Development Level

Tbio 119 | 11,445
Tchem 26 | 1,598
Tclin 25 | 613
Tdark 9 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, incomple... 8 | 499
abnormal behavior 7 | 298
preweaning lethality, complete... 5 | 979
decreased total body fat amoun... 4 | 207
enlarged heart 4 | 210
decreased blood urea nitrogen ... 3 | 51
decreased circulating glucose ... 3 | 126
decreased vertical activity 3 | 208
embryonic lethality prior to t... 3 | 278
improved glucose tolerance 3 | 79
increased mean corpuscular vol... 3 | 92
increased or absent threshold ... 3 | 101
increased total body fat amoun... 3 | 134
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
abnormal vertebrae morphology 2 | 18
cardiovascular system phenotyp... 2 | 36
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased heart weight 2 | 27
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
enlarged lymph nodes 2 | 37
enlarged spleen 2 | 41
hyperactivity 2 | 148
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased circulating choleste... 2 | 66
increased mean corpuscular hem... 2 | 96
abnormal bone mineralization 1 | 38
abnormal brain morphology 1 | 13
abnormal coat appearance 1 | 31
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased eosinophil cell numb... 1 | 24
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
enlarged epididymis 1 | 31
female infertility 1 | 60
increased B cell number 1 | 9
increased aggression 1 | 4
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased circulating thyroxin... 1 | 7
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart rate 1 | 23
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
tremors 1 | 39

Disease

Carcinoma 131 | 11,493
ovarian cancer 103 | 8,520
osteosarcoma 96 | 7,950
glioblastoma 88 | 5,792
Cancer 87 | 2,499
lung carcinoma 85 | 2,843
lung cancer 83 | 4,740
psoriasis 82 | 6,694
medulloblastoma, large-cell 69 | 6,241
malignant mesothelioma 64 | 3,232
Astrocytoma, Pilocytic 57 | 3,081
ependymoma 55 | 4,679
non-small cell lung cancer 54 | 2,890
interstitial cystitis 52 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 51 | 3,291
invasive ductal carcinoma 49 | 2,951
atypical teratoid / rhabdoid tumor 47 | 5,112
adult high grade glioma 46 | 3,801
pancreatic cancer 46 | 2,398
Breast cancer 44 | 3,578
subependymal giant cell astrocytoma 44 | 2,287
lung adenocarcinoma 43 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 41 | 2,989
Rheumatoid arthritis 39 | 1,191
group 3 medulloblastoma 39 | 4,104
oligodendroglioma 39 | 2,850
tuberculosis 39 | 2,010
ulcerative colitis 39 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 38 | 2,955
diabetes mellitus 36 | 1,728
cutaneous lupus erythematosus 35 | 1,057
Kidney cancer 33 | 2,613
Multiple Sclerosis 30 | 540
astrocytic glioma 30 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,962
juvenile dermatomyositis 28 | 1,187
Multiple myeloma 27 | 1,332
cystic fibrosis 27 | 1,696
primary Sjogren syndrome 27 | 735
Hypersensitivity reaction type II disease 26 | 253
Schizophrenia 26 | 1,160
Autosomal recessive predisposition 25 | 1,442
ductal carcinoma in situ 25 | 1,745
group 4 medulloblastoma 25 | 1,855
primary pancreatic ductal adenocarcinoma 25 | 1,109
Pick disease 24 | 1,894
breast carcinoma 24 | 1,638
dermatomyositis 24 | 966
pituitary cancer 24 | 1,972
astrocytoma 23 | 1,146
esophageal adenocarcinoma 23 | 737
primitive neuroectodermal tumor 23 | 3,035
Liver Cirrhosis, Experimental 22 | 769
colon cancer 22 | 1,478
Alzheimer's disease 20 | 658
acute quadriplegic myopathy 20 | 1,158
pediatric high grade glioma 20 | 1,064
Waldenstrons macroglobulinemia 19 | 765
active Crohn's disease 19 | 922
gastric carcinoma 19 | 807
Arthritis 18 | 290
Down syndrome 18 | 499
Duchenne muscular dystrophy 18 | 601
Asthma 17 | 385
Atopic dermatitis 17 | 952
active ulcerative colitis 17 | 764
adrenocortical carcinoma 17 | 1,428
Human immunodeficiency virus infectious disease 16 | 138
acute myeloid leukemia 16 | 783
mucosa-associated lymphoid tissue lymphoma 16 | 484
Anemia 14 | 365
Juvenile rheumatoid arthritis 14 | 111
nasopharyngeal carcinoma 14 | 1,058
Breast Neoplasms 12 | 445
Mammary Neoplasms 12 | 425
sarcoidosis 12 | 370
Ankylosing spondylitis 11 | 140
Atherosclerosis 11 | 291
Endometriosis 11 | 540
Vascular disease 11 | 319
posterior fossa group A ependymoma 11 | 468
Acquired immunodeficiency syndrome 10 | 197
Barrett's esophagus 10 | 182
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Hypertension 10 | 396
Intellectual disability 10 | 1,016
Kidney disease 10 | 430
Liver disease 10 | 237
Mental and motor retardation 10 | 608
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
hepatocellular carcinoma 10 | 547
nephrosclerosis 10 | 333
non-small cell lung carcinoma 10 | 317
sonic hedgehog group medulloblastoma 10 | 467
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Splenomegaly 9 | 190

Tissue

Blood and immune system 166 | 16,909
Digestive Tract 166 | 17,369
Endocrine System 166 | 18,159
Female tissues 166 | 17,400
Liver and Pancreas 166 | 16,750
Male tissues 166 | 17,142
Respiratory system 166 | 16,393
Skin and soft tissues 166 | 17,230
Urinary Tract 166 | 16,678
Cardiovascular System 163 | 15,192
Nervous System 163 | 16,725

Target Family

Non-IDG 132 | 12,091
Enzyme 16 | 4,145
Transporter 15 | 473
Kinase 7 | 634
GPCR 5 | 408
Ion Channel 3 | 344
Transcription Factor 1 | 1,400

CSPA Cell Line

L540 179 | 179
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Leukocyte-associated immunoglobulin-like receptor 1 LAIR1 Tbio Non-IDG -1.74760 64.2 487
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Zinc transporter ZIP10 SLC39A10 Tbio Transporter -1.20558 16.3 102
CD276 antigen CD276 Tbio Non-IDG -3.03140 785.5 481