Development Level

Tbio 141 | 11,445
Tchem 33 | 1,598
Tclin 29 | 613
Tdark 15 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, incomple... 11 | 499
abnormal behavior 7 | 298
preweaning lethality, complete... 7 | 979
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
enlarged heart 4 | 210
abnormal embryo size 3 | 220
decreased circulating triglyce... 3 | 79
embryonic lethality prior to t... 3 | 278
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
increased mean corpuscular vol... 3 | 92
increased or absent threshold ... 3 | 101
increased total body fat amoun... 3 | 134
tremors 3 | 39
abnormal bone structure 2 | 187
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal limb bud morphology 2 | 17
abnormal seminal vesicle morph... 2 | 114
abnormal vibrissa morphology 2 | 25
cardiovascular system phenotyp... 2 | 36
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased erythrocyte cell num... 2 | 62
embryonic growth retardation 2 | 106
enlarged spleen 2 | 41
hyperactivity 2 | 148
increased bone mineral content 2 | 108
increased circulating choleste... 2 | 66
male infertility 2 | 123
pallor 2 | 34
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal liver morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal spinal cord morpholog... 1 | 9
abnormal tail movements 1 | 12
abnormal urinary bladder morph... 1 | 11
abnormal vertebrae morphology 1 | 18
absent startle reflex 1 | 24
absent vibrissae 1 | 12
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
increased B cell number 1 | 9
increased aggression 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating thyroxin... 1 | 7
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
pale yolk sac 1 | 25
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 166 | 11,493
ovarian cancer 130 | 8,520
osteosarcoma 117 | 7,950
glioblastoma 113 | 5,792
lung cancer 97 | 4,740
Cancer 95 | 2,499
medulloblastoma, large-cell 93 | 6,241
psoriasis 92 | 6,694
lung carcinoma 86 | 2,843
atypical teratoid / rhabdoid tumor 78 | 5,112
ependymoma 77 | 4,679
malignant mesothelioma 71 | 3,232
Astrocytoma, Pilocytic 68 | 3,081
Breast cancer 67 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 66 | 3,291
non-small cell lung cancer 66 | 2,890
invasive ductal carcinoma 65 | 2,951
adult high grade glioma 60 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 59 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 59 | 2,989
interstitial cystitis 58 | 2,312
group 3 medulloblastoma 57 | 4,104
oligodendroglioma 54 | 2,850
pancreatic cancer 53 | 2,398
ulcerative colitis 51 | 1,819
lung adenocarcinoma 50 | 2,716
subependymal giant cell astrocytoma 50 | 2,287
diabetes mellitus 49 | 1,728
tuberculosis 47 | 2,010
Kidney cancer 46 | 2,613
astrocytic glioma 43 | 2,597
Rheumatoid arthritis 37 | 1,191
cystic fibrosis 37 | 1,696
primitive neuroectodermal tumor 37 | 3,035
juvenile dermatomyositis 36 | 1,187
pituitary cancer 36 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
Autosomal recessive predisposition 34 | 1,442
primary pancreatic ductal adenocarcinoma 34 | 1,109
group 4 medulloblastoma 33 | 1,855
Schizophrenia 31 | 1,160
ductal carcinoma in situ 31 | 1,745
Pick disease 30 | 1,894
Duchenne muscular dystrophy 29 | 601
astrocytoma 29 | 1,146
breast carcinoma 29 | 1,638
dermatomyositis 29 | 966
adrenocortical carcinoma 28 | 1,428
cutaneous lupus erythematosus 28 | 1,057
esophageal adenocarcinoma 28 | 737
Multiple Sclerosis 27 | 540
Multiple myeloma 27 | 1,332
acute quadriplegic myopathy 27 | 1,158
colon cancer 27 | 1,478
primary Sjogren syndrome 27 | 735
Alzheimer's disease 24 | 658
Liver Cirrhosis, Experimental 24 | 769
gastric carcinoma 24 | 807
pediatric high grade glioma 24 | 1,064
Hypersensitivity reaction type II disease 23 | 253
active Crohn's disease 23 | 922
Atherosclerosis 21 | 291
Down syndrome 21 | 499
Asthma 20 | 385
Atopic dermatitis 20 | 952
Breast Neoplasms 20 | 445
Kidney disease 20 | 430
Mammary Neoplasms 20 | 425
Waldenstrons macroglobulinemia 20 | 765
nasopharyngeal carcinoma 20 | 1,058
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 510
Anemia 17 | 365
Arthritis 17 | 290
Liver disease 17 | 237
active ulcerative colitis 17 | 764
Obesity 16 | 678
Vascular disease 15 | 319
mucosa-associated lymphoid tissue lymphoma 15 | 484
Melanoma 14 | 711
aldosterone-producing adenoma 14 | 665
progressive supranuclear palsy 14 | 676
Bipolar Disorder 13 | 666
Coronary artery disease 13 | 268
Endometriosis 13 | 540
Hepatitis B 13 | 108
Hypertension 13 | 396
Inflammatory bowel disease 13 | 151
Intellectual disability 13 | 1,016
Liver Cirrhosis 13 | 181
Liver cancer 13 | 604
acute myeloid leukemia 13 | 783
Dull intelligence 12 | 645
Human immunodeficiency virus infectious disease 12 | 138
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Neurodegenerative disease 12 | 414
Poor school performance 12 | 645
fibroadenoma 12 | 559
posterior fossa group A ependymoma 12 | 468

Tissue

Endocrine System 208 | 18,159
Urinary Tract 207 | 16,678
Digestive Tract 206 | 17,369
Female tissues 206 | 17,400
Liver and Pancreas 206 | 16,750
Male tissues 206 | 17,142
Skin and soft tissues 206 | 17,230
Blood and immune system 205 | 16,909
Respiratory system 205 | 16,393
Nervous System 204 | 16,725
Cardiovascular System 199 | 15,192

Target Family

Non-IDG 152 | 12,091
Enzyme 27 | 4,145
Transporter 17 | 473
GPCR 10 | 408
Kinase 9 | 634
Ion Channel 2 | 344
Transcription Factor 1 | 1,400

CSPA Cell Line

L428 218 | 218
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
KMH2 194 | 194
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Zinc transporter ZIP10 SLC39A10 Tbio Transporter -1.20558 16.3 102
UL-16 binding protein 5 RAET1G Tbio Non-IDG -0.77225 5.67 20
Solute carrier organic anion transporter family member 3A1 SLCO3A1 Tbio Transporter -1.39614 24.1 46
Zinc transporter ZIP6 SLC39A6 Tbio Transporter -1.66663 50.0 172