Development Level

Tbio 129 | 11,445
Tchem 32 | 1,598
Tclin 24 | 613
Tdark 9 | 6,588

Collection

GPCR: IDG Consortium (Targets) 2 | 126
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, incomple... 12 | 499
preweaning lethality, complete... 6 | 979
abnormal behavior 4 | 298
abnormal bone structure 4 | 187
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
increased bone mineral content 4 | 108
enlarged heart 3 | 210
hyperactivity 3 | 148
tremors 3 | 39
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
improved glucose tolerance 2 | 79
increased circulating choleste... 2 | 66
increased circulating glycerol... 2 | 9
increased circulating thyroxin... 2 | 7
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal liver morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal urination 1 | 1
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glycerol... 1 | 16
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased threshold for audito... 1 | 26
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
increased B cell number 1 | 9
increased aggression 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
male infertility 1 | 123
premature death 1 | 5
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
vertebral fusion 1 | 23

Disease

Carcinoma 142 | 11,493
ovarian cancer 116 | 8,520
glioblastoma 100 | 5,792
osteosarcoma 100 | 7,950
lung cancer 91 | 4,740
Cancer 89 | 2,499
psoriasis 87 | 6,694
medulloblastoma, large-cell 79 | 6,241
lung carcinoma 77 | 2,843
ependymoma 70 | 4,679
atypical teratoid / rhabdoid tumor 68 | 5,112
malignant mesothelioma 67 | 3,232
Breast cancer 62 | 3,578
invasive ductal carcinoma 61 | 2,951
non-small cell lung cancer 61 | 2,890
Astrocytoma, Pilocytic 58 | 3,081
adult high grade glioma 56 | 3,801
interstitial cystitis 56 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 54 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 53 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 51 | 2,955
pancreatic cancer 51 | 2,398
ulcerative colitis 50 | 1,819
lung adenocarcinoma 47 | 2,716
oligodendroglioma 47 | 2,850
group 3 medulloblastoma 46 | 4,104
subependymal giant cell astrocytoma 46 | 2,287
diabetes mellitus 45 | 1,728
tuberculosis 42 | 2,010
cystic fibrosis 40 | 1,696
astrocytic glioma 37 | 2,597
pituitary cancer 36 | 1,972
Rheumatoid arthritis 34 | 1,191
Kidney cancer 33 | 2,613
primitive neuroectodermal tumor 33 | 3,035
juvenile dermatomyositis 32 | 1,187
breast carcinoma 31 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,962
Multiple Sclerosis 29 | 540
cutaneous lupus erythematosus 29 | 1,057
ductal carcinoma in situ 29 | 1,745
primary pancreatic ductal adenocarcinoma 29 | 1,109
Alzheimer's disease 27 | 658
Duchenne muscular dystrophy 27 | 601
Schizophrenia 27 | 1,160
Multiple myeloma 26 | 1,332
Pick disease 26 | 1,894
dermatomyositis 26 | 966
esophageal adenocarcinoma 26 | 737
group 4 medulloblastoma 26 | 1,855
Hypersensitivity reaction type II disease 25 | 253
astrocytoma 24 | 1,146
active Crohn's disease 23 | 922
acute quadriplegic myopathy 23 | 1,158
colon cancer 23 | 1,478
primary Sjogren syndrome 23 | 735
Autosomal recessive predisposition 22 | 1,442
Liver Cirrhosis, Experimental 22 | 769
adrenocortical carcinoma 22 | 1,428
gastric carcinoma 21 | 807
Waldenstrons macroglobulinemia 20 | 765
nasopharyngeal carcinoma 20 | 1,058
Atopic dermatitis 19 | 952
active ulcerative colitis 18 | 764
pediatric high grade glioma 18 | 1,064
Down syndrome 17 | 499
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 510
Breast Neoplasms 16 | 445
Mammary Neoplasms 16 | 425
Asthma 15 | 385
Endometriosis 15 | 540
Vascular disease 15 | 319
Arthritis 14 | 290
Kidney disease 14 | 430
mucosa-associated lymphoid tissue lymphoma 14 | 484
Atherosclerosis 13 | 291
Hypertension 13 | 396
Human immunodeficiency virus infectious disease 12 | 138
Liver cancer 12 | 604
Obesity 12 | 678
Prostatic Neoplasms 12 | 495
acute myeloid leukemia 12 | 783
sarcoidosis 12 | 370
Anemia 11 | 365
Bipolar Disorder 11 | 666
Neoplasm Invasiveness 11 | 161
Neurodegenerative disease 11 | 414
pancreatic carcinoma 11 | 562
progressive supranuclear palsy 11 | 676
Coronary artery disease 10 | 268
Crohn's disease 10 | 321
Liver Cirrhosis 10 | 181
Melanoma 10 | 711
Myocardial Infarction 10 | 151
aldosterone-producing adenoma 10 | 665
fibroadenoma 10 | 559
nephrosclerosis 10 | 333
non primary Sjogren syndrome sicca 10 | 891
hepatocellular carcinoma 9 | 547
sonic hedgehog group medulloblastoma 9 | 467

Tissue

Endocrine System 185 | 18,159
Urinary Tract 185 | 16,678
Digestive Tract 184 | 17,369
Female tissues 184 | 17,400
Liver and Pancreas 184 | 16,750
Male tissues 184 | 17,142
Respiratory system 184 | 16,393
Skin and soft tissues 184 | 17,230
Blood and immune system 183 | 16,909
Nervous System 180 | 16,725
Cardiovascular System 178 | 15,192

Target Family

Non-IDG 126 | 12,091
Enzyme 27 | 4,145
Transporter 19 | 473
GPCR 9 | 408
Kinase 9 | 634
Ion Channel 2 | 344
Transcription Factor 2 | 1,400

CSPA Cell Line

KMH2 194 | 194
U-251 MG 405 | 405
Glioblastoma 376 | 376
LN18 359 | 359
HEK 329 | 329
Melanoma NSph 305 | 305
U-2 OS 286 | 286
LN229 283 | 283
RD 277 | 277
T98G 276 | 276
Rh28 265 | 265
ZL55 MPM 262 | 262
HeLa 260 | 260
Adipocytes 259 | 259
B-ALL 255 | 255
MelanomaAdh 243 | 243
A431 242 | 242
U-87 MG 242 | 242
Ruch-2 240 | 240
IMR-32 231 | 231
SDM104 228 | 228
P493-6 227 | 227
SDM5 221 | 221
L428 218 | 218
PASMC 217 | 217
CD4+CD25-Tcells 213 | 213
SDM4 211 | 211
HDLM-2 193 | 193
HCC4012 192 | 192
MedB1 189 | 189
Jurkat 188 | 188
NK cells 182 | 182
NB4 181 | 181
L540 179 | 179
HBL-1 171 | 171
U2932 171 | 171
CaLu3 167 | 167
Lymphoma 163 | 163
SU-DHL-6 160 | 160
LNT229 154 | 154
SU4 (SU-DHL-4) 154 | 154
HL-60 146 | 146
786-O 112 | 112
SDM34 86 | 86
RH4 67 | 67
Braintumor 66 | 66
hMSC 59 | 59

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.90516 156.1 254
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
Zinc transporter ZIP10 SLC39A10 Tbio Transporter -1.20558 16.3 102
UL-16 binding protein 5 RAET1G Tbio Non-IDG -0.77225 5.67 20
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0