitis 9 | 477
chronic lymphocytic leukemia 9 | 244
hepatocellular carcinoma 9 | 550
nephrosclerosis 9 | 329
progressive supranuclear palsy 9 | 674
systemic lupus erythematosus 9 | 172
Becker muscular dystrophy 8 | 187
Myocardial Ischemia 8 | 169
Prostatic Neoplasms 8 | 471
chronic lymphosyte leukemia 8 | 232

Tissue

Blood and immune system 186 | 17,994
Digestive Tract 186 | 18,472
Female tissues 186 | 18,646
Liver and Pancreas 186 | 18,135
Male tissues 186 | 17,968
Respiratory system 186 | 17,483
Urinary Tract 186 | 18,443
Cardiovascular System 185 | 17,957
Endocrine System 185 | 18,511
Nervous System 185 | 18,560
Skin and soft tissues 183 | 18,114

Target Family

Non-IDG 133 | 11,969
Transporter 17 | 473
Enzyme 16 | 4,146
GPCR 10 | 408
Kinase 8 | 634
Ion Channel 4 | 341
Transcription Factor 1 | 1,400

CSPA Cell Line

MedB1 189 | 189
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interferon gamma receptor 1 IFNGR1 Tchem Non-IDG -2.19638 160.9 450
Sialic acid-binding Ig-like lectin 12 SIGLEC12 Tbio Non-IDG -2.35522 224.6 122
P2Y purinoceptor 8 P2RY8 Tbio GPCR -1.00631 7.92 122
Sodium/potassium-transporting ATPase subunit beta-3 ATP1B3 Tclin Transporter -1.08214 10.9 189
Dipeptidyl peptidase 4 DPP4 Tclin Enzyme -3.60140 4091.0 900
Calreticulin CALR Tbio Non-IDG -3.16449 1423.9 650
Protocadherin gamma-C3 PCDHGC3 Tdark Non-IDG -0.62127 4.40 173
Sodium/potassium-transporting ATPase subunit beta-2 ATP1B2 Tclin Transporter -1.33849 19.3 155
Cell adhesion molecule 1 CADM1 Tbio Non-IDG -2.73938 508.3 380
Ras-related protein Rab-5C RAB5C Tbio Enzyme -1.13690 11.1 135