Development Level

Tbio 115 | 11,445
Tclin 23 | 613
Tchem 21 | 1,598
Tdark 4 | 6,588

Collection

GPCR: IDG Consortium (Targets) 2 | 126
RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal behavior 5 | 298
decreased total body fat amoun... 5 | 207
decreased vertical activity 4 | 208
decreased body length 3 | 101
enlarged spleen 3 | 41
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal seminal vesicle morph... 2 | 114
decreased mean corpuscular hem... 2 | 31
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased spleen weight 2 | 10
preweaning lethality, complete... 2 | 979
small superior vagus ganglion 2 | 74
abnormal anxiety-related respo... 1 | 1
abnormal bone structure 1 | 187
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal placenta size 1 | 20
abnormal response to new envir... 1 | 10
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal social-conspecific in... 1 | 3
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 11
abnormal urination 1 | 1
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cataract 1 | 92
decreased T cell number 1 | 15
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased CD4-positive, alpha ... 1 | 4
increased aggression 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
prolonged ST segment 1 | 36
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 111 | 11,493
osteosarcoma 104 | 7,950
Cancer 85 | 2,499
ovarian cancer 84 | 8,520
psoriasis 79 | 6,694
glioblastoma 77 | 5,792
interstitial cystitis 77 | 2,312
lung carcinoma 76 | 2,843
lung cancer 75 | 4,740
medulloblastoma, large-cell 68 | 6,241
adult high grade glioma 55 | 3,801
atypical teratoid / rhabdoid tumor 55 | 5,112
invasive ductal carcinoma 55 | 2,951
tuberculosis 52 | 2,010
cutaneous lupus erythematosus 51 | 1,057
non-small cell lung cancer 50 | 2,890
Astrocytoma, Pilocytic 49 | 3,081
ulcerative colitis 49 | 1,819
ependymoma 47 | 4,679
malignant mesothelioma 44 | 3,232
lung adenocarcinoma 42 | 2,716
Breast cancer 41 | 3,578
Rheumatoid arthritis 40 | 1,191
diabetes mellitus 39 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 38 | 2,955
primary Sjogren syndrome 38 | 735
Multiple Sclerosis 35 | 540
subependymal giant cell astrocytoma 35 | 2,287
pancreatic cancer 34 | 2,398
Hypersensitivity reaction type II disease 33 | 253
group 3 medulloblastoma 33 | 4,104
Kidney cancer 26 | 2,613
dermatomyositis 25 | 966
ductal carcinoma in situ 25 | 1,745
oligodendroglioma 25 | 2,850
cystic fibrosis 24 | 1,696
primitive neuroectodermal tumor 24 | 3,035
Autosomal recessive predisposition 23 | 1,442
breast carcinoma 23 | 1,638
esophageal adenocarcinoma 23 | 737
pituitary cancer 23 | 1,972
primary pancreatic ductal adenocarcinoma 23 | 1,109
astrocytic glioma 22 | 2,597
juvenile dermatomyositis 22 | 1,187
Anemia 21 | 365
Duchenne muscular dystrophy 21 | 601
Pick disease 21 | 1,894
active Crohn's disease 21 | 922
group 4 medulloblastoma 21 | 1,855
Multiple myeloma 20 | 1,332
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
Kidney disease 19 | 430
Liver Cirrhosis, Experimental 19 | 769
Schizophrenia 19 | 1,160
periodontitis 19 | 293
Vascular disease 18 | 319
Waldenstrons macroglobulinemia 18 | 765
colon cancer 18 | 1,478
mucosa-associated lymphoid tissue lymphoma 18 | 484
sarcoidosis 18 | 370
Down syndrome 17 | 499
Human immunodeficiency virus infectious disease 17 | 138
Lymphoproliferative syndrome 17 | 58
nasopharyngeal carcinoma 17 | 1,058
Arthritis 16 | 290
Asthma 16 | 385
astrocytoma 16 | 1,146
gastric carcinoma 16 | 807
Alzheimer's disease 15 | 658
Atopic dermatitis 15 | 952
Chronic Lymphocytic Leukemia 15 | 262
acute myeloid leukemia 15 | 783
Atherosclerosis 13 | 291
Endometriosis 13 | 540
Hepatomegaly 13 | 285
Thrombocytopenia 13 | 197
active ulcerative colitis 13 | 764
adrenocortical carcinoma 13 | 1,428
pediatric high grade glioma 13 | 1,064
Coronary artery disease 12 | 268
Systemic lupus erythematosus 12 | 194
acute quadriplegic myopathy 12 | 1,158
head and neck cancer and chronic obstructive pulmonary disease 12 | 239
nephrosclerosis 12 | 333
Crohn's disease 11 | 321
Dermatitis 11 | 157
Hepatitis B 11 | 108
Liver disease 11 | 237
Pneumonia 11 | 174
Splenomegaly 11 | 190
non-small cell lung carcinoma 11 | 317
Acquired immunodeficiency syndrome 10 | 197
Diarrhea 10 | 253
Hypertension 10 | 396
Influenza 10 | 142
Severe combined immunodeficiency 10 | 51
Arthritis, Rheumatoid 9 | 174
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510

Tissue

Blood and immune system 152 | 16,909
Digestive Tract 152 | 17,369
Endocrine System 152 | 18,159
Female tissues 152 | 17,400
Liver and Pancreas 152 | 16,750
Male tissues 152 | 17,142
Respiratory system 152 | 16,393
Skin and soft tissues 152 | 17,230
Urinary Tract 152 | 16,678
Nervous System 148 | 16,725
Cardiovascular System 147 | 15,192

Target Family

Non-IDG 131 | 12,091
Enzyme 11 | 4,145
GPCR 8 | 408
Transporter 6 | 473
Ion Channel 5 | 344
Kinase 2 | 634

CSPA Cell Line

Lymphoma 163 | 163
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leukocyte-associated immunoglobulin-like receptor 1 LAIR1 Tbio Non-IDG -1.74760 64.2 487
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
VPS10 domain-containing receptor SorCS1 SORCS1 Tbio Non-IDG -1.36030 24.0 81
Complement receptor type 1 CR1 Tbio Non-IDG -3.36509 2362.6 700
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
T-lymphocyte surface antigen Ly-9 LY9 Tbio Non-IDG -1.58527 43.8 383